Establishment of Nasopharyngeal Carcinoma Cell Lines, Patient-Derived Xenografts, and Immortalized Nasopharyngeal Epithelial Cell Lines for Nasopharyngeal Carcinoma and Epstein–Barr Virus Infection Studies

2019 ◽  
pp. 85-107
Author(s):  
Y.L. Yip ◽  
W.T. Lin ◽  
W. Deng ◽  
C.M. Tsang ◽  
S.W. Tsao
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epithelial Cell ◽  
Cell Lines ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Carcinoma Cell Lines ◽  
Epithelial Cell Lines ◽  
Epstein Barr ◽  
Barr Virus Infection ◽  
Nasopharyngeal Epithelial Cell

Infection of Human Epithelial Cell Lines by Epstein-Barr Virus

ORL ◽  
1984 ◽  
Vol 46 (4) ◽  
pp. 195-201 ◽  
Author(s):  
Tom Takimoto ◽  
Kazuo Morishita ◽  
Ryozo Umeda ◽  
Hisashi Ogura ◽  
Motoichi Hatano
Keyword(s):  
Epithelial Cell ◽  
Cell Lines ◽  
Epstein Barr Virus ◽  
Human Epithelial Cell ◽  
Barr Virus ◽  
Epithelial Cell Lines ◽  
Epstein Barr

scholarly journals Tumorigenesis of Epstein–Barr Virus-Positive Epithelial Cell Lines Derived from Gastric Tissues in the SCID Mouse

Virology ◽  
2000 ◽  
Vol 277 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Masanao Murakami ◽  
Yoshiko Hoshikawa ◽  
Yukio Satoh ◽  
Hisao Ito ◽  
Masako Tajima ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Lines ◽  
Scid Mouse ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epithelial Cell Lines ◽  
Epstein Barr

scholarly journals Response of Nasopharyngeal Carcinoma Cells to Epstein-Barr Virus Infection In Vitro

2000 ◽  
Vol 80 (8) ◽  
pp. 1149-1160 ◽  
Author(s):  
Chin-Tarng Lin ◽  
Hsiao-Jung Kao ◽  
Jau-Liang Lin ◽  
Wing-Yee Chan ◽  
Han-Chung Wu ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Virus Infection ◽  
Epstein Barr Virus ◽  
Carcinoma Cells ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Epstein Barr ◽  
Barr Virus Infection

scholarly journals Nasopharyngeal Carcinoma Signaling Pathway: An Update on Molecular Biomarkers

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Warut Tulalamba ◽  
Tavan Janvilisri
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus Infection ◽  
Molecular Signaling ◽  
Holistic View ◽  
Barr Virus ◽  
Diagnosis And Prognosis ◽  
Advanced Stages ◽  
Novel Biomarkers ◽  
Epstein Barr ◽  
Barr Virus Infection

Nasopharyngeal carcinoma (NPC) is an uncommon cancer, which has a distinctive ethnic and geographic distribution. Etiology of NPC is considered to be related with a complex interaction of environmental and genetic factors as well as Epstein-Barr virus infection. Since NPC is located in the silent painless area, the disease is usually therefore diagnosed at the advanced stages; hence early detection of NPC is difficult. Furthermore, understanding in molecular pathogenesis is still lacking, pondering the identification of effective prognostic and diagnostic biomarkers. Dysregulation of signaling molecules in intracellular signal transduction, which regulate cell proliferation, apoptosis, and adhesion, underlines the basis of NPC pathogenesis. In this paper, the molecular signaling pathways in the NPC are discussed for the holistic view of NPC development and progression. The important insights toward NPC pathogenesis may offer strategies for identification of novel biomarkers for diagnosis and prognosis.

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