Antioxidant defense and oxidant production in different strains of mice in relation to their sensitivity to tumor promotion

1993 ◽  
Vol 15 (5) ◽  
pp. 485
Author(s):  
Robert T. Plutnick ◽  
Gisela Witz
2001 ◽  
Vol 26 (S1) ◽  
pp. S4-S12 ◽  
Author(s):  
Chandan K. Sen

Strenuous physical exercise represents a condition that is often associated with increased production of reactive oxygen species in various tissues. One of the most reliable indices of exercise-induced oxidant production is tissue glutathione oxidation. In humans, exerciseinduced blood glutathione oxidation is rapid and subject to control by antioxidant supplementation. The objective of this brief review is to provide an update of our current understanding of cellular thiols and thiol antioxidants. Cellular thiols are critically important in maintaining the cellular antioxidant defense network. In addition, thiols play a key role in regulating redox-sensitive signal transduction process. Lipoic acid is a highly promising thiol antioxidant supplement. Recent studies have clarified that while higher levels of oxidants may indeed inflict oxidative damage, oxidants are not necessarily deleterious. Under certain conditions oxidants may function as cellular messengers that regulate a multitude of signal transduction pathways. In light of this, the significance of oxidants in various aspects of biology needs to be revisited.


Author(s):  
K.W. Lee ◽  
R.H. Meints ◽  
D. Kuczmarski ◽  
J.L. Van Etten

The physiological, biochemical, and ultrastructural aspects of the symbiotic relationship between the Chlorella-like algae and the hydra have been intensively investigated. Reciprocal cross-transfer of the Chlorellalike algae between different strains of green hydra provide a system for the study of cell recognition. However, our attempts to culture the algae free of the host hydra of the Florida strain, Hydra viridis, have been consistently unsuccessful. We were, therefore, prompted to examine the isolated algae at the ultrastructural level on a time course.


2019 ◽  
Vol 21 (7) ◽  
pp. 693-702
Author(s):  
Lívia Martinez Abreu Soares Costa ◽  
Maiara Andrade de Carvalho Sousa ◽  
Thiago Pereira Souza ◽  
Whasley Ferreira Duarte ◽  
Diego Cunha Zied ◽  
...  

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