Influence of the method used on the determination of plasma cholinesterase activity in quail

1994 ◽  
Vol 74 ◽  
pp. 81
Author(s):  
F. Soler ◽  
J.R. García ◽  
L. García ◽  
M.R. Míguez
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Plasma Cholinesterase Activity

Two procedures compared for determination of plasma cholinesterase activity.

1978 ◽  
Vol 24 (5) ◽  
pp. 841-842 ◽  
Author(s):  
H R Crookshank
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Plasma Cholinesterase Activity

Two procedures compared for determination of plasma cholinesterase activity.

1978 ◽  
Vol 24 (5) ◽  
pp. 841-842
Author(s):  
H R Crookshank
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Plasma Cholinesterase Activity

Total cholinesterase in plasma: biological variations and reference limits.

1985 ◽  
Vol 31 (4) ◽  
pp. 546-550 ◽  
Author(s):  
L Lepage ◽  
F Schiele ◽  
R Gueguen ◽  
G Siest
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Total Plasma ◽  
Factors Affecting ◽  
Plasma Cholinesterase Activity ◽  
Genetic Status ◽  
Reference Limits ◽  
Main Factors ◽  
Apparently Healthy

Abstract Factors affecting biological variation in total cholinesterase activity in plasma were studied in a population of 3372 apparently healthy subjects at least four years old. Determination of the dibucaine number, after inhibition of the activity by dibucaine, made it possible to specify the contributions of genetic and physiological characteristics to variations in the total activities by using a statistical method of segmentation. The main factors modifying plasma cholinesterase activity in males are genetic status (dibucaine number) and degree of overweight (subscapular skinfold). In females, hormonal status (puberty or menopause), genetic status (dibucaine number), and the use of oral contraceptives are the factors mainly responsible for the variations of plasma cholinesterase activity. These data allow us to propose reference limits for total plasma cholinesterase.

Determination of the 'no effect' level of dietary parathion for the rat based on a short-term study

1978 ◽  
Vol 56 (4) ◽  
pp. 659-664
Author(s):  
Donald B. Davies ◽  
Bruce J. Holub
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Feed Consumption ◽  
Short Term ◽  
Term Study ◽  
Plasma Cholinesterase Activity ◽  
Short Term Study ◽  
Body Weights ◽  
Effect Level

Adult female rats (220–260 g) were fed a semipurified diet to which the pesticide parathion was either added or excluded. Dietary concentrations of parathion studied ranged between 0.5 and 20 ppm. At designated times following the initiation of treatment, control and treated animals were sacrificed for biochemical assessment. Routine investigations encompassed the determination of plasma cholinesterase activity using a highly sensitive radiometric assay. General nutritional evaluations included measurement of body weights and feed consumption during the growing period. In all studies, feeding parathion at the levels used produced no visible toxic manifestations. Final body weights and feed consumption of treated rats were comparable with control values in most cases. Data obtained from feeding trials of 1–25 days in duration indicated that reduction of plasma cholinesterase activity was most pronounced following 9–11 days of dietary parathion treatment (8 ppm). Feeding parathion at levels of 3.0 ppm or less for 11 days was without effect on plasma cholinesterase activity. Accordingly, the 'no effect' level of parathion for the female rat was judged to be 0.21 mg/kg body weight per day based on this short-term study. Using a safety factor of 100, this 'no effect' level translates into an 'acceptable daily intake' for humans of 2.1 μg parathion/kg body weight per day, which greatly exceeds levels reported to be ingested by Canadians.

Determination of plasma cholinesterase activity by means of a test paper and its use in the field

1970 ◽  
Vol 27 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Jean-Louis Oudart ◽  
Bo Holmstedt
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Test Paper ◽  
Plasma Cholinesterase Activity

scholarly journals Inheritance of low plasma cholinesterase activity in two families with a history of suxamethonium sensitivity

Anaesthesia ◽  
1989 ◽  
Vol 44 (6) ◽  
pp. 480-482
Author(s):  
M. WHITTAKER ◽  
M. BERRY ◽  
J. J. BRITTEN
Keyword(s):  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Plasma Cholinesterase Activity ◽  
History Of

Dose-response relationship for mivacurium inpatients with phenotypically abnormal plasma cholinesterase activity

1995 ◽  
Vol 39 (8) ◽  
pp. 1016-1018 ◽  
Author(s):  
D. OSTERGAARD ◽  
F. S. JENSEN ◽  
L. THEIL SKOVGAARD ◽  
J. VIBY-MOGENSEN
Keyword(s):  
Dose Response ◽  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Plasma Cholinesterase Activity

Plasma Cholinesterase Activity in Female Green Turtles Chelonia mydas Nesting in Laguna de Terminos, Mexico Related to Organochlorine Pesticides in Their Eggs

2017 ◽  
Vol 100 (1) ◽  
pp. 101-105
Author(s):  
Gerardo Rivas-Hernández ◽  
Yaneli May-Uc ◽  
Elsa Noreña-Barroso ◽  
Víctor Cobos-Gasca ◽  
Gabriela Rodríguez-Fuentes
Keyword(s):  
Organochlorine Pesticides ◽  
Cholinesterase Activity ◽  
Chelonia Mydas ◽  
Plasma Cholinesterase ◽  
Plasma Cholinesterase Activity ◽  
Green Turtles ◽  
Laguna De Terminos

Potentiation of Mivacurium Blockade by Low Dose of Pancuronium

2003 ◽  
Vol 98 (5) ◽  
pp. 1057-1062 ◽  
Author(s):  
Cyrus Motamed ◽  
Riad Menad ◽  
Robert Farinotti ◽  
Krassen Kirov ◽  
Xavier Combes ◽  
...  
Keyword(s):  
Acetylcholine Receptors ◽  
Low Dose ◽  
Cholinesterase Activity ◽  
Plasma Concentrations ◽  
Orotracheal Intubation ◽  
Plasma Cholinesterase ◽  
Neuromuscular Blocking ◽  
Pharmacokinetic Analysis ◽  
Plasma Cholinesterase Activity ◽  
Before And After

Background Mivacurium is potentiated by pancuronium to a much greater extent than other relaxants. In a previous investigation we suggested that this potentiation could be due to the ability of pancuronium to inhibit plasma cholinesterase activity, but we did not measure plasma concentrations of mivacurium. In the current study we performed a pharmacokinetic analysis by measuring the plasma concentration of mivacurium when preceded by administration of a low dose of pancuronium. Methods After induction of general anesthesia with propofol and fentanyl and orotracheal intubation, 10 patients (pancuronium-mivacurium group) received 15 microg/kg pancuronium followed 3 min later by 0.1 mg/kg mivacurium, whereas 10 other patients (mivacurium group) received saline followed by 0.13 mg/kg mivacurium 3 min later. Plasma cholinesterase activity was measured before and 3 and 30 min after pancuronium dosing in the pancuronium-mivacurium group and was measured before and after administration of saline in the mivacurium group. Arterial plasma concentrations of mivacurium and its metabolites were measured at 0.5, 1, 1.5, 2, 4, 10, 20, and 30 min after injection. Neuromuscular blockade was assessed by mechanomyography. Results Plasma cholinesterase activity decreased by 26% in the pancuronium-mivacurium group 3 min after injection of pancuronium (P < 0.01) and returned to baseline values 30 min later; however, no significant variation was observed in the mivacurium group. The clearances of the two most active isomers (Cis-Trans and Trans-Trans) were lower in the pancuronium-mivacurium group (17.6 +/- 5.1, 14.7 +/- 5.3 ml. min-1. kg-1, respectively) than in the mivacurium group (32.4 +/- 20.2, 24.8 +/- 13.5 ml. min-1. kg-1; P < 0.05). Conclusions A subparalyzing dose of pancuronium decreased plasma cholinesterase activity and the clearance of the two most active isomers of mivacurium. Pancuronium potentiates mivacurium more than other neuromuscular blocking agents because, in addition to its occupancy of postsynaptic acetylcholine receptors, it slows down the hydrolysis of mivacurium.

Acceleration of Plasma Cholinesterase Activity by Quaternary Ammonium Salts

Science ◽  
1958 ◽  
Vol 128 (3315) ◽  
pp. 92-93 ◽  
Author(s):  
E. G. ERDOS ◽  
F. F. FOLDES ◽  
E. K. ZSIGMOND ◽  
N. BAART ◽  
J. A. ZWARTZ
Keyword(s):  
Quaternary Ammonium ◽  
Cholinesterase Activity ◽  
Plasma Cholinesterase ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Plasma Cholinesterase Activity
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