The solubilities of five cyclic dipeptides in water and in aqueous urea at 298.15 K: a quantitative model for the denaturation of proteins in aqueous urea solutions

The extracellular matrix (ECM) plays a critical role in directing cell behaviour and morphogenesis by regulating gene expression and nuclear organization. Using non-malignant (S1) human mammary epithelial cells (HMECs), it was previously shown that ECM-induced morphogenesis is accompanied by the redistribution of nuclear mitotic apparatus (NuMA) protein from a diffuse pattern in proliferating cells, to a multi-focal pattern as HMECs growth arrested and completed morphogenesis . A process taking 10 to 14 days.To further investigate the link between NuMA distribution and the growth stage of HMECs, we have investigated the distribution of NuMA in non-malignant S1 cells and their malignant, T4, counter-part using a novel model-based image analysis technique. This technique, based on a multi-scale Gaussian blur analysis (Figure 1), quantifies the size of punctate features in an image. Cells were cultured in the presence and absence of a reconstituted basement membrane (rBM) and imaged in 3D using confocal microscopy, for fluorescently labeled monoclonal antibodies to NuMA (fαNuMA) and fluorescently labeled total DNA.

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Motor planning for what matters: Pursuing a quantitative model of effort

PsycEXTRA Dataset ◽

10.1037/e520562012-563 ◽

2009 ◽

Author(s):

Chase J. Coelho ◽

David A. Rosenbaum

Keyword(s):

Motor Planning ◽

Quantitative Model ◽

What Matters

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Cooperative selection of action in tapping: A quantitative model

PsycEXTRA Dataset ◽

10.1037/e665402011-574 ◽

1991 ◽

Cited By ~ 1

Author(s):

Jonathan Vaughan ◽

David A. Rosenbaum ◽

Cathleen Moore

Keyword(s):

Quantitative Model ◽

Selection Of

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Acyl-Enzymes as Thrombolytic Agents in Dog Models of Venous Thrombosis and Pulmonary Embolism

Thrombosis and Haemostasis ◽

10.1055/s-0038-1661069 ◽

1984 ◽

Vol 51 (02) ◽

pp. 248-253 ◽

Cited By ~ 22

Author(s):

R J Dupe ◽

P D English ◽

R A G Smith ◽

J Green

Keyword(s):

Pulmonary Embolism ◽

Side Effects ◽

Venous Thrombosis ◽

Active Site ◽

Acute Pulmonary Embolism ◽

Quantitative Model ◽

Beagle Dog ◽

Thrombosis Model ◽

Derivatives Of

SummaryA quantitative model of venous thrombosis in the beagle dog is described. The model was adapted to permit ageing of isolated experimental clots in vivo. A model of acute pulmonary embolism in this species is also described. In the venous thrombosis model, infusion of streptokinase (SK) or SK-activated human plasmin gave significant lysis but bolus doses of SK. plasmin complex were ineffective. Active site anisoylated derivatives of SK. plasminogen complex, SK-activated plasmin and activator-free plasmin were all active when given as bolus doses in both models. At lytic doses, the acyl-enzymes caused fewer side-effects attributable to plasminaemia than the corresponding unmodified enzymes.

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Service Quality Of Industrial Parks In The View Of Foreign Direct Investment Firms

Restaurant Business ◽

10.26643/rb.v118i11.11254 ◽

2019 ◽

Vol 118 (11) ◽

pp. 552-562

Author(s):

Nguyen Thi Ngan ◽

Bui Huy Khoi

Keyword(s):

Foreign Direct Investment ◽

Service Quality ◽

Direct Investment ◽

Reliability And Validity ◽

Quantitative Model ◽

Industrial Park ◽

Industrial Parks ◽

Average Variance ◽

Composite Reliability

This research aims to assess the service quality of industrial parks (IP) in the view of FDI (foreign direct investment) firms in Vietnam. Data was collected from 270 FDI firms in Vietnam - Singapore Industrial Parks (VSIP) in Vietnam. The proposed research model was based on researches on service quality. Cronbach's Alpha Average Variance Extracted (Pvc),rho (ρA), and Composite Reliability (Pc) tested the reliability and validity of the scale. The analysis results showed that four factors were affecting the servicequality of industrial park in Vietnam being tangibleof VSIP, reliability of VSIP, the empathyof FDI investors, and their assurance. The responsivenessof VSIP did not affect the servicequality of the industrial park. Contents of the article focus on two main issues: the analysis framework of the quantitative model and implicating results todevelop the industrial park services. The limitation of the research was only in VSIP in Vietnam.

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