A comparison of the central nervous system effects of alcohol at pseudo-steady state in Caucasian and expatriate Japanese healthy male volunteers

Alcohol ◽  
2012 ◽  
Vol 46 (7) ◽  
pp. 657-664 ◽  
Author(s):  
Remco W.M. Zoethout ◽  
Marieke L. de Kam ◽  
Albert Dahan ◽  
Adam F. Cohen ◽  
Joop M.A. van Gerven
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Steady State ◽  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers ◽  
The Central Nervous System

Central nervous system effects of haloperidol on THC in healthy male volunteers

2010 ◽  
Vol 24 (11) ◽  
pp. 1697-1708 ◽  
Author(s):  
M Liem-Moolenaar ◽  
E T te Beek ◽  
M L de Kam ◽  
K L Franson ◽  
R S Kahn ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers

Effects of hypercapnia and hypoxia on inspiratory and expiratory diaphragmatic activity in conscious cats

1994 ◽  
Vol 77 (4) ◽  
pp. 1644-1652 ◽  
Author(s):  
M. Bonora ◽  
M. Boule
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Steady State ◽  
Electromyographic Activity ◽  
Large Reduction ◽  
Before And After ◽  
The Central Nervous System ◽  
State Changes ◽  
Chemical Stimuli ◽  
Adult Cats

The influence of steady-state changes in chemical stimuli on ventilation and electromyographic activity of the diaphragm during both inspiration (total DI) and expiration (total DE) was studied in unanesthetized intact adult cats before and after carotid denervation. In intact animals, during hypercapnia (2 4, and 6% CO2), tidal volume (VT) and total DI increase, whereas total DE did not consistently change. During ambient hypocapnic hypoxia (14, 12, and 10% O2), VT increased only at 10% O2, whereas total DI increased at all levels studied. Total DE increased substantially at 14% O2, persisting up to the end of expiration with 12 and 10% O2. This effect was markedly attenuated during normocapnic hypoxia. During CO hypoxemia (1,700 ppm in air), VT as well as total DI and total DE decreased because of a large reduction in inspiratory and expiratory time elicited by tachypneic breathing. The effects of hypercapnia and hypoxia persisted after carotid denervation. Therefore, 1) in contrast to hypercapnia, hypoxia markedly enhances the expiratory diaphragmatic activity, 1) this expiratory braking mechanism depends on the severity of hypoxia and is partly due to hypocapnia secondary to hypoxia; and 3) because this effect was observed after carotid denervation and during CO hypoxemia, it may arise in the central nervous system, possibly in bulbopontine structures.

Steady-State Pharmacokinetic Properties of Tamsulosin in Healthy Male Volunteers

2013 ◽  
Vol 21 (2) ◽  
pp. 130
Author(s):  
Sook Jin Seong ◽  
Hae Won Lee ◽  
Joomi Lee ◽  
Mi-sun Lim ◽  
Eun Hee Kim ◽  
...  
Keyword(s):  
Steady State ◽  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers ◽  
Pharmacokinetic Properties

scholarly journals Constructive Interference in Steady State Imaging in the Central Nervous System

2011 ◽  
Vol 6 (2) ◽  
pp. 138 ◽  
Author(s):  
Fabrício Guimarães Gonçalves ◽  
Lázaro Luis Faria do Amaral ◽  
◽  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Steady State ◽  
Signal To Noise Ratio ◽  
Cranial Nerves ◽  
High Signal ◽  
Constructive Interference ◽  
Spinal Imaging ◽  
The Central Nervous System ◽  
Noise Ratio

Constructive interference in steady state (CISS) is a fully refocused fast-gradient echo sequence that is mainly used in the assessment of the central nervous system. The most important advantages of steady-state imaging are short acquisition times, high signal-to-noise ratio, and better contrast-to-noise ratio. Owing to its cisternographic effect, CISS is useful in the assessment of the cranial nerves, and can also be used when studying cysts, cystic masses, and neurocysticercosis and in hydrocephalus cases. CISS has been shown to be useful in spinal imaging, epecially in cases of arteriovenous malformation and when it is helpful to better characterise intra- and extramedullary cystic abnormalities.

An Attentional Model for the Conceptual Construction of Units and Number

1981 ◽  
Vol 12 (2) ◽  
pp. 83-94
Author(s):  
Ernst Von Glasersfeld
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Steady State ◽  
Theoretical Model ◽  
Attentional Model ◽  
Reflective Abstraction ◽  
Conceptual Structures ◽  
Novel Approach ◽  
Conceptual Construction ◽  
The Central Nervous System

A theoretical model is proposed that explicates the generation of conceptual structures from unitary sensory objects to abstract constructs that satisfy the criteria generally stipulated for concepts of “number”: independence from sensory properties, unity of composites consisting of units, and potential numerosity. The model is based on the assumption that attention operates not as a steady state but as a pulselike phenomenon that can, but need not, be focused on sensory signals in the central nervous system. Such a view of attention is compatible with recent findings in the neurophysiology of perception and provides, in conjunction with Piaget's postulate of empirical and reflective abstraction, a novel approach to the analysis of concepts that seem indispensable for the development of numerical operations.

Constructive Interference in Steady State Imaging in the Central Nervous System

US Neurology ◽  
2011 ◽  
Vol 07 (01) ◽  
pp. 68
Author(s):  
Fabrício Guimarães Gonçalves ◽  
Lázaro Luis Faria do Amaral ◽  
◽  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Steady State ◽  
Signal To Noise Ratio ◽  
Cranial Nerves ◽  
High Signal ◽  
Constructive Interference ◽  
Spinal Imaging ◽  
The Central Nervous System ◽  
Noise Ratio

Constructive interference in steady state (CISS) is a fully refocused fast-gradient echo sequence that is mainly used in the assessment of the central nervous system. The most important advantages of steady-state imaging are short acquisition times, high signal-to-noise ratio, and better contrast-to-noise ratio. Owing to its cisternographic effect, CISS is useful in the assessment of the cranial nerves, and can also be used when studying cysts, cystic masses, and neurocysticercosis and in hydrocephalus cases. CISS has been shown to be useful in spinal imaging, especially in cases of arteriovenous malformation and when it is helpful to better characterize intra- and extramedullary cystic abnormalities.

scholarly journals Food interaction and steady-state pharmacokinetics of itraconazole capsules in healthy male volunteers.

1993 ◽  
Vol 37 (4) ◽  
pp. 778-784 ◽  
Author(s):  
J A Barone ◽  
J G Koh ◽  
R H Bierman ◽  
J L Colaizzi ◽  
K A Swanson ◽  
...  
Keyword(s):  
Steady State ◽  
Healthy Male ◽  
Food Interaction ◽  
Healthy Male Volunteers ◽  
Male Volunteers

scholarly journals The anatomy and immunology of vasculature in the central nervous system

2019 ◽  
Vol 4 (37) ◽  
pp. eaav0492 ◽  
Author(s):  
Panagiotis Mastorakos ◽  
Dorian McGavern
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Steady State ◽  
Cerebral Ischemia ◽  
Autoimmune Disease ◽  
Immune Responses ◽  
Anatomical Variations ◽  
Structural Variations ◽  
Cerebrovascular Injury ◽  
The Central Nervous System

Barriers between circulation and the central nervous system (CNS) play a key role in the development and modulation of CNS immune responses. Structural variations in the vasculature traversing different anatomical regions within the CNS strongly influence where and how CNS immune responses first develop. Here, we provide an overview of cerebrovascular anatomy, focusing on the blood-CNS interface and how anatomical variations influence steady-state immunology in the compartment. We then discuss how CNS vasculature is affected by and influences the development of different pathophysiological states, such as CNS autoimmune disease, cerebrovascular injury, cerebral ischemia, and infection.

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