scholarly journals Muscle mechanoreflex overactivity in hypertension: A role for centrally-derived nitric oxide

2015 ◽  
Vol 188 ◽  
pp. 58-63 ◽  
Author(s):  
Scott A. Smith ◽  
Anna K. Leal ◽  
Megan N. Murphy ◽  
Ryan M. Downey ◽  
Masaki Mizuno
2012 ◽  
Vol 97 (12) ◽  
pp. 1292-1304 ◽  
Author(s):  
Anna K. Leal ◽  
Megan N. Murphy ◽  
Gary A. Iwamoto ◽  
Jere H. Mitchell ◽  
Scott A. Smith

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


2001 ◽  
Vol 28 (5-6) ◽  
pp. 459-462
Author(s):  
Pini Orbach ◽  
Charles E Wood ◽  
Maureen Keller-Wood
Keyword(s):  

2001 ◽  
Vol 120 (5) ◽  
pp. A684-A684
Author(s):  
I DANIELS ◽  
I MURRAY ◽  
W GODDARD ◽  
R LONG

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