Effects of medicinal mushroom (Sparassis crispa) on wound healing in streptozotocin-induced diabetic rats

2009 ◽  
Vol 197 (4) ◽  
pp. 503-509 ◽  
Author(s):  
A.-Hon Kwon ◽  
Zeyu Qiu ◽  
Mamiko Hashimoto ◽  
Kyosuke Yamamoto ◽  
Takashi Kimura
2020 ◽  
Vol 22 (8) ◽  
pp. 731-741
Author(s):  
Muhammad Toseef Zahid ◽  
Muhammad Idrees ◽  
Iram Abdullah ◽  
Wei Ying ◽  
Asmaa Hussein Zaki ◽  
...  

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 643-P ◽  
Author(s):  
YANFEI HAN ◽  
LINDONG LI ◽  
YANJUN LIU ◽  
YOU WANG ◽  
CHUNHUA YAN ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1872
Author(s):  
Hamideh Afzali ◽  
Mohammad Khaksari ◽  
Sajad Jeddi ◽  
Khosrow Kashfi ◽  
Mohammad-Amin Abdollahifar ◽  
...  

Impaired skin nitric oxide production contributes to delayed wound healing in type 2 diabetes (T2D). This study aims to determine improved wound healing mechanisms by acidified nitrite (AN) in rats with T2D. Wistar rats were assigned to four subgroups: Untreated control, AN-treated control, untreated diabetes, and AN-treated diabetes. AN was applied daily from day 3 to day 28 after wounding. On days 3, 7, 14, 21, and 28, the wound levels of vascular endothelial growth factor (VEGF) were measured, and histological and stereological evaluations were performed. AN in diabetic rats increased the numerical density of basal cells (1070 ± 15.2 vs. 936.6 ± 37.5/mm3) and epidermal thickness (58.5 ± 3.5 vs. 44.3 ± 3.4 μm) (all p < 0.05); The dermis total volume and numerical density of fibroblasts at days 14, 21, and 28 were also higher (all p < 0.05). The VEGF levels were increased in the treated diabetic wounds at days 7 and 14, as was the total volume of fibrous tissue and hydroxyproline content at days 14 and 21 (all p < 0.05). AN improved diabetic wound healing by accelerating the dermis reconstruction, neovascularization, and collagen deposition.


2020 ◽  
Vol 187 ◽  
pp. 110647 ◽  
Author(s):  
Peng Zhang ◽  
Libang He ◽  
Jie Zhang ◽  
Xifan Mei ◽  
Yiyao Zhang ◽  
...  
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