812: Maternal mortality from cardiac disease in pregnancy: outcomes from an obstetrical critical care unit in Panama

2012 ◽  
Vol 206 (1) ◽  
pp. S356-S357
Author(s):  
Carlos Montufar ◽  
Alfredo Gei
Author(s):  
K Werdan ◽  
B Patel ◽  
M Girndt ◽  
H Ebelt ◽  
J Schröder ◽  
...  

The prognosis of critically ill cardiac patients in the critical care unit and intensive cardiac care unit depends not only on the underlying cardiac disease, but also on the development of secondary organ complications and failures. Therefore, close monitoring of vital organs is mandatory in all critically ill cardiac patients to detect the development of non-cardiac organ failure as early as possible.


Author(s):  
Karl Werdan ◽  
Brijesh Patel ◽  
Matthias Girndt ◽  
Henning Ebelt ◽  
Jochen Schröder ◽  
...  

The prognosis of critically ill cardiac patients in the critical care unit and intensive cardiac care unit depends not only on the underlying cardiac disease, but also on the development of secondary organ complications and failures. Therefore, close monitoring of vital organs is mandatory in all critically ill cardiac patients to detect the development of non-cardiac organ failure as early as possible.


2020 ◽  
Vol 63 (4) ◽  
pp. 799-807
Author(s):  
JULIA KNYPINSKI ◽  
DIANA S. WOLFE

Heart ◽  
2021 ◽  
pp. heartjnl-2020-318685
Author(s):  
Oktay Tutarel ◽  
Lucia Baris ◽  
Werner Budts ◽  
Mohamad Gamal Abd-El Aziz ◽  
Csilla Liptai ◽  
...  

ObjectiveCardiac disease is a major cause of maternal mortality. Data regarding pregnancy outcomes in women with a systemic right ventricle (sRV) are scarce. We studied pregnancy outcomes in women with an sRV after the atrial switch procedure for transposition of the great arteries (TGA) or congenitally corrected TGA (CCTGA).MethodsThe ESC EORP Registry of Pregnancy and Cardiac Disease is an international prospective registry of pregnant women with cardiac disease. Pregnancy outcomes (maternal/fetal) in all women with an sRV are described. The primary end point was a major adverse cardiac event (MACE) defined as maternal death, supraventricular or ventricular arrhythmias requiring treatment, heart failure, aortic dissection, endocarditis, ischaemic coronary event and other thromboembolic events.ResultsAltogether, 162 women with an sRV (TGA n=121, CCTGA n=41, mean age 28.8±4.6 years) were included. No maternal mortality occurred. In 26 women, at least one MACE occurred, heart failure in 16 (9.8%), arrhythmias (atrial 5, ventricular 6) in 11 (6.7%) and others in 4 (2.5%). Prepregnancy signs of heart failure as well as an sRV ejection fraction <40% were predictors of MACE. One woman experienced fetal loss, while no neonatal mortality was observed. No significant differences were found between women with CCTGA and TGA. In the subset of women who had an echocardiogram before and after pregnancy, no clear deterioration in sRV was observed.ConclusionThe majority of women with an sRV tolerated pregnancy well with a favourable maternal and fetal outcome. Heart failure and arrhythmias were the most common MACE.


Author(s):  
Archana Kumari ◽  
Jyotsna Suri ◽  
Pratima Mittal

Background: Maternal sepsis is one of the leading causes of maternal mortality around the world. The aim of this study was to study the prevalence, clinical profile and fetomaternal outcome of maternal sepsis at a dedicated Obstetric critical care unit of a tertiary care centre of North India. It was retrospective study conducted in tertiary care centre in North IndiaMethods: Women diagnosed as sepsis or septic shock at any point in pregnancy and up to 6 weeks postpartum (irrespective of the source of infection) were included in the study. Demographic, clinical, microbiological and outcome data were recorded from the case sheets of all patients admitted in obstetrical critical care unit between January to December 2016. Outcome measures: Prevalence, bacterial organism, source of infection, mode of delivery, period of gestation, maternal and fetal outcome.Results: The prevalence of maternal sepsis was 16.5/10,000 live births. The number of maternal deaths attributable to sepsis were 35, making the maternal mortality ratio due to sepsis 128/100,000 live births. 87% of the cases were unbooked. 22% presented antenatally while 58% were postpartum and 20% were postabortal. Genital tract infection was most common source of infection. E. coli was the predominant organism in 28% followed by Methicillin resistant staphylococcus aureus in 12%. The mortality from sepsis was very high (78%). 54% of cases required mechanical ventilation and around 7% had to be shifted to intensive care unit for advanced life support and care. Sepsis was associated with preterm delivery and a high perinatal mortality rate.Conclusions: Early recognition of the severity of infection and prompt management by a multidisciplinary team of intensivists, anesthetists, neonatologists, obstetrician, midwives are the key to success. Vigilant infection control measures must be strictly practiced during all pregnancy events.


2001 ◽  
Vol 10 (1) ◽  
pp. 58-63 ◽  
Author(s):  
M Smith ◽  
G.M Cooper ◽  
T.H Clutton-Brock ◽  
M Lewis ◽  
A.D Wilkey ◽  
...  

Author(s):  
Karl Werdan ◽  
Brijesh Patel ◽  
Matthias Girndt ◽  
Henning Ebelt ◽  
Jochen Schröder ◽  
...  

The prognosis of critically ill cardiac patients in the critical care unit and intensive cardiac care unit depends not only on the underlying cardiac disease, but also on the development of secondary organ complications and failures. Therefore, close monitoring of vital organs is mandatory in all critically ill cardiac patients to detect the development of non-cardiac organ failure as early as possible.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
O Tutarel ◽  
L Baris ◽  
M Johnson ◽  
R Hall ◽  
J.W Roos-Hesselink

Abstract Background Cardiac disease is one of the major causes of maternal mortality. We studied pregnancy outcomes in women with a systemic right ventricle (sRV) after the atrial switch procedure for transposition of the great arteries (TGA) or congenitally corrected TGA (CCTGA). Methods The ESC-EORP Registry of Pregnancy and Cardiac Disease is an international prospective registry of pregnant women with cardiac disease. Pregnancy outcomes (maternal and fetal) in women with a sRV are described. The primary endpoint was a major cardiovascular event (MACE) defined as maternal death, supraventricular or ventricular arrhythmias requiring treatment, heart failure, aortic dissection, endocarditis, ischemic coronary event and other thromboembolic events. Results Altogether, 163 women with a sRV (TGA n=121, CCTGA n=42, mean age 28.8±4.6 years) were included. Maternal mortality did not occur. At least one MACE occurred in 26 women (heart failure in 16 (9.8%), arrhythmias (atrial 5, ventricular 6) in 11 (6.7%), and others in 4 (2.5%)). Predictors of MACE were pre-pregnancy signs of heart failure [Odds ratio (OR) 6.05, 95% CI: 1.41–25.97, p=0.02] as well as a sRV ejection fraction below 40% [OR 2.81, 95% CI: 1.18–6.69, p=0.02]. One woman experienced fetal loss, while no neonatal mortality was observed. No significant differences were found between women with CCTGA and TGA. In the subset of women who had an echocardiogram before and after pregnancy, no clear deterioration in sRV was observed. Conclusion The majority of women with a sRV tolerated pregnancy well with a favorable maternal and fetal outcome. Heart failure and arrhythmias were the most common MACE. Funding Acknowledgement Type of funding source: None


Lung India ◽  
2022 ◽  
Vol 39 (1) ◽  
pp. 44
Author(s):  
Rohit Kumar ◽  
Ayush Gupta ◽  
Tejus Suri ◽  
Jyotsna Suri ◽  
Pratima Mittal ◽  
...  

2021 ◽  
pp. 15-19
Author(s):  
Mounika Edupuganti ◽  
Panthagani Vineela

Cardiac disease in pregnancy is one of the common ,indirect obstetric causes of maternal mortality reported incidence varying between 0.5 and 5.9% worldwide. The rise in maternal mortality has been attributed to increasing numbers of women at advanced maternal age undertaking pregnancy, comorbid pre-existing conditions such as diabetes mellitus and hypertension and the growing number of women with congenital heart disease surviving to childbearing. Valvular heart disease is present in 80% of patients with heart disease during pregnancy in developing countries with rheumatic fever as the most common etiology and the mitral valve being the most commonly affected valve, but is uncommon in developed countries. Heart failure complicating rheumatic heart disease in pregnancy has been described in 22% women presenting to clinics in India and few African countries.


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