Near-infrared light remote-controlled intracellular anti-cancer drug delivery using thermo/pH sensitive nanovehicle

2015 ◽  
Vol 17 ◽  
pp. 201-209 ◽  
Author(s):  
Yanping Qin ◽  
Jun Chen ◽  
Ying Bi ◽  
Xiaohan Xu ◽  
Hui Zhou ◽  
...  
RSC Advances ◽  
2014 ◽  
Vol 4 (92) ◽  
pp. 51055-51061 ◽  
Author(s):  
Weidong Ji ◽  
Najun Li ◽  
Dongyun Chen ◽  
Yang Jiao ◽  
Qingfeng Xu ◽  
...  

A NIR light and pH dual responsive nanocarrier was fabricated for anti-cancer drug delivery as well as MRI and fluorescence cell imaging.


Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1899 ◽  
Author(s):  
Evgeny Apartsin ◽  
Nadezhda Knauer ◽  
Valeria Arkhipova ◽  
Ekaterina Pashkina ◽  
Alina Aktanova ◽  
...  

Supramolecular constructions of amphiphilic dendritic molecules are promising vehicles for anti-cancer drug delivery due to the flexibility of their architecture, high drug loading capacity and avoiding off-target effects of a drug. Herein, we report a new class of amphiphilic dendritic species—triazine-carbosilane dendrons readily self-assembling into pH-sensitive dendrimersomes. The dendrimersomes efficiently encapsulate anticancer drugs doxorubicin and methotrexate. Chemodrug-loaded dendrimersomes have dose-related cytotoxic activity against leukaemia cell lines 1301 and K562. Our findings suggest that triazine-carbosilane dendrimersomes are prospective drug carriers for anti-cancer therapy.


Author(s):  
Sally Sabra ◽  
Mona Abdelmoneem ◽  
Mahmoud Abdelwakil ◽  
Moustafa Taha Mabrouk ◽  
Doaa Anwar ◽  
...  

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