scholarly journals Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: getting the message across

2021 ◽  
pp. 113900
Author(s):  
An-Katrien Minnaert ◽  
Helena Vanluchene ◽  
Rein Verbeke ◽  
Ine Lentacker ◽  
Stefaan C. De Smedt ◽  
...  
Keyword(s):  
Innate Immune ◽  
Immune Activity ◽  
Mrna Therapeutics

scholarly journals Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

Science ◽  
2014 ◽  
Vol 343 (6175) ◽  
pp. 1246949-1246949 ◽  
Author(s):  
B. P. Fairfax ◽  
P. Humburg ◽  
S. Makino ◽  
V. Naranbhai ◽  
D. Wong ◽  
...  
Keyword(s):  
Gene Expression ◽  
Innate Immune ◽  
Immune Activity ◽  
Regulatory Variants

scholarly journals Synovial fluid biomarkers of innate immune activity are predictive of knee osteoarthritis progression

2012 ◽  
Vol 20 ◽  
pp. S91-S92 ◽  
Author(s):  
P.A. Band ◽  
H.-G. Wisniewski ◽  
V. Liublinska ◽  
C. Pattanayak ◽  
E. Colon ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Innate Immune ◽  
Immune Activity ◽  
Osteoarthritis Progression

Effects of Corn-Derived Arabinoxylan-Containing Polysaccharides on Innate Immune Activity

2020 ◽  
Vol 49 (2) ◽  
pp. 119-126
Author(s):  
Sooyong Shin ◽  
Seo Hyun Kim ◽  
Ho Sung Lee ◽  
Dong Ju Kwon ◽  
Sung Ho Jeon
Keyword(s):  
Innate Immune ◽  
Immune Activity

Strategies for modulating innate immune activation and protein production of in vitro transcribed mRNAs

2016 ◽  
Vol 4 (9) ◽  
pp. 1619-1632 ◽  
Author(s):  
Kristin H. Loomis ◽  
Jonathan L. Kirschman ◽  
Sushma Bhosle ◽  
Ravi V. Bellamkonda ◽  
Philip J. Santangelo
Keyword(s):  
Immune Activation ◽  
Protein Production ◽  
Innate Immune ◽  
Innate Immune Activation ◽  
Mrna Therapeutics

This review discusses the challenges associated with IVT mRNA therapeutics and vaccines as well as the current strategies employed to overcome these challenges.

Comparisons of innate immune activity of all known living crocodylian species

2006 ◽  
Vol 143 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Mark E. Merchant ◽  
Kaili Mills ◽  
Noelle Leger ◽  
Erin Jerkins ◽  
Kent A. Vliet ◽  
...  
Keyword(s):  
Innate Immune ◽  
Immune Activity
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