scholarly journals Personal and Family Medical History Correlates of Rheumatoid Arthritis

2008 ◽  
Vol 18 (6) ◽  
pp. 433-439 ◽  
Author(s):  
Anneclaire J. de Roos ◽  
Glinda S. Cooper ◽  
Michael C. Alavanja ◽  
Dale P. Sandler
Keyword(s):  
Rheumatoid Arthritis ◽  
Medical History ◽  
Family Medical History

scholarly journals The Latent Tuberculin Test after 1-year Therapy with Anti-TNF in Babylon, Iraq

2018 ◽  
Vol 26 (8) ◽  
pp. 144-150
Author(s):  
Ali Alkazzaz ◽  
Murtadha Najah Jawad ◽  
Zeyad Tareq Kareem
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Medical History ◽  
Demographic Data ◽  
Latent Tuberculosis ◽  
Tuberculin Test ◽  
P Value ◽  
Cross Sectional ◽  
Increased Risk ◽  
Significant Difference

Background: Rheumatoid arthritis (RA) patients receiving receive anti-TNF agents are at increased risk of reactivation of latent tuberculosis infection (LTBI). The tuberculin skin test (TST) is widely used to screen LTBI and providing preventive treatment, in an effort to meet the WHO target of a 90% reduction in TB by 2035. Objectives: To determine the proportion of TST conversion among RA patients after 1 year of anti-TNF treatment and association of positive TST result with patients’ socio-demographic characteristics and medical history. Methods: This community-based cross-sectional study was conducted at the Department of Rheumatology of Marjan Teaching Hospital in Iraq, for a period of 1 year. Patients with RA/and spondyloarthropathy, and who received anti-TNF therapy for >1 year, underwent TST. Their demographic data and medical history were also obtained. All statistical analysis was performed using SPSS (Version 20) and, p < 0.05 was considered as a sign. Data from the baseline and 1 year follow-up was subjected to the Kolmogorov-Smirnov test to determine whether they were normally distributed. Chi-Square test used to test significance of TST among etanrecept and infliximab at the end of the study. Results: A total of 96 patients were enrolled, including 55 (57.3%) males and 41 (42.3%) females with an average age of 41.1, and mostly 68 (70.8%) from Babylon Governorate of Iraq. A total of 40 (41.7%) patients had rheumatoid arthritis alone, and the remaining 56 (58.3%) had a comorbidity of spondyloarthropathy. Majority of the patients 65 (67.7%) received the biological agent infliximab, while 31 (32.3%) patients received Etanercept for RA for a period of 1 year. There was a statistically significant decreasing in the median ESR and disease activity  from the baseline to the end of the study (p-value <0.01). There was no significant difference in TST results based on gender or age. Both infliximab and etanercept were significantly associated with a decreasing  in ESR and disease activity Conclusion: This study has shown that there was very low TST conversion among RA patients after 1 year of anti-TNF treatment and, age and gender were not associated with TST.

scholarly journals Prevalence of High Epworth Sleepiness Scale Scores in a Rural Population

2012 ◽  
Vol 19 (2) ◽  
pp. e10-e14 ◽  
Author(s):  
P Pahwa ◽  
CP Karunanayake ◽  
L Hagel ◽  
JA Gjevre ◽  
D Rennie ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Medical History ◽  
Daytime Sleepiness ◽  
Rural Population ◽  
Epworth Sleepiness Scale ◽  
Binary Logistic Regression ◽  
Binary Logistic Regression Analysis ◽  
Physical Factors ◽  
Obstructive Sleep ◽  
Family Medical History

BACKGROUND: Increased daytime sleepiness is an important symptom of obstructive sleep apnea (OSA). OSA is frequently underdiagnosed, and the Epworth Sleepiness Scale (ESS) can be a useful tool in alerting physicians to a potential problem involving OSA.OBJECTIVE: To measure the prevalence and determinants of daytime sleepiness measured using the ESS in a rural community population.METHODS: A community survey was conducted to examine the risk factors associated with ESS in a rural population in 154 households comprising 283 adults. Questionnaire information was obtained regarding physical factors, social factors, general medical history, family medical history, ESS score, and self-reported height and weight. Multivariable binary logistic regression analysis based on the generalized estimating equations approach to account for clustering within households was used to predict the relationship between a binary ESS score outcome (normal or abnormal) and a set of explanatory variables.RESULTS: The population included 140 men (49.5%) and 143 women (50.5%) with an age range of 18 to 97 years (mean [± SD] 52.0±14.9 years). The data showed that 79.2% of the study participants had an ESS score in the normal range (0 to 10) and 20.8% had an ESS score >10, which is considered to be abnormal or high sleepiness. Multivariable regression analysis revealed that obesity was significantly associated with an abnormal or high sleepiness score on the ESS (OR 3.40 [95% CI 1.31 to 8.80).CONCLUSION: High levels of sleepiness in this population were common. Obesity was an important risk factor for high ESS score.

scholarly journals A Study of Surgical Complications of Ventilation Tube Insertion in Children in Central Iran

2020 ◽  
Vol 11 (3) ◽  
Author(s):  
Mostafa Vahedian ◽  
Amrollah Salimi ◽  
Omid Garkaz ◽  
Seyedeh Tasnim Abdi ◽  
Somayeh Donyadideh ◽  
...  
Keyword(s):  
Medical History ◽  
Surgical Complications ◽  
Ventilation Tube ◽  
Tube Insertion ◽  
Childhood Diseases ◽  
Chi Square ◽  
Historical Cohort ◽  
Family Medical History ◽  
Significant Difference ◽  
Chi Square Test

Background: Middle ear inflammation and fluid accumulation are one of the most common childhood diseases. Untreated or chronic ear inflammation can lead to more serious complications, including hearing loss, eardrum rupture, adhesive otitis media, tympanosclerosis, temporal bone necrosis, and cholesteatoma. Ventilation tube insertion is one of the best treatments to cure these diseases. Objectives: This aimed to observe children suffering from ear inflammation who were candidates for VT insertion surgery and study surgical complications. Methods: A historical cohort study was performed, and 205 VT surgeries were studied. Demographic information of children (like age, sex, and family medical history) was gathered through their medical records and probable complications, including otorrhea, tympanosclerosis, atrophy, and eardrum rupture were noticed through medical examinations and interviews. Data were analyzed using descriptive statistics, chi-square test, independent t-test, Fisher’s exact, and Mann-Whitney U-test. Results: The results showed that 57% of surgery cases were boys, and 43% were girls, both having no family medical history. Serous otitis with tonsillar hypertrophy was reported in 200 cases (97.6%), which had concurrent adenoidectomy or adenotonsillectomy. The frequency of otorrhea, tympanosclerosis, atrophy, perforation, and serous otitis recurrence was 2%, 12.2%, 6.8%, 1.5%, and 14.1%, respectively. Serous otitis recurrence was reported in 3.9% of cases with T-tube insertion. Conclusions: The findings of this study show no significant difference in surgical complications between the two groups of girls and boys. But studying the relationship between the age of patients and the timing of surgery shows that the mean age of girls is significantly higher.

scholarly journals Branchio-oto-renal syndrome: a clinical case

2019 ◽  
Vol 25 (1) ◽  
pp. 5
Author(s):  
Xavier Lagarde ◽  
Mathilde Fenelon ◽  
Jean Christophe Fricain
Keyword(s):  
Medical History ◽  
Rare Disease ◽  
Genetic Study ◽  
Clinical Case ◽  
Autosomal Dominant ◽  
Clinical Criteria ◽  
Dermatology Clinic ◽  
Family Medical History ◽  
The Family ◽  
Renal Abnormalities

Observation: A 19-week-old patient seen in an oral dermatology clinic had small labial commissures pits associated with auricular abnormalities. Similar clinical elements were found in the family medical history. A diagnosis of branchio-oto-renal syndrome (BOR) was quickly evoked. Commentary: BOR syndrome is a rare disease. This autosomal dominant pathology is characterized by facial lesions and renal abnormalities. Diagnosis is based on many clinical criteria. An optional genetic study can sometimes assist in diagnosis.

Genome Fundamentals

2016 ◽  
Author(s):  
Michael Snyder
Keyword(s):  
Heart Disease ◽  
Medical History ◽  
Family Medical History

When we visit the doctor, we are commonly asked to fill out a questionnaire about our family medical history, including major diseases such as cancer and heart disease experienced by our parents, siblings, and children. This is a rough way of gauging our risk...

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