Synthesis of functionally graded bioactive glass-apatite multistructures on Ti substrates by pulsed laser deposition

Pulsed laser deposition was used to obtain functionally graded bioactive glass coatings on titanium substrates. An UV KrF* (λ=248 nm, τ>7 ns) excimer laser was used for the multi-pulse irradiation of the targets. The depositions were performed in oxygen while keeping substrate temperature at 400°C. We used sintered glass targets in the system SiO2-Na2O-K2O-CaO-MgOP2O5 that differed in SiO2 content, which was either 57 wt.% (6P57) or 61 wt.% (6P61). A glass 6P61 was used as the first layer in direct contact with the metallic substrate, while the outer bioactive layer was made of glass 6P57. Both the bioactive coatings and the bulk glasses were analyzed by Fourier transform infrared spectrometry (FTIR), grazing incidence X-ray diffraction (GIXRD), and scanning electron microscopy (SEM). The FTIR spectra of the glass powders and glass coatings showed the main vibration modes of the Si-O-Si groups. GIXRD analysis confirmed that the glass coatings had an amorphous structure. The SEM micrographs of the glass coatings showed the films to consist of droplets with diameters ranging from 0.2 to 5 μm. SEM was used to determine the rate of apatite formation on the coating when exposed to simulated body fluid (SBF) solution for 7 days. We demonstrated that pulsed laser deposition leads to good glass-metal adhesion on the substrate and well attached bioactive particles on the surface. We consider therefore this method appropriate for forming implants that can develop an apatite layer after immersion in SBF.

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Pulsed laser deposition of magnesium-containing bioactive glass film on porous Ti–6Al–4V substrate pretreated by micro-arc oxidation

Vacuum ◽

10.1016/j.vacuum.2015.12.005 ◽

2016 ◽

Vol 125 ◽

pp. 48-55 ◽

Cited By ~ 26

Author(s):

J. Ma ◽

C.Z. Wang ◽

C.L. Ban ◽

C.Z. Chen ◽

H.M. Zhang

Keyword(s):

Bioactive Glass ◽

Pulsed Laser Deposition ◽

Pulsed Laser ◽

Laser Deposition ◽

Glass Film ◽

Porous Ti ◽

Micro Arc Oxidation

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Fabricating functionally graded films with designed gradient profiles using pulsed laser deposition

Journal of Applied Physics ◽

10.1063/1.4803692 ◽

2013 ◽

Vol 113 (17) ◽

pp. 174910 ◽

Cited By ~ 2

Author(s):

Yoo Jai Won ◽

Hyungson Ki

Keyword(s):

Pulsed Laser Deposition ◽

Pulsed Laser ◽

Functionally Graded ◽

Laser Deposition

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Borate and Silicate Bioactive Glass Coatings Prepared by Nanosecond Pulsed Laser Deposition

Coatings ◽

10.3390/coatings10111105 ◽

2020 ◽

Vol 10 (11) ◽

pp. 1105

Author(s):

Julietta V. Rau ◽

Angela De Bonis ◽

Mariangela Curcio ◽

Katharina Schuhladen ◽

Katia Barbaro ◽

...

Keyword(s):

Thin Films ◽

Bioactive Glass ◽

Pulsed Laser Deposition ◽

Osteogenic Differentiation ◽

Borate Glass ◽

Pulsed Laser ◽

Laser Deposition ◽

Alizarin Red ◽

Nanosecond Pulsed Laser ◽

Biological Tests

Silicate (13-93) and borate (13-93-B3) bioactive glass coatings were successfully deposited on titanium using the nanosecond Pulsed Laser Deposition technique. The coatings’ microstructural characteristics, compositions and morphologies were examined by a number of physico-chemical techniques. The deposited coatings retain the same functional groups of the targets, are a few microns thick, amorphous, compact and crack free. Their surface is characterized by the presence of micrometric and nanometric particles. The surface topography, investigated by Atomic Force Microscopy, is characterized by spherical or ellipsoidal particles of the 0.2–3 μm size range for the 13-93 silicate bioactive glass film and of the 0.1–1 µm range for the 13-93-B3 borate bioactive glass coating. Equine adipose tissue-derived mesenchymal stem cells (ADMSCs) were applied for biological tests and the osteogenic differentiation activity of cells on the deposited coatings was studied after ADMSCs growth in osteogenic medium and staining with Alizarin Red. Cytocompatibility and osteogenic differentiation tests have shown that thin films retain the biocompatibility properties of the target silicate and borate glass, respectively. On the other hand, no antibacterial activity of the borate glass films was observed, suggesting that ion doping is advisable to inhibit bacterial growth on the surface of borate glass thin films.

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