Long-term outcome of primary angioplasty compared with fibrinolysis across age groups: A Danish Multicenter Randomized Study on Fibrinolytic Therapy Versus Acute Coronary Angioplasty in Acute Myocardial Infarction (DANAMI-2) substudy

2008 ◽  
Vol 156 (2) ◽  
pp. 391-396 ◽  
Author(s):  
Emil Loldrup Fosbøl ◽  
Jens Jakob Thune ◽  
Henning Kelbæk ◽  
Henning Rud Andersen ◽  
Kari Saunamäki ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
S. A. Afanasiev ◽  
A. A. Garganeeva ◽  
E. A. Kuzheleva ◽  
A. V. Andriyanova ◽  
D. S. Kondratieva ◽  
...  

The objective of the study was to assess the impact of DM2 at baseline on long-term mortality after acute myocardial infarction (MI) among different age groups. The data were taken from: “Register of Acute Myocardial Infarction.” A total of 862 patients were followed for five years after acute myocardial infarction. The primary endpoint was death from any cause. The patients were categorized into 2 groups based on their ages: group 1—comprised patients older than working age (n=358) and group 2—comprised employable patients (n=504). A total of 208 patients were diagnosed with both cardiovascular disease and DM2. Elderly patients with DM2 had worse prognosis and increased five-year mortality compared with patients of the same age group without DM2. Statistically significant differences in long-term outcomes were found in adult patients (p=0.004) only in group with longer duration of diabetes, unlike the group with DM2 onset. In conclusion, Type 2 DM increased 5-year mortality rate of elderly patients with myocardial infarction. However, younger patients with both myocardial infarction and DM2 had more complications in the early post-MI period compared with patients of the same age group without DM2 but did not show any statistically significant differences in the long-term outcome.


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