Exposure to aluminium chloride during the peripuberal period induces prostate damage in male rats

2022 ◽  
Vol 124 (1) ◽  
pp. 151843
Author(s):  
Franciely A.V.D. Leal ◽  
Gessica D. Gonçalves ◽  
João Gabriel M. Soncini ◽  
Larissa Staurengo-Ferrari ◽  
Victor Fattori ◽  
...  
Keyword(s):  
2011 ◽  
Vol 47 (2) ◽  
pp. 335-343 ◽  
Author(s):  
WA Moselhy ◽  
NA Helmy ◽  
BR Abdel-Halim ◽  
TM Nabil ◽  
MI Abdel-Hamid

2009 ◽  
Vol 22 (4) ◽  
pp. 27-44 ◽  
Author(s):  
Entissar Abdul-Rasoul ◽  
Nathem Hassan ◽  
Karam Al-Mallah

Author(s):  
Essam Eldin Abdelhady Salama

Human impact on the environment was steadily increasing the amounts of aluminum in the ecosystems. This element accumulated in plants and water. Potentially increased its harmful effect; particularly, it induced free radical-mediated cytotoxicity and reproductive toxicity. Propolis was a resinous material collected by bees from bud and exudates of the plants, mixed with bee enzymes, pollen, and wax. Due to its waxy nature and mechanical properties, bees used propolis in the construction and repair of their hives, and as a protective barrier against external invaders, or weathering threats, Current antimicrobial properties of propolis, was helping for wound healing, treatment of burns, herpes simplex and genital herpes. The present work studied the protective effect of propolis against the reproductive toxicity of aluminum chloride in male rats.


Author(s):  
Aline Byrnes ◽  
Elsa E. Ramos ◽  
Minoru Suzuki ◽  
E.D. Mayfield

Renal hypertrophy was induced in 100 g male rats by the injection of 250 mg folic acid (FA) dissolved in 0.3 M NaHCO3/kg body weight (i.v.). Preliminary studies of the biochemical alterations in ribonucleic acid (RNA) metabolism of the renal tissue have been reported recently (1). They are: RNA content and concentration, orotic acid-c14 incorporation into RNA and acid soluble nucleotide pool, intracellular localization of the newly synthesized RNA, and the specific activity of enzymes of the de novo pyrimidine biosynthesis pathway. The present report describes the light and electron microscopic observations in these animals. For light microscopy, kidney slices were fixed in formalin, embedded, sectioned, and stained with H & E and PAS.


Author(s):  
K. Kovacs ◽  
E. Horvath ◽  
J. M. Bilbao ◽  
F. A. Laszlo ◽  
I. Domokos

Electrolytic lesions of the pituitary stalk in rats interrupt adenohypophysial blood flow and result in massive infarction of the anterior lobe. In order to obtain a deeper insight into the morphogenesis of tissue injury and to reveal the sequence of events, a fine structural investigation was undertaken on adenohypophyses of rats at various intervals following destruction of the pituitary stalk.The pituitary stalk was destroyed electrolytically, with a Horsley-Clarke apparatus on 27 male rats of the R-Amsterdam strain, weighing 180-200 g. Thirty minutes, 1,2,4,6 and 24 hours after surgery the animals were perfused with a glutaraldehyde-formalin solution. The skulls were then opened and the pituitary glands removed. The anterior lobes were fixed in glutaraldehyde-formalin solution, postfixed in osmium tetroxide and embedded in Durcupan. Ultrathin sections were stained with uranyl acetate and lead citrate and investigated with a Philips 300 electron microscope.


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