An isoflavone metabolite reduces arterial stiffness and blood pressure in overweight men and postmenopausal women

2007 ◽  
Vol 192 (1) ◽  
pp. 184-189 ◽  
Author(s):  
Paul Nestel ◽  
Akihiko Fujii ◽  
Lei Zhang
2001 ◽  
Vol 38 (2) ◽  
pp. 506-513 ◽  
Author(s):  
Douglas R Seals ◽  
Hirofumi Tanaka ◽  
Christopher M Clevenger ◽  
Kevin D Monahan ◽  
Mary Jo Reiling ◽  
...  

2014 ◽  
Vol 17 (3) ◽  
pp. 15-21
Author(s):  
I V Barinova ◽  
Z N Blankova ◽  
N S Aslanyan ◽  
F T Ageev ◽  
O Yu Ryabtseva ◽  
...  

The study shows that addition of statins to osteoporotic therapy in postmenopausal women with different cardiovascular risk beside desired hypolipidemic effect and reduction of arterial stiffness also elevates BMD at femoral neck by 4,9% from the baseline (p<0.05). Bisphosphonates therapy in postmenopausal women gives additional reduction of central systolic arterial pressure of 4.1 mm Hg with the tendency to improvement in the arterial stiffness. The dynamics of aortal stiffness was correlated with changers in intensity of bone remodeling (for N-terminal propeptides of type I procollagen (P1NP) p =0.47, p=0.019; for carboxyl-terminal telopeptide of collagen type I (CITP1) p=0.40, p=0.05) as well as systolic blood pressure (r=0.52, p=0.008). Conclusions. Bisphosphonate therapy and its combination with statins may influence the on parameters of blood pressure and aortic stiffness in women with postmenopausal osteoporosis.


2017 ◽  
Vol 20 (2) ◽  
pp. 46-51
Author(s):  
Svetlana Yu. Tsarenok ◽  
Vladimir V. Gorbunov ◽  
Tatiana A. Aksenova

Aim: to evaluate the data of the central aortic pressure and arterial stiffness during the daily monitoring procedure in postmenopausal women with osteoporosis. Methods: 79 postmenopausal women (age from 57 to 78) were examined. All patients were divided into two groups: the first group consisted of 36 women with osteoporosis, the second group consisted of 43 women – control group. A daily monitoring of central aortic pressure and arterial stiffness were performed all women by the apparatus BPLab v.3.2. Results: increase of the mean daily of systolic, diastolic and mean aortic pressure was found out in women with osteoporosis. The main data of arterial stiffness (PWV, ASI, AASI, PPA) were higher in this group of women. The direct correlation between the data of central aortic blood pressure, arterial stiffness and presence of osteoporotic fractures and their number, as well as indicators of absolute ten-year risk of osteoporotic fractures and hip fracture was revealed. Pathological profiles of systolic pressure in aortae were more frequent in patients with osteoporosis. The type of hyperdispers was predominant. Conclusions: the results obtained may indicate a possible relationship between cardiovascular diseases and osteoporosis.


2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 153-154 ◽  
Author(s):  
Arturo Figueroa ◽  
Songyoung Park ◽  
Marcos A. Sanchez-Gonzalez ◽  
Dae Y. Seo ◽  
Young H. Baek

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