Sleep in Animals

2017 ◽  
pp. 103-114.e4 ◽  
Author(s):  
Jerome M. Siegel
Keyword(s):  
Sleep In Animals

scholarly journals Sleep disorders in pregnancy

2004 ◽  
Vol 62 (2a) ◽  
pp. 217-221 ◽  
Author(s):  
Eliane Aversa Lopes ◽  
Luciane Bizari Coin de Carvalho ◽  
Priscila Bernal da Costa Seguro ◽  
Rosiane Mattar ◽  
Ademir Baptista Silva ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Sleep Disorders ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
Clinical Interview ◽  
Human Beings ◽  
Normal Sleep ◽  
Function Of Sleep ◽  
In Pregnancy ◽  
Sleep In Animals

CONTEXT: The precise function of sleep in animals and human beings is still unknown, and any sort of physical, social or psychological variation may change the normal sleep-wake cycle. PURPOSE: This research aims is to determine the sleep disorders (SD) for each of the three trimesters of the pregnancy comparing them to the pre-pregnancy state (PG). METHOD: SD were investigated in three hundred pregnant women 11- to 40-years-old through with a brief clinical interview based on directed questions. One hundred pregnant women were considered for each trimester. RESULTS: The rate of pregnant women with insomnia increased by 23% in the 2nd trimester (p< 0.005); the rate for excessive daytime sleepiness (EDS) by 15% in the 1st trimester (p<0.003), 55% in the 2nd trimester (p<0.001) and by 14% in the 3rd trimester (p<0.002); the rate for mild sleepiness increased by 33% in the 2nd trimester (p<0.002) and by 48% in the 3rd trimester (p<0.001); the rate for specific awakenings increased by 63% in the 1st trimester, by 80% in the 2nd trimester and by 84% in the 3rd trimester (p<0.001). CONCLUSION: SD were more frequent during pregnancy comparatively to PG state, mostly at the expenses of EDS and specific awakenings.

Experimental Studies of Sleep in Animals

1977 ◽  
pp. 189-239 ◽  
Author(s):  
P.J. MORGANE ◽  
W.C. STERN ◽  
J.D. BRONZINO
Keyword(s):  
Experimental Studies ◽  
Sleep In Animals

Bed rest for sick adults

1977 ◽  
Vol 15 (26) ◽  
pp. 101-102
Keyword(s):  
Protein Synthesis ◽  
Subarachnoid Haemorrhage ◽  
Rheumatic Fever ◽  
Controlled Trial ◽  
Bed Rest ◽  
Acute Bronchitis ◽  
Controlled Trials ◽  
Rheumatic Carditis ◽  
Wide Range ◽  
Sleep In Animals

Until recently it was generally accepted that bed rest was a valuable part of treating all ill patients. Textbooks stated dogmatically that bed rest - often for weeks or months - was essential for a wide range of maladies, including hepatitis, acute bronchitis,1 measles, 2 subarachnoid haemorrhage,3 acute cholecystitis4 and fever.5 The evidence to support this view was rarely if ever produced. Protein synthesis is increased during sleep in animals6 but it is not clear how this finding relates to bed rest in man. Even when it had become accepted that controlled trials were needed to evaluate drugs for acute and relapsing conditions, rest remained sacrosanct. Thus, in a multicentre controlled trial in rheumatic fever the value of salicylates and corticosteroids was assessed but bed rest was not. Bed rest was considered an ‘essential part of treatment’ in patients with rheumatic carditis.7

Sleep-promoting effects of growth hormone-releasing hormone in normal men

1993 ◽  
Vol 264 (4) ◽  
pp. E594-E598 ◽  
Author(s):  
M. Kerkhofs ◽  
E. Van Cauter ◽  
A. Van Onderbergen ◽  
A. Caufriez ◽  
M. O. Thorner ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Sleep Deprivation ◽  
Rem Sleep ◽  
Fold Increase ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Gh Secretion ◽  
Normal Men ◽  
Sleep Propensity ◽  
Sleep In Animals

Growth hormone-releasing hormone (GHRH) promotes rapid-eye-movement (REM) and non-REM sleep in animals, but there is little direct evidence for a hypnogenic action of GHRH in humans. In the present study, the possible somnogenic effects of intravenous bolus injections of a dose of GHRH eliciting physiological elevations of GH secretion in healthy young men were investigated. GHRH (0.3 micrograms/kg body wt) was given in early sleep [i.e., 1st slow-wave (SW) period], late sleep (i.e., 3rd REM period), and early sleep after sleep deprivation until 0400 h (i.e., 1st SW period). In the absence of sleep deprivation, injection of GHRH in early sleep did not modify SW sleep but increased REM sleep. GHRH administration in the third REM period was followed by a marked decrease of wake and an almost 10-fold increase in SW sleep. When GHRH was administered during the first SW period after sleep deprivation until 0400 h, the duration of wake decreased. Thus GHRH has sleep-promoting effects in young adults, particularly when given at a time of decreased sleep propensity.

Sign in / Sign up

Export Citation Format

Share Document