PEDIATRIC EPILEPSY | Age-Specific Responses to Antiepileptic Drugs

2009 ◽  
pp. 1025-1033
Author(s):  
A.S. Galanopoulou ◽  
S.L. Moshé
Keyword(s):  
Antiepileptic Drugs ◽  
Pediatric Epilepsy

scholarly journals Seizure relapse based upon withdrawal period of antiepileptic drugs in pediatric epilepsy patients

2014 ◽  
Vol 5 (3) ◽  
pp. 118
Author(s):  
Rajat Rana ◽  
Soumadip Das ◽  
S Ramesh ◽  
S Chidambaramnathan ◽  
Ajit Singh ◽  
...  
Keyword(s):  
Antiepileptic Drugs ◽  
Pediatric Epilepsy ◽  
Withdrawal Period ◽  
Seizure Relapse

Discontinuation of Antiepileptic Drugs after Pediatric Epilepsy Surgery

2007 ◽  
Vol 37 (3) ◽  
pp. 200-202 ◽  
Author(s):  
D. Barry Sinclair ◽  
Laura Jurasek ◽  
Matt Wheatley ◽  
Anita Datta ◽  
Donald Gross ◽  
...  
Keyword(s):  
Antiepileptic Drugs ◽  
Epilepsy Surgery ◽  
Pediatric Epilepsy ◽  
Pediatric Epilepsy Surgery

Antiepileptic Drug Selection in Pediatric Epilepsy

2002 ◽  
Vol 17 (2_suppl) ◽  
pp. 2S2-2S8 ◽  
Author(s):  
Patricia K. Crumrine
Keyword(s):  
Antiepileptic Drug ◽  
Antiepileptic Drugs ◽  
Treatment Options ◽  
Epilepsy Syndrome ◽  
Pediatric Epilepsy ◽  
Drug Selection ◽  
Seizure Recurrence ◽  
Selection For ◽  
Selection Of ◽  
Made In

This review article presents information concerning treatment options for various pediatric epilepsy syndromes. The decisions made in the selection of antiepileptic drugs are determined by a number of variables that include, but are exclusive of, risk of seizure recurrence, patient age, epilepsy syndrome, known drug reactions, and prognosis of the epilepsy syndrome. The review discusses issues pertinent to antiepileptic drug selection including simple pharmacokinetic principles, antiepileptic drug formulations, and information concerning clinical studies using some of the antiepileptic drugs. Information is provided concerning the issues of seizure recurrence. Suggested paradigms for antiepileptic drug selection for partial seizures are provided. A table of antiepileptic drug costs is provided for assistance in prescribing and advising families. Psychosocial issues pertinent to the treatment of children are discussed. (J Child Neurol 2002;17:2S2—2S8).

scholarly journals Quality of Life Assessment in Pediatric Epilepsy

2020 ◽  
Author(s):  
Sujana Shakya ◽  
Rajani Shakya ◽  
Prithuja Poudel ◽  
Ashwinee Kumar Shrestha
Keyword(s):  
Quality Of Life ◽  
Antiepileptic Drugs ◽  
Rural Areas ◽  
Focal Epilepsy ◽  
Tertiary Care ◽  
Life Assessment ◽  
Pediatric Epilepsy ◽  
Cross Sectional ◽  
Management Protocol

AbstractQuality of life (QOL) is an accepted health outcome measure in clinical practice. This study was performed to assess QOL in pediatric epilepsy patients and identify demographic and clinical factors influencing it.A cross-sectional study was conducted in the outpatient pediatric department of Dhulikhel Hospital, a tertiary care teaching hospital of Nepal. Parents or caretakers of children receiving one or more antiepileptic drugs were interviewed using QOL childhood epilepsy questionnaire comprising 91 items with seven domains and 16 subscales.All the individual subscales of the questionnaire were found to be compromised with least score on QOL and general health item. Compromised social, physical, psychological, emotional, cognitive as well as behavioral domains were also identified. QOL was found to be effective more in older children and in those from rural areas. They had significant linguistic impairment and lower level of self-esteem. Overall QOL was found to be compromised more in patients with generalized than with focal epilepsy. Seizure frequency and polytherapy were the factors compromising overall QOL.Despite taking appropriate antiepileptic drugs, epilepsy was found to be detrimental to QOL of patients. Hence, QOL assessment should be an important part of epilepsy management protocol.

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