Tumor necrosis factor (TNF) superfamily members 10 and 12 are associated with the metabolic health status of morbid obese patients

2018 ◽  
Vol 275 ◽  
pp. e75-e76
Author(s):  
I. Doulamis ◽  
P. Konstantopoulos ◽  
A. Tzani ◽  
A. Antoranz ◽  
A. Daskalopoulou ◽  
...  
Keyword(s):  
Health Status ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Metabolic Health ◽  
Obese Patients ◽  
Tnf Superfamily ◽  
Morbid Obese ◽  
Necrosis Factor

scholarly journals Serum Levels of Tumor Necrosis Factor-α Are Increased in Obese Patients with Noninsulin-Dependent Diabetes Mellitus1

1998 ◽  
Vol 83 (3) ◽  
pp. 859-862 ◽  
Author(s):  
Akira Katsuki ◽  
Yasuhiro Sumida ◽  
Shuichi Murashima ◽  
Kazuya Murata ◽  
Yoshihiro Takarada ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Serum Levels ◽  
Obese Patients ◽  
Factor Α ◽  
Necrosis Factor

scholarly journals The Tumor Necrosis Factor Superfamily of Cytokines in the Inflammatory Myopathies: Potential Targets for Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Boel De Paepe ◽  
Kim K. Creus ◽  
Jan L. De Bleecker
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Current Knowledge ◽  
Inflammatory Diseases ◽  
Inflammatory Myopathies ◽  
Necrosis Factor Alpha ◽  
Tnf Superfamily ◽  
Sporadic Inclusion Body Myositis ◽  
Factor Alpha ◽  
Necrosis Factor

The idiopathic inflammatory myopathies (IM) represent a heterogeneous group of autoimmune diseases, of which dermatomyositis (DM), polymyositis (PM), and sporadic inclusion body myositis (IBM) are the most common. The crucial role played by tumor necrosis factor alpha (TNFα) in the IM has long been recognized. However, so far, 18 other members of the TNF superfamily have been characterized, and many of these have not yet received the attention they deserve. In this paper, we summarize current findings for all TNF cytokines in IM, pinpointing what we know already and where current knowledge fails. For each TNF family member, possibilities for treating inflammatory diseases in general and the IM in particular are explored.

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