A vision: in silico clinical trials without patients

2021 ◽  
pp. 39-48
Author(s):  
Lesley A. Ogilvie ◽  
Damian T. Rieke ◽  
Hans Lehrach
Keyword(s):  
Clinical Trials ◽  
In Silico

Exploring the Power and the Promise of In Silico Clinical Trials: Possible Applications in COVID-19 Pandemic

2020 ◽  
Author(s):  
Abdelrahman H. Abdelmoneim ◽  
Safinaz I. Khalil ◽  
Hiba A. Osman ◽  
Ayesan Rewane ◽  
Sahar G. Elbage
Keyword(s):  
Clinical Trials ◽  
In Silico

scholarly journals In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Aldo Badano
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Medical Devices ◽  
In Silico ◽  
Lessons Learned ◽  
Patient Access ◽  
High Quality ◽  
Virtual Imaging ◽  
Regulatory Evaluation

AbstractImaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability. Here, I describe some of the principal advantages of in silico imaging trials and enumerate five lessons learned during the design and execution of the first all-in silico virtual imaging clinical trial for regulatory evaluation (the VICTRE study).

Advanced Monte Carlo application for in-silico clinical trials in x-ray breast imaging

2020 ◽  
Author(s):  
Antonio Sarno ◽  
Giovanni Mettivier ◽  
Francesca di Franco ◽  
Gianfranco Paternò ◽  
Angelo Taibi ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Monte Carlo ◽  
In Silico ◽  
Breast Imaging ◽  
X Ray

scholarly journals In-silico pre-clinical trials are made possible by a new simple and comprehensive lumbar belt mechanical model based on the Law of Laplace including support deformation and adhesion effects

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0212681
Author(s):  
Jérôme Molimard ◽  
Rébecca Bonnaire ◽  
Woo Suck Han ◽  
Reynald Convert ◽  
Paul Calmels
Keyword(s):  
Clinical Trials ◽  
In Silico ◽  
Mechanical Model ◽  
Model Based ◽  
The Law

An in silico approach helped to identify the best experimental design, population, and outcome for future randomized clinical trials

2016 ◽  
Vol 69 ◽  
pp. 125-136 ◽  
Author(s):  
Agathe Bajard ◽  
Sylvie Chabaud ◽  
Catherine Cornu ◽  
Anne-Charlotte Castellan ◽  
Salma Malik ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Experimental Design ◽  
In Silico ◽  
Randomized Clinical Trials

Exploiting grid technologies for the simulation of clinical trials: the paradigm of in silico radiation oncology

SIMULATION ◽  
2010 ◽  
Vol 87 (10) ◽  
pp. 893-910 ◽  
Author(s):  
Theodoros Athanaileas ◽  
Andreas Menychtas ◽  
Dimitra Dionysiou ◽  
Dimosthenis Kyriazis ◽  
Dimitra Kaklamani ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Radiation Oncology ◽  
In Silico

IN SILICO CLINICAL TRIALS: A METHOD COMING OF AGE

Shock ◽  
2004 ◽  
Vol 21 (Supplement) ◽  
pp. 99
Author(s):  
G. Clermont ◽  
R Kumar ◽  
J Bartels ◽  
S Chang ◽  
C Chow ◽  
...  
Keyword(s):  
Clinical Trials ◽  
In Silico ◽  
Coming Of Age
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