Report of three cases of cutaneous reactions to granulocyte macrophage-colony-stimulating factor and a review of the literature

1995 ◽  
Vol 33 (2) ◽  
pp. 262
Author(s):  
Clay J Cockerell
Keyword(s):  
Colony Stimulating Factor ◽  
Review Of The Literature ◽  
Cutaneous Reactions ◽  
Macrophage Colony Stimulating Factor ◽  
Macrophage Colony ◽  
Stimulating Factor

scholarly journals Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects.

1991 ◽  
Vol 173 (3) ◽  
pp. 775-778 ◽  
Author(s):  
A B Kay ◽  
S Ying ◽  
V Varney ◽  
M Gaga ◽  
S R Durham ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Messenger Rna ◽  
Late Phase ◽  
Colony Stimulating Factor ◽  
Interleukin 3 ◽  
Gm Csf ◽  
Cutaneous Reactions ◽  
Macrophage Colony Stimulating Factor ◽  
Macrophage Colony ◽  
Stimulating Factor

Cryostat sections from skin biopsies from 24-h allergen-induced late-phase cutaneous reactions (LPR) in 14 human atopic subjects were hybridized with 35S-labeled RNA probes for a number of cytokines. mRNA was detected for interleukin 3 (IL-3) (8/14), IL-4 (10/14), IL-5 (11/14), and granulocyte/macrophage colony-stimulating factor (GM-CSF) (13/14). Only 5 of 14 gave hybridization signals for IL-2, and 0 of 14 for interferon gamma. Biopsies from diluent controls gave only occasional weak signals. These results suggest that cells infiltrating the site of the 24-h LPR transcribe mRNA for the IL-3, IL-4, IL-5, and GM-CSF gene cluster and support the hypothesis that atopy is associated with preferential activation of cells having a similar cytokine profile to the murine T helper type 2 subset.

Interleukin-34 and macrophage-colony stimulating factor interact to form a heteromeric and functional cytokine

2014 ◽  
Author(s):  
Aude Segaliny ◽  
Regis Brion ◽  
Benedicte Brulin ◽  
Stephane Teletchea ◽  
Julien Jardin ◽  
...  
Keyword(s):  
Colony Stimulating Factor ◽  
Macrophage Colony Stimulating Factor ◽  
Macrophage Colony ◽  
Stimulating Factor
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