Lack of effects of 1,25- and 24,25-dihydroxyvitamin D on parathyroid hormone response to hypocalcemia in cattle

1984 ◽  
Vol 5 (4) ◽  
pp. 171-175 ◽  
Author(s):  
B. Voumard ◽  
U. Trechsel ◽  
J.A. Fischer ◽  
J.W. Blum
2010 ◽  
Vol 226 (1) ◽  
pp. 46-57 ◽  
Author(s):  
Rajiv P. Shrestha ◽  
Christopher V. Hollot ◽  
Stuart R. Chipkin ◽  
Claus P. Schmitt ◽  
Yossi Chait

1979 ◽  
Vol 49 (4) ◽  
pp. 628-630 ◽  
Author(s):  
NANCY D. ADAMS ◽  
THOMAS L. GARTHWAITE ◽  
RICHARD W. GRAY ◽  
THAD C. HAGEN ◽  
JACOB LEMANN

2015 ◽  
Vol 27 (3) ◽  
pp. 1245-1249 ◽  
Author(s):  
B. Falk ◽  
F. Haddad ◽  
P. Klentrou ◽  
W. Ward ◽  
K. Kish ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e104825 ◽  
Author(s):  
Lisa A. Houghton ◽  
Andrew R. Gray ◽  
Michelle J. Harper ◽  
Pattanee Winichagoon ◽  
Tippawan Pongcharoen ◽  
...  

Endocrinology ◽  
1984 ◽  
Vol 114 (3) ◽  
pp. 897-903 ◽  
Author(s):  
KNUT HOVE ◽  
RONALD L. HORST ◽  
E. TRAVIS LITTLEDIKE ◽  
DONALD C. BEITZ

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Takunori Ogawa ◽  
Jun Miyata ◽  
Koichi Fukunaga ◽  
Akihiko Kawana ◽  
Takashi Inoue

Hypercalcemia of malignancy frequently manifests as paraneoplastic syndrome in patients with solid tumors. A 71-year-old man was diagnosed with stage IIIB lung squamous cell carcinoma. Laboratory examination revealed high serum calcium concentration with elevated serum parathyroid hormone-related protein (PTHrP) and 1,25-dihydroxyvitamin D3 levels. As the patient did not respond to the initial treatment with calcitonin, extracellular fluid infusion, and chemotherapy, systemic prednisolone was administered additionally. Thus, the levels of serum calcium normalized and PTHrP and 1,25-dihydroxyvitamin D3 decreased simultaneously. To our knowledge, this is the first case report on the successful treatment of hypercalcemia of malignancy caused by PTHrP and 1,25-dihydroxyvitamin D3 cosecretion in a patient with lung cancer.


2020 ◽  
Vol 13 (8) ◽  
pp. e235209
Author(s):  
Filip Ionescu ◽  
Ioana Petrescu ◽  
Maria Marin

Hypercalcaemia in malignancy is most commonly caused by paraneoplastic secretion of parathyroid hormone-related protein or osteolytic metastases. Very rarely (<1% of cases), the mechanism behind increased serum calcium is increased production of calcitriol (1,25-dihydroxyvitamin D) and even rarer is the occurrence of this phenomenon in solid malignancies, with few such instances reported in the literature. We present a case of a neuroendocrine malignancy originating in the oesophagus associated with calcitriol-induced hypercalcaemia, a phenomenon that has not been previously described. We review the pathophysiology of calcitriol-induced hypercalcaemia and previously reported cases of solid tumours with this presentation.


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