scholarly journals Short-Term Alcohol Abstinence Improves Antibacterial Defenses of Chronic Alcohol-Consuming Mice against Gut Bacteria–Associated Sepsis Caused by Enterococcus faecalis Oral Infection

2017 ◽  
Vol 187 (9) ◽  
pp. 1998-2007 ◽  
Author(s):  
Makiko Kobayashi ◽  
Akira Asai ◽  
Ichiaki Ito ◽  
Sumihiro Suzuki ◽  
Kazuhide Higuchi ◽  
...  
Keyword(s):  
Enterococcus Faecalis ◽  
Oral Infection ◽  
Gut Bacteria ◽  
Chronic Alcohol ◽  
Short Term ◽  
Alcohol Abstinence

Virulence of Enterococcus faecalis and Impact of Genome‐wide approaches

2011 ◽  
Vol 1 (1) ◽  
pp. 16-24
Author(s):  
Rakesh Kumar Patidar ◽  
Mithilesh Kumar Gupta ◽  
Vinod Singh
Keyword(s):  
Immune Response ◽  
Enterococcus Faecalis ◽  
Virulence Factors ◽  
Host Immune Response ◽  
Oral Infection ◽  
Bacterial Virulence ◽  
Host Defenses ◽  
Opportunistic Pathogens ◽  
New Therapies

Enterococci are well recognized opportunistic pathogens in human and animal infections. Enterococcus faecalis have attracted much attention in recent times due to their increased recognition as an oral infection. The severity of these infections depends on the host immune response and on the presence of virulence factors. Bacterial virulence factors enable a host to replicate and disseminate within a host in part by subverting or eluding host defenses. Application of genome‐wide approaches has led to the identification of new virulence factors that may serve as targets for new therapies. This review discusses the virulence factors of E. faecalis and impact of genome‐wide approaches.

scholarly journals Role of Polymorphonuclear Neutrophils on Infectious Complications Stemming from Enterococcus faecalis Oral Infection in Thermally Injured Mice

2008 ◽  
Vol 180 (6) ◽  
pp. 4133-4138 ◽  
Author(s):  
Yasuhiro Tsuda ◽  
Kenji Shigematsu ◽  
Makiko Kobayashi ◽  
David N. Herndon ◽  
Fujio Suzuki
Keyword(s):  
Enterococcus Faecalis ◽  
Infectious Complications ◽  
Oral Infection ◽  
Polymorphonuclear Neutrophils

Mo1831 Control of Enterococcus Faecalis Translocation by CCL1 Antisense ODN Gene Therapy in Chronic Alcohol-Consuming Mice

2015 ◽  
Vol 148 (4) ◽  
pp. S-721-S-722
Author(s):  
Akira Asai ◽  
Hideko Ohama ◽  
Keisuke Yokohama ◽  
Ken Nakamura ◽  
Yusuke Tsuchimoto ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Enterococcus Faecalis ◽  
Chronic Alcohol

scholarly journals Trans-cinnamaldehyde potently kills Enterococcus faecalis biofilm cells and prevents biofilm recovery

2020 ◽  
Author(s):  
Islam A. A. Ali ◽  
Becky P. K. Cheung ◽  
Jukka. P. Matinlinna ◽  
Celine M. Lévesque ◽  
Prasanna Neelakantan
Keyword(s):  
Antibacterial Activity ◽  
Enterococcus Faecalis ◽  
Metabolic Activity ◽  
Root Canal ◽  
Viable Cell ◽  
Nosocomial Pathogen ◽  
Short Term ◽  
Cell Counts ◽  
First Time

AbstractEnterococcus faecalis is a biofilm-forming, nosocomial pathogen that is frequently isolated from failed root canal treatments. Contemporary root canal disinfectants are ineffective in eliminating these biofilms and preventing reinfection. As a result, there is a pressing need to identify novel and safe antibiofilm molecules. The effect of short-term (5 and 15 min) and long-term (24 h) treatments of TC on the viability of E. faecalis biofilms was compared with currently used root canal disinfectants. Treatment for 15 min with TC reduced biofilm metabolic activity as effective as 1% sodium hypochlorite and 2% chlorhexidine. Treatment with TC for 24 h was significantly more effective than 2% chlorhexidine in reducing the viable cell counts of biofilms. This serendipitous effect of TC was sustained for 10 days under growth-favoring conditions. For the first time, our study highlights the strong antibacterial activity of TC against E. faecalis biofilms, and notably, its ability to prevent biofilm recovery after treatment.

Antibacterial Resistance Against MRSA Oral Infection on Alcohol Fed Mice Recovered 7 Days after Alcohol Abstinence

2017 ◽  
Vol 152 (5) ◽  
pp. S815
Author(s):  
Akira Asai ◽  
Hideko Ohama ◽  
Hidetaka Yasuoka ◽  
Tomohiro Nishikawa ◽  
Ken Nakamura ◽  
...  
Keyword(s):  
Oral Infection ◽  
Antibacterial Resistance ◽  
Alcohol Abstinence
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