Evaluation of Gen-Probe DNA hybridization systems for the identification of mycobacterium tuberculosis and mycobacterium avium-intracellulare

1987 ◽  
Vol 8 (2) ◽  
pp. 69-77 ◽  
Author(s):  
Raimundo Gonzalez ◽  
Bruce A. Hanna
2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Christine Goepfert ◽  
Nadine Regenscheit ◽  
Vanessa Schumacher ◽  
Simone Roos ◽  
Christophe Rossier ◽  
...  

Mycobacterium aviumsubsp.avium(Maa) is an intracellular pathogen belonging to theMycobacterium avium-intracellularecomplex (MAC). Reservoirs of MAC are the natural environment, wildlife and domestic animals. In adult bovine, MAC infections are typically caused byMycobacterium aviumsubsp.paratuberculosis(Map). Maa infections in bovine are rarely reported but may cause clinical disease and pathological lesions similar to those observed in paratuberculosis or those induced by members of theMycobacterium tuberculosiscomplex (MTBC). Therefore, differentiation of MAC from MTBC infection should be attempted, especially if unusual mycobacterial lesions are encountered. Four veal calves from a fattening farm dying with clinical signs of otitis media, fever, and weight loss were submitted for necropsy. Samples from affected organs were taken for histologic investigation, bacteriologic culture, and bacterial specification using PCR. Macroscopic thickening of the intestinal mucosa was induced by granulomatous enteritis and colitis. Intracytoplasmic acid-fast bacteria were detected by Ziehl-Neelsen stains and PCR revealed positive results forMycobacterium aviumsubsp.avium. Clinical and pathological changes of Maa infection in veal calves had features ofMycobacterium aviumsubsp.paratuberculosisand the MTBC. Therefore,Mycobacterium tuberculosiscomplex infection should be considered in cases of granulomatous enteritis in calves.


1992 ◽  
Vol 166 (3) ◽  
pp. 686-687 ◽  
Author(s):  
K. E. Squires ◽  
S. T. Brown ◽  
D. Armstrong ◽  
W. F. Murphy ◽  
H. W. Murray

Sign in / Sign up

Export Citation Format

Share Document