The aim of the study. To study the association between lesions in gastroesophageal reflux disease (GERD) and erosive ulcer in schoolchildren of Siberia (Russia). Materials and Methods. We performed the cross-section survey for the schoolchildren aged from 7 to 17 in the cities of Tyva Republic, Evenkia and Buryatia (Russia) using the questionnaires in order to reveal gastric intestinal complaints. We have examined 1535 schoolchildren in Tyva, 1369 in Evenkia and 790 in Buryatia. GERD had been diagnosed when heartburn was marked in accordance with international consensus for pediatric populations. In each region, we performed esophageogastroduodenoscopy in schoolchildren with gastric intestinal complaints picked up by random (283 in Tyva, 205 in Evenkia and 110 in Buryatia). Results. In Siberia schoolchildren GERD prevalence amounted to 6.4%. This index in Tyva Republic was 9.5%, being higher than in Buryatia (4.1%; p=0,0001) and Evenkia (4.2%; p=0,0001). In Tyva Republic, GERD erosive variant was found to show the tendency to increase. The destructive process in stomach mucosa and duodenum in the examined schoolchildren had been diagnosed in 10.7% subjects (in 15.5% schoolchildren of Tyva Republic as compared to 7.3% in children of Buryatia (p=0,0297) and 5.9% in Evenkia (p=0,0009)). In children with erosive ulcer lesions of the gastroduodenal area, the comorbidity of esophageal lesions was revealed more frequently. Conclusion. There is the association between GERD and erosive ulcer lesions in the mucosa of the gastric duodenal area in Siberia schoolchildren. Its severity shows territorial distinctions.
Personal, academic and stress correlates of gastroesophageal reflux disease among college students in southwestern Saudi Arabia: A cross-section study
