We report a novel electrochemical biosensor for the ultrasensitive Hg2+ detection via a signal amplification strategy. This strategy could be easily modified and extended to detect other hazardous heavy metals and nucleic acid.
A transcription-inspired signal amplification strategy that amplifies proteolysis into nucleic acid outputs is presented for the ultrasensitive sensing of protease biomarkers.
A sensitive and label-free DNA detection method was developed based on cascade amplification combining exonuclease-III recycling with rolling circle amplification.
Target-activated transcription for the amplified sensing of protease biomarkers