scholarly journals 1661P Antitumor efficacy and immune profiling of the mouse ortholog of nemvaleukin alfa, a novel engineered IL-2 fusion protein, in an orthotopic mouse model of small cell lung cancer alone or in combination with standard chemotherapy

2021 ◽  
Vol 32 ◽  
pp. S1169
Author(s):  
Y. Pan ◽  
H. Zhang ◽  
T. Chen ◽  
H. Ding ◽  
H. Han ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Mouse Model ◽  
Fusion Protein ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Standard Chemotherapy ◽  
Orthotopic Mouse Model ◽  
Immune Profiling

An orthotopic mouse model of small cell lung cancer reflects the clinical course in patients

2016 ◽  
Vol 33 (7) ◽  
pp. 651-660 ◽  
Author(s):  
Sanaz Taromi ◽  
Gian Kayser ◽  
Dominik von Elverfeldt ◽  
Wilfried Reichardt ◽  
Friederike Braun ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Mouse Model ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Clinical Course ◽  
Small Cell ◽  
Small Cell Lung ◽  
Orthotopic Mouse Model

scholarly journals Anticancer Activity of ZnO Nanoparticles against Human Small-Cell Lung Cancer in an Orthotopic Mouse Model

2019 ◽  
Vol 19 (2) ◽  
pp. 502-512 ◽  
Author(s):  
Ryosuke Tanino ◽  
Yoshihiro Amano ◽  
Xuexia Tong ◽  
Rong Sun ◽  
Yukari Tsubata ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Mouse Model ◽  
Small Cell Lung Cancer ◽  
Anticancer Activity ◽  
Cell Lung Cancer ◽  
Zno Nanoparticles ◽  
Small Cell ◽  
Small Cell Lung ◽  
Orthotopic Mouse Model

PO-33 - Heparin suppresses progression of small cell lung cancer (SCLC) in an orthotopic mouse model

2016 ◽  
Vol 140 ◽  
pp. S188 ◽  
Author(s):  
S. Taromi ◽  
J. Catusse ◽  
D.v. Elverfeldt ◽  
W. Reichardt ◽  
B. Ledig ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Mouse Model ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Orthotopic Mouse Model

scholarly journals Identification of a potent kinase inhibitor targeting EML4-ALK fusion protein in non-small cell lung cancer

MedChemComm ◽  
2017 ◽  
Vol 8 (10) ◽  
pp. 1914-1918
Author(s):  
Lian-Xiang Luo ◽  
Ying Li ◽  
Yu-Zhen Niu ◽  
Yu-Wei Wang ◽  
Qian-Qian Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Fusion Protein ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Kinase Inhibitor ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancers ◽  
Alk Inhibitor

Herein, we reported 5067-0952, a potent ALK inhibitor with pharmacological efficacy in non-small cell lung cancers harboring the ALK fusion oncogene.

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