Hepatitis E virus surveillance in Irish homosexual, haemodialysis, intravenous drug abusing and hepatitis C patients . National Virus Reference Laboratory, Trinity Court Drug Treatment Centre and Hepatology Unit, Beaumont Hospital, Dublin, Ireland

Hepatology ◽  
1995 ◽  
Vol 22 (4) ◽  
pp. A387
2018 ◽  
Vol 22 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Guilherme Bricks ◽  
Jorge Figueiredo Senise ◽  
Henrique Pott Junior ◽  
Giuliano Grandi ◽  
Amanda Passarini ◽  
...  

2019 ◽  
Vol 23 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Guilherme Bricks ◽  
Jorge Figueiredo Senise ◽  
Henrique Pott-Jr ◽  
Giuliano Grandi ◽  
Dimas Carnaúba-Jr ◽  
...  

2021 ◽  
Author(s):  
Mariana Cavalheiro Magri ◽  
Caroline Manchiero ◽  
Bianca Peixoto Dantas ◽  
Arielle Karen da Silva Nunes ◽  
Gerusa Maria Figueiredo ◽  
...  

Aim: We investigated the prevalence of anti-hepatitis E virus (HEV) antibodies in patients with chronic hepatitis C and the relationship with liver injury stage. Materials & methods: In total, 451 patients were included and the presence of anti-HEV antibodies was evaluated by ELISA. Results: Anti-HEV IgG antibodies were detected in 45 (10.0%) patients and anti-HEV IgM were detected in two IgG-positive patients (4.4%). The distributions of liver fibrosis, steatosis, inflammatory activity, homeostasis model assessment of insulin resistance and liver enzyme levels were similar between HEV-positive and HEV-negative patients. However, HEV-positive patients had a higher mean age (p = 0.030). The seroprevalence by age group increased from 2.2 (18–30 years) to 53.3% (>60 years). HEV infection was not related to advanced fibrosis. Conclusion: This investigation showed that the seroprevalence of HEV among patients with chronic hepatitis C is similar to that of blood donors in the same region.


2015 ◽  
Vol 45 (11) ◽  
pp. 1146-1151 ◽  
Author(s):  
Andreas Kyvernitakis ◽  
Mahnaz Taremi ◽  
Boris Blechacz ◽  
Jessica Hwang ◽  
Ying Jiang ◽  
...  

1970 ◽  
Vol 1 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Hossein Keyvani ◽  
Mahmood Shamsi Shamabadi ◽  
Saeed Najafifard ◽  
Bashir Hajibeigi ◽  
Farahnaz Fallahian ◽  
...  

Aim: To assess seroprevalence of antibodies to hepatitis E virus (HEV) in healthy blood donors and hepatitis B, C patients. Methods: 450 subjects consisted of 200 blood donors in Tehran blood transfusion center, 100 subjects with hepatitis C and 150 subjects with hepatitis B infection enrolled in this study. The A549 cell line was grown in mixed medium. Cells were infected with hepatitis E virus that was purified from stool sample of a patient confirmed for hepatitis E infection by reverse transcription-polymerase chain reaction (RT-PCR) method. Supernatant of infected cells was used as positive control in our RT- PCR assay. Results: In a total of 450 subjects, 33 (7.3%) had positive anti-HEV by enzyme-linked immunosorbent assay (ELISA). Anti-HEV was seen in (9/200) 4.5%, (7/100) 7%, and (17/150) 11.3% of healthy blood donors, hepatitis C, and hepatitis B subjects, respectively. Difference between two groups was statistically significance (P = 0.028). Difference between frequency of anti-HEV in hepatitis B in relation to healthy blood donors was significant (P = 0.014). Conclusions: HEV infection is more common in subjects with hepatitis B. Keywords: Hepatitis E virus, Seroprevalence, Transmission, Iran   doi: 10.3329/blj.v1i1.2623 Bangladesh Liver Journal Vol.1(1) 2009 p.34-37 


2014 ◽  
Vol 63 (7) ◽  
pp. 975-980 ◽  
Author(s):  
Nidhi S. Chandra ◽  
Durbadal Ojha ◽  
Sanjoy Chatterjee ◽  
Debprasad Chattopadhyay

India is an endemic zone for hepatitis E virus (HEV), which is associated with both epidemic and sporadic infections. In West Bengal, only two hepatitis E outbreaks have been studied to date. However, sporadic cases of HEV infection also occur during inter-epidemic periods. The aim of this hospital-based study was to detect the prevalence of HEV infection in patients with acute sporadic hepatitis in West Bengal, India. Blood samples and clinical information were collected from 285 patients of both sexes and different ages with acute viral hepatitis (AVH) at Calcutta Medical College, Kolkata, a tertiary-care centre. Samples were tested for hepatitis B virus (HBV) surface antigen, anti-hepatitis C virus antibodies, anti-hepatitis A virus IgM and anti-HEV antibodies (IgM and IgG) by ELISA. Only those patients with AVH who were in their first week of illness and negative for all hepatotropic viral antibodies were tested for HEV RNA by reverse transcriptase nested PCR. HEV was identified as the most common cause of AVH (41.8 % of patients), followed by HBV (21.4 %), hepatitis A virus (17.2 %) and hepatitis C virus (4.6 %). Co-infections with more than one virus were found in 22 patients, with HBV–HEV the most common co-infection (3.8 %). Only 14.7 % of patients had no viral marker. To the best of our knowledge, this is the first documented epidemiological study of acute sporadic hepatitis with HEV in the state of West Bengal, India, indicating that this state is an endemic zone for HEV infection.


2021 ◽  
Vol 8 (2) ◽  
pp. 1-5
Author(s):  
Bodhrun Naher ◽  

Viral hepatitis is a serious health problem globally and in endemic countries like Bangladesh. Viral hepatitis may present as mono-infection or co-infection caused by Hepatitis A Virus (HAV), hepatitis B virus, hepatitis C virus, hepatitis D virus, and Hepatitis E Virus (HEV)


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