scholarly journals Molecular detection of Merkel cell polyomavirus in basal cell carcinoma and perilesional tissue: a cross-sectional study

2020 ◽  
Vol 95 (4) ◽  
pp. 527-528
Author(s):  
Marianna Tavares Venceslau Gonçalves ◽  
Rafael Brandão Varella ◽  
Núbia Karla de Oliveira Almeida ◽  
Maria Angelica Arpon Marandino Guimarães ◽  
Flávio Barbosa Luz
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Molecular Detection ◽  
Cross Sectional Study ◽  
Merkel Cell Polyomavirus ◽  
Merkel Cell ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Differences in Rate of Complete Excision of Basal Cell Carcinoma by Dermatologists, Plastic Surgeons and General Practitioners: A Large Cross-Sectional Study

Dermatology ◽  
2018 ◽  
Vol 234 (3-4) ◽  
pp. 86-91 ◽  
Author(s):  
Kirtie Ramdas ◽  
Charlotte van Lee ◽  
Samuel Beck ◽  
Patrick Bindels ◽  
Vincent Noordhoek Hegt ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
General Practitioners ◽  
Basal Cell ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Complete Excision ◽  
Cross Sectional

scholarly journals Clinical and histopathological profile of basal cell carcinoma in a population from Criciúma, Santa Catarina, Brazil

2012 ◽  
Vol 87 (4) ◽  
pp. 657-659
Author(s):  
Letícia Pangendler Peres ◽  
Joana Zulian Fiorentin ◽  
Tamise da Silva Baptista ◽  
Deborah Grisolia Fuzina ◽  
Luiz Felipe de Oliveira Blanco
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Local Data ◽  
Santa Catarina ◽  
Cross Sectional ◽  
The Face ◽  
Over 40 Years

Basal cell carcinoma is a local, invasive epidermal neoplasia, the most common type of which is nodular basal cell carcinoma. The objective of the present study was to evaluate the occurrence of basal cell carcinoma, characterizing its distribution in accordance with patients' age, gender, the site of the lesion and its histopathological characteristics. Anatomopathology reports of cases of basal cell carcinoma diagnosed in Criciúma, Santa Catarina, Brazil between June 2005 and June 2007 were analyzed. A descriptive, observational, cross-sectional study was conducted. The majority of patients were females over 40 years of age. Most of the tumors were of the nodular type and were situated on the face. There was ulceration in 27.5%, infiltration in 24.5% and invasion of the deep dermis in 61.8%. Local data must be evaluated in order to emphasize the importance of early diagnosis.

scholarly journals Immunohistochemical expression of P53 in basal cell carcinoma of skin.

2019 ◽  
Vol 26 (09) ◽  
pp. 1500-1505
Author(s):  
Saira Javeed ◽  
Ashok Kumar ◽  
Iram Asrar ◽  
Rabiya Fawad ◽  
Marrium Waqar ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Immunohistochemical Expression ◽  
Cross Sectional ◽  
P53 Expression ◽  
Embedded Blocks ◽  
P53 Immunoreactivity

Objectives: To evaluate the immunohistochemical expression of p53 in basal cell carcinoma of skin. Study Design: It was cross sectional study. Setting: Pathology department of Pakistan Institute of Medical Sciences Hospital, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan. Period: Six months after approval from the Hospital Ethical Committee. Material and Methods: In a descriptive background, 50 cases were involved in the study. Cases were selected by non-probability consecutive sampling technique. Patients of all age group (Males and Females) that was diagnosed as basal cell carcinoma of skin by Hematoxylin & Eosin were included in study. Other epithelial tumors of skin, appendageal tumors and metastatic tumors were excluded. Cases were evaluated for expression of tumor suppressor protein-p53 by immunohistochemical technique applied on formalin-fixed paraffin-embedded blocks. Results: Out of 50 cases, majority of patients were found to be male. Ratio of male to female was 2.6:1. Age range of patient was found between 21-98 years. Mainstream of the patients were between 41-60 years. Nose was found to be frequently involved site 28 (56%) cases. p53 expression was seen in 42 (84%) cases while in 8 (16%) cases p53 expression was not seen. Conclusion: It was found that p53 expression rate is very high in basal cell carcinoma of skin. This high expression of p53 immunoreactivity was explained in terms of its pathogenetic role and mutation in basal cell carcinoma.

scholarly journals IMMUNOEXPRESSION OF CD-10 IN BASAL CELL CARCINOMA AND SQUAMOUS CELL CARCINOMA OF HEAD AND NECK

2021 ◽  
Vol 71 (6) ◽  
pp. 2175-79
Author(s):  
Maria Ilyas ◽  
Muhammad Yasir Rafiq ◽  
Farha Farhan ◽  
Misbah Ali ◽  
Saeed Afzal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Ethical Review ◽  
P Value ◽  
Cross Sectional

Objective: To compare the expression of CD-10 in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Study Design: Comparative cross-sectional study. Place and Duration of Study: Armed Forces Institute of Pathology, Rawalpindi, from Jun 2016 to Jun 2017. Methodology: After taking ethics approval from the ethical review committee AFIP, previously diagnosed, thirty-eight cases of each basal cell carcinoma and squamous cell carcinoma were taken from the histopathology department of Armed Forces Institute of Pathology, Rawalpindi. CD-10 was applied according to standard protocol. The intensity of the CD-10 expression is assessed and categorized into three groups. CD-10 expression less than 10% in the tumour cell was taken as negative (-), 10 to 50% staining was taken as positive (+) and greater than 50% staining in tumour cells was taken as strong positive (++). Results: Out of the total 76 cases included in the study, 9 (24%) were strongly positive (++) whereas 20 (52.6%) were positive (+) and 9 (23.7%) were negative (-) for CD-10 expression. Out of the total 38 cases of SCC 4 (11%) cases showed positive CD-10 expression and 34 (89%) showed negative (-) results. A significant association (p-value <0.001) was seen when CD-10 expression in BCC was compared with SCC. Conclusion: CD-10 expression was higher in basal cell carcinoma when compared to squamous cell carcinoma in which CD-10 expression was very low/absent, hence CD-10 can serve as a useful adjunct marker in differentiating between basal cell carcinoma and squamous cell carcinoma in problematic cases.

Merkel cell polyomavirus in naevoid basal cell carcinoma syndrome-associated basal cell carcinomas and sporadic trichoblastomas

2010 ◽  
Vol 59 (2) ◽  
pp. 140-142 ◽  
Author(s):  
Ahmad Kassem ◽  
Deepa Pantulu ◽  
Kristin Technau ◽  
Anna Kordelia Kurz ◽  
Carlos Diaz ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Merkel Cell Polyomavirus ◽  
Merkel Cell ◽  
Basal Cell Carcinomas

scholarly journals Dermoscopic features of basal cell carcinoma in skin of color: A retrospective cross-sectional study from Puducherry, South India

2021 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
Biswanath Behera ◽  
Rashmi Kumari ◽  
Devinder Mohan Thappa ◽  
Debasis Gochhait ◽  
Bheemanathi Hanuman Srinivas ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
South India ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Indian Patients ◽  
Retrospective Nature

Background: Dermoscopy is useful in the diagnosis of basal cell carcinoma (BCC). However, most descriptions of the dermoscopic features of BCCs are in Caucasians (skin types I-III) and there is a paucity of data in dark-skinned Indian patients. Aims: The aim of this study was to describe the various dermoscopic features of BCC in dark-skinned patients from South India and correlate these with the histopathologic subtypes. Methods: A retrospective observational study of biopsy-proven cases of BCC was conducted at a tertiary care center in South India using nonpolarized contact dermoscopy. Results: Sixty BCCs in 35 patients predominantly of skin phototypes IV or V were studied. These included 32 nodular, 27 superficial and 1 infiltrative type of BCC. The most common dermoscopic features noted were maple leaf-like areas (61.7%), blue-white veils (53.4%), ulceration (48.4%) and short fine telangiectases (46.7%). Ulceration, blue-white veils and arborizing vessels were significantly associated with nodular BCCs, while maple leaf-like areas, red-white structureless areas, multiple small erosions and spoke wheel areas were noted with superficial BCCs. Limitations: The limitations of this study include its retrospective nature, the use of only nonpolarized light for examination, the lack of other histopathological variants of BCC as well as the lack of a comparison group. Conclusion: We report a dermoscopic study of BCC in dark-skinned patients from Puducherry, South India. The blue-white veil was observed in half of the patients and was significantly associated with nodular BCCs. The addition of the blue-white veil to the diagnostic criteria for pigmented BCC could improve the diagnostic accuracy of dermoscopy in Indian patients.

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