Results of a prospective thyroid ultrasound screening program in adenomatous polyposis patients

2014 ◽  
Vol 208 (5) ◽  
pp. 764-769 ◽  
Author(s):  
Emily Steinhagen ◽  
Vanessa W. Hui ◽  
Rachel A. Levy ◽  
Arnold J. Markowitz ◽  
Stephanie Fish ◽  
...  
Keyword(s):  
Screening Program ◽  
Ultrasound Screening ◽  
Thyroid Ultrasound ◽  
Adenomatous Polyposis

scholarly journals Ultrasound Screening for Thyroid Carcinoma in Childhood Cancer Survivors: A Case Series

2008 ◽  
Vol 93 (12) ◽  
pp. 4840-4843 ◽  
Author(s):  
Enrico Brignardello ◽  
Andrea Corrias ◽  
Giuseppe Isolato ◽  
Nicola Palestini ◽  
Luca Cordero di Montezemolo ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Outcome Measure ◽  
Childhood Cancer Survivors ◽  
Ultrasound Screening ◽  
Thyroid Ultrasound ◽  
Main Outcome Measure ◽  
Head Neck

Context: Childhood cancer survivors need regular monitoring into young adulthood and beyond, because they are at risk for developing late-onset complications of cancer therapy, including second malignancies. Objective: This study focuses on the use of thyroid ultrasound to screen for thyroid carcinoma in a population of childhood cancer survivors. Patients: A total of 129 subjects who had received radiotherapy to the head, neck, or upper thorax for a pediatric cancer were studied in the setting of a long-term follow-up unit. Design: Thyroid ultrasound usually began 5 yr after radiotherapy and was repeated every third year, if negative. Median follow-up time since childhood cancer diagnosis was 15.8 yr (range 6.1–34.8 yr). Solid thyroid nodules were found in 35 patients. Fine-needle aspiration was performed in 19 patients, of which 14 had nodules above 1 cm. Main Outcome Measure: The main outcome measure was the finding of not palpable thyroid cancers. Results: Cytological examination of specimens diagnosed papillary carcinoma in five patients who underwent surgery. The cytological diagnosis of papillary thyroid carcinoma was confirmed in all cases by histological examination. Notably, only two of these patients had palpable nodules; the other three were smaller than 1 cm and were detected only by ultrasound. However, histological examination showed nodal metastases in two of these. Conclusions: Although ultrasound screening for thyroid cancer in the general population is not cost effective and could lead to unnecessary surgery, due to false positives, we believe that in childhood cancer survivors who received radiotherapy involving the head, neck, or upper thorax, it would be worthwhile.

scholarly journals Ultrasound screening program for detection of fetal malformations. Past and current status.

1982 ◽  
Vol 10 (s2) ◽  
pp. 79-80
Author(s):  
M. S. Ramzin ◽  
M. J. Hinselmann ◽  
F. Allemann ◽  
S. Näpflin
Keyword(s):  
Screening Program ◽  
Current Status ◽  
Ultrasound Screening ◽  
Fetal Malformations

Screening Program of Abdominal Aortic Aneurysm

Angiology ◽  
2019 ◽  
Vol 70 (5) ◽  
pp. 407-413 ◽  
Author(s):  
Muriel Sprynger ◽  
Michel Willems ◽  
Hendrik Van Damme ◽  
Benny Drieghe ◽  
J. C. Wautrecht ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Screening Program ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Ultrasound Screening ◽  
Care Providers ◽  
Abdominal Ultrasonography ◽  
Screening Programs ◽  
Abdominal Aortic ◽  
Elective Repair

In Europe, the prevalence of abdominal aortic aneurysms (AAAs) in the elderly population (≥65 year old) has declined in the past decades to <4%. Aneurysmal degeneration of the aorta is a serious and potentially life-threatening vascular disease. Abdominal aortic aneurysms typically develop subclinically and often only become symptomatic when complicated by impending rupture. Most AAAs are discovered incidentally while investigating for an unrelated pathology. Ruptured AAA is the tenth leading cause of death in Belgium (0.32% of all deaths in 2014). Health-care providers have emphasized the importance of early detection of AAA and elective repair when the rupture risk outweighs operative risk (usual diameter threshold of 55 mm). Routine AAA screening programs, consisting of a single abdominal ultrasonography at the age of 65 years, aim to reduce the number of AAA-related deaths. Does population-based ultrasound screening for AAA achieve its objective and is it cost-effective? This literature review tries to answer these challenging questions.

Natural History of Thyroid Disease in Children with PTEN Hamartoma Tumor Syndrome

2020 ◽  
Author(s):  
Jessica R Smith ◽  
Enju Liu ◽  
Alanna J Church ◽  
Elizabeth Asch ◽  
Christine E Cherella ◽  
...  
Keyword(s):  
Natural History ◽  
Thyroid Nodule ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Thyroid Nodules ◽  
Ultrasound Screening ◽  
Thyroid Ultrasound ◽  
Autoimmune Thyroid ◽  
Pten Hamartoma Tumor Syndrome ◽  
History Of

Abstract Context Thyroid ultrasound screening is recommended in children with PTEN hamartoma tumor syndrome (PHTS) due to increased risk of thyroid neoplasia, but the natural history of thyroid disease in children with PHTS is unclear. Objective Determine the prevalence and natural history of thyroid disease in children with PHTS. Design Retrospective cohort study (1998-2019). Setting Academic pediatric hospital. Patients Individuals with genetically confirmed PHTS diagnosed before age 19 years. Interventions Description of clinical, thyroid ultrasound, and laboratory characteristics. Main Outcome Measures Prevalence of thyroid nodules ≥10mm diameter, and time course and risk factors for nodule development, assessed by Cox regression analysis. Secondary outcomes included thyroid nodule requiring biopsy, other ultrasound findings, and prevalence of autoimmune thyroid disease. Results Among 64 subjects with PHTS, 50 underwent thyroid ultrasound. A thyroid nodule ≥10mm was diagnosed in 22/50 (44%) subjects at median (range) age 13.3 (7.0-22.9) years. Nodules were diagnosed earlier in females than in males [10.8 (7.0-17.9) vs. 14.2 (9.9-22.9) years, p=0.009]. In multivariate analysis, risk of thyroid nodules was significantly associated with female sex (HR 2.90, 95% CI 1.16-7.27, p=0.02) and inversely associated with the presence of neurological findings of PHTS (HR 0.27, 95% CI 0.10-0.69, p=0.007). Abnormal-appearing lymph nodes with echogenic foci were observed by ultrasound in 20% of subjects, but these were not associated with malignancy. Autoimmune thyroid disease was present in 10/33 (30.3%) of subjects in whom it was assessed. Conclusion Thyroid disease is common in children with PHTS. This study supports current consensus recommendations for ultrasound screening.

scholarly journals Ultrasound screening for cervical, abdominal and scrotal malignant and benign abnormalities in children

2021 ◽  
Author(s):  
Grzegorz Jedrzejewski ◽  
Agnieszka Zaucha-Prazmo ◽  
Albert Matera ◽  
Magdalena Wozniak ◽  
Marcin Inglot ◽  
...  
Keyword(s):  
Developmental Disorders ◽  
Screening Program ◽  
Precancerous Lesions ◽  
Pediatric Population ◽  
Abdominal Ultrasound ◽  
High Tech ◽  
Ultrasound Screening ◽  
Asymptomatic Children ◽  
Scrotal Ultrasound ◽  
Cancer In Children

IntroductionUltrasonography plays an important role in evaluation of many diseases in pediatric population. The noninvasiveness of the method allows to its wide use in children. It is a first-line diagnostic test for detecting lymphadenopathy, benign and malignant abnormalities of the thyroid gland, abdominal structures or testes in boys. The Ultrasound Screening Program “No to Cancer in Children” was introduced to detect neoplastic lesions and possible developmental disorders in children with no symptoms to allow early diagnosis.Material and methodsThe children were scanned in special mobile ambulance - Ronald McDonald Care Mobile, equipped with two high-tech ultrasound devices. Ultrasound scans, including cervical, abdominal, pelvical and scrotal ultrasound were performed in population of asymptomatic children. In the years 2006-2019, 67.594 children, 34.892 boys and 32.702 girls aged from 9 months to 6 years were examined.ResultsTotally, 18.544 various abnormalities were detected. In case of the neck they were found in 7542 children, which represent nearly 11.2% of all patients. Changes in abdominal ultrasound were found in 4.496 cases (6.65%). Abnormalities of the male reproductive system were detected in 6.474 boys (18.5%). Twelve tumors were detected.ConclusionsScreening has proved to be very useful for the early identification cancerous as well as precancerous lesions. It is also worth continuing for a reason of effective detection of other childhood anomalies.

Outcome of thyroid ultrasound screening in FAP patients with a normal baseline exam

2018 ◽  
Vol 18 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Marc Monachese ◽  
Gautam Mankaney ◽  
Rocio Lopez ◽  
Margaret O’Malley ◽  
Lisa Laguardia ◽  
...  
Keyword(s):  
Ultrasound Screening ◽  
Thyroid Ultrasound

Prenatal Diagnosis of Urinary Tract Abnormalities by Ultrasound

PEDIATRICS ◽  
1986 ◽  
Vol 78 (5) ◽  
pp. 879-883
Author(s):  
Ingemar Helin ◽  
Per-Håkan Persson
Keyword(s):  
Prenatal Diagnosis ◽  
Urinary Tract ◽  
Screening Program ◽  
Renal Scarring ◽  
Epidemiologic Study ◽  
Posterior Urethral Valve ◽  
Renal Tissue ◽  
Ultrasound Screening ◽  
Urinary Tract Abnormalities ◽  
Fetal Malformations

The capacity of a general ultrasound screening program to detect fetal malformations affecting the urinary tract was evaluated in an epidemiologic study. A total of 11,986 pregnant women, representing 97% of the pregnant population in Malmö, Sweden, from April 1978 through August 1983 were examined. On routine examinations performed by midwives in the 17th and 33rd gestational weeks, the fetal anatomy was carefully surveyed. The overall frequency of fetal malformations was 0.5%, with urinary tract abnormalities representing approximately 50% of the total number. In 20 of 33 cases, the ultrasound findings were those of hydronephrosis or hydroureter. In ten cases, a cystic renal malformation was found, and the remaining three cases represented double renal pelvis, Potter syndrome, and posterior urethral valve. A total of 28 abnormalities were unilateral and five bilateral. No case of unilateral absence of renal tissue was noted prenatally. Prenatal diagnosis of urinary tract abnormalities known to precipitate neonatal urosepsis and subsequent renal scarring and other complications makes it possible to start an early antibiotic prophylaxis regimen. A complete workup of the infants can be started early and before life-threatening complications occur.

Sign in / Sign up

Export Citation Format

Share Document