Green Tea Dietary Supplements

2013 ◽  
pp. 247-256 ◽  
Author(s):  
David J. Weiss ◽  
Sarah A. Gehrke ◽  
Pengxin Liu ◽  
Randy J. Robinson
Keyword(s):  
Dietary Supplements ◽  
Green Tea

scholarly journals A Non-targeted Approach to Chemical Discrimination Between Green Tea Dietary Supplements and Green Tea Leaves by HPLC/MS

2011 ◽  
Vol 94 (2) ◽  
pp. 487-497 ◽  
Author(s):  
Jianghao Sun ◽  
Pei Chen ◽  
Long-Ze Lin ◽  
James M Harnly
Keyword(s):  
Dietary Supplements ◽  
Green Tea ◽  
Similarity Coefficients ◽  
Tea Leaves ◽  
Liquid Form ◽  
Epicatechin Gallate ◽  
Accurate Mass Measurements ◽  
Chemical Discrimination ◽  
Green Tea Leaves ◽  
Solid Form

Abstract Green tea-based dietary supplements (GTDSs) have gained popularity in the U.S. market in recent years. This study evaluated the phytochemical composition difference of GTDS in comparison with green tea leaves using an HPLC/MS fingerprinting technique coupled with chemometric analysis. Five components that are most responsible for class separation among samples were identified as (-) epicatechin gallate, strictinin, trigalloylglucose, quercetin-3-O-glucosylrhamnosylglucoside, and kaempferol-3-O-galactosyl-rhamnosylglucoside, according to the accurate mass measurements and MS/MS data. The similarity coefficients between the GTDSs in solid form with green tea were 0.55 to 0.91, while for the GTDSs in liquid form they were 0.12 to 0.89, which suggested that chemical composition variance across the GTDSs was significant. Flavonol aglycone concentrations were higher in GTDSs than in tea leaves, indicating the degradation of flavonol glycosides or the oxidation of catechin during the manufacturing and storage processes. In some GTDS samples, compounds were identified that were on the label. The results demonstrate the urgency of QC for GTDS products.

scholarly journals Content of Caffeine and Catechins Measured in Multi-ingredient Dietary Supplements Containing Green Tea: Association with Label Claims and Proprietary Blends

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1375-1375
Author(s):  
Karen Andrews ◽  
Pavel Gusev ◽  
Phuong-Tan Tey ◽  
Sushma Savarala ◽  
Laura Oh ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Standard Errors ◽  
Phytochemical Content ◽  
Funding Sources ◽  
Actual Content ◽  
Label Information ◽  
Label Claim ◽  
Leaf Powder

Abstract Objectives Multi-ingredient dietary supplements (DSs) containing green tea (GT) were analyzed for their phytochemical content (seven catechins and caffeine) as part of a Dietary Supplement Ingredient Database project. The label information required by FDA is the weight of the GT extract or leaf powder, unless it is part of a proprietary blend (only the blend weight needed). Any information about the concentration of GT phytochemicals is voluntary. We assessed the accuracy of the mandatory and voluntary portions of labels and the effect of proprietary blends on the phytochemical content. Methods Two lots of 37 GT DSs, estimated to contain ≥40 mg/serving of GT, were purchased in a variety of market channels. Samples were sent for analysis to two experienced laboratories. Means and standard errors for the analytically measured content of epigallocatechin gallate (EGCG; the most prevalent catechin), the summed content of the catechins (total catechins, TC), and caffeine were derived for each DS and compared to label information. Results The measured content of EGCG, TC, and caffeine showed wide ranges (0 (not detected) - 442, 0–711, and 0–982 mg/day, respectively). DSs with concentration claims for EGCG and caffeine (32% and 43%, respectively) had higher content per serving compared to DSs without such information (P < 0.05). Most DSs with voluntary claims for EGCG, TC or caffeine content (74%) had actual content within ± 20% of the labels. The catechin content was not significantly different in DSs with GT amounts listed on the label (n = 20) compared with DSs listing GT as part of a proprietary blend (n = 17). However, DSs with GT in a blend had significantly more caffeine than those with a label claim for GT amount (means (SE) per day 197 (63) vs. 49 (18), respectively; P = 0.037). Conclusions The actual content of GT constituents such as EGCG, TC and caffeine in multi-ingredient GT DSs varied depending on the labeling formats. DSs with a voluntary label claim for EGCG had significantly higher EGCG content than those with only the required claims. DSs with GT listed as a part of a blend had significantly higher levels of caffeine than products with labeled GT amounts. More complete label information would be beneficial both for consumers and for researchers who track phytochemical intakes and their associations with health outcomes. Funding Sources NIH/ODS and USDA/ARS.

Catechin and Caffeine Content of Green Tea Dietary Supplements and Correlation with Antioxidant Capacity

2006 ◽  
Vol 54 (5) ◽  
pp. 1599-1603 ◽  
Author(s):  
Navindra P. Seeram ◽  
Susanne M. Henning ◽  
Yantao Niu ◽  
Rupo Lee ◽  
H. Samuel Scheuller ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Dietary Supplements ◽  
Green Tea ◽  
Caffeine Content

Disintegration and Dissolution Testing of Green Tea Dietary Supplements: Application and Evaluation of United States Pharmacopeial Standards

2020 ◽  
Vol 109 (6) ◽  
pp. 1933-1942
Author(s):  
Pavel A. Gusev ◽  
Karen W. Andrews ◽  
Sushma Savarala ◽  
Phuong-Tan Tey ◽  
Fei Han ◽  
...  
Keyword(s):  
United States ◽  
Dietary Supplements ◽  
Green Tea ◽  
Dissolution Testing

scholarly journals Acute Liver Failure Caused by ‘Fat Burners’ and Dietary Supplements: A Case Report and Literature Review

2011 ◽  
Vol 25 (3) ◽  
pp. 157-160 ◽  
Author(s):  
Y Radha Krishna ◽  
V Mittal ◽  
P Grewal ◽  
MI Fiel ◽  
T Schiano
Keyword(s):  
Adverse Effects ◽  
Dietary Supplements ◽  
Green Tea ◽  
Histopathological Examination ◽  
Present Report ◽  
Healthy Woman ◽  
Usnic Acid ◽  
Herbal Remedies ◽  
Herbal Extracts ◽  
Herbal Products

Globally, people are struggling with obesity. Many effective, non-conventional methods of weight reduction, such as herbal and natural dietary supplements, are increasingly being sought. Fat burners are believed to raise metabolism, burn more calories and hasten fat loss. Despite patient perceptions that herbal remedies are free of adverse effects, some supplements are associated with severe hepatotoxicity. The present report describes a young healthy woman who presented with fulminant hepatic failure requiring emergent liver transplantation caused by a dietary supplement and fat burner containing usnic acid, green tea and guggul tree extracts. Thorough investigation, including histopathological examination, revealed no other cause of hepatotoxicity. The present case adds to the increasing number of reports of hepatotoxicity associated with dietary supplements containing usnic acid, and highlights that herbal extracts from green tea or guggul tree may not be free of adverse effects. Until these products are more closely regulated and their advertising better scrutinized, physicians and patients should become more familiar with herbal products that are commonly used as weight loss supplements and recognize those that are potentially harmful.

Evaluation of cost versus antioxidant determinants in green tea dietary supplements

2015 ◽  
Vol 55 (4) ◽  
pp. 381-389 ◽  
Author(s):  
Cindy Leslie A. Roberson ◽  
Ehab A. Abourashed ◽  
Nancy Elsharkawy
Keyword(s):  
Dietary Supplements ◽  
Green Tea

Variability in the Antioxidant Activity of Dietary Supplements from Pomegranate, Milk Thistle, Green Tea, Grape Seed, Goji, and Acai: Effects of in Vitro Digestion

2014 ◽  
Vol 62 (19) ◽  
pp. 4313-4321 ◽  
Author(s):  
Susanne M. Henning ◽  
Yanjun Zhang ◽  
Victoria G. Rontoyanni ◽  
Jianjun Huang ◽  
Ru-Po Lee ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Dietary Supplements ◽  
Green Tea ◽  
In Vitro Digestion ◽  
Grape Seed ◽  
Milk Thistle

An LC-ESI/MS method for determining theanine in green tea dietary supplements

2010 ◽  
Vol 397 (5) ◽  
pp. 1773-1777 ◽  
Author(s):  
Mary Bedner ◽  
Lane C. Sander ◽  
Katherine E. Sharpless
Keyword(s):  
Dietary Supplements ◽  
Green Tea ◽  
Esi Ms

scholarly journals Current View on Green Tea Catechins Formulations, Their Interactions with Selected Drugs, and Prospective Applications for Various Health Conditions

2021 ◽  
Vol 11 (11) ◽  
pp. 4905
Author(s):  
Magdalena Cerbin-Koczorowska ◽  
Magdalena Waszyk-Nowaczyk ◽  
Paweł Bakun ◽  
Tomasz Goslinski ◽  
Tomasz Koczorowski
Keyword(s):  
Dietary Supplements ◽  
Green Tea ◽  
The Elderly ◽  
Human Organism ◽  
Current View ◽  
Limiting Factor ◽  
Published Data ◽  
Channel Blockers ◽  
Tea Extract ◽  
The Impact

Green tea extract (GTE) is one of the most popular beverages globally, traditionally prepared from Camelia sinensis leaves. Therefore, it is beneficial to define the impact of GTE and its ingredients on the human organism. Epigallocatechin-3-O-gallate (EGCG) is the most abundant catechin in green tea leaves, belonging to the group of tannins and flavonoids, demonstrating pharmacological activity, but so far, it has not been applied as a drug. This is because EGCG does not present sufficient stability and quickly decomposes through epimerization or autooxidation mechanisms under the influence of light, temperature, changes in pH, or the presence of oxygen. Another limiting factor is EGCG’s low bioavailability after oral administration. Nevertheless, the growing market of dietary supplements together with increasing growing consumption of green tea extracts should prompt us to pay more attention to the safety of both EGCG itself, as well as its influence on other simultaneously used drugs. Previously published data confirm the relationship between healthcare professionals’ access to professional knowledge and their willingness to engage in patient education. For this reason, in this review article, we report the formulations of EGCG and GTE, discuss the data on the safety of EGCG and its possible interactions with drugs, as well as gather various recommendations from medical specialists. Particular attention should be paid to the consumption of green tea during pregnancy and breastfeeding, as well as in the elderly. Patients taking clozapine, digoxin, and warfarin should avoid consuming GTE extracts and dietary supplements containing EGCG. Professional consultation seems especially important for patients treated with statins, calcium channel blockers, or sildenafil.

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