Characterization of the inhibitor-binding site in mitochondrial NADH-Ubiquinone oxidoreductase (complex I) using fenpyroximate analogues

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2012.06.169 ◽

2012 ◽

Vol 1817 ◽

pp. S59-S60

Author(s):

M. Murai ◽

Y. Shiraishi ◽

N. Sakiyama ◽

H. Miyoshi

Keyword(s):

Binding Site ◽

Complex I ◽

Inhibitor Binding ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Characterization of the Inhibitor Binding Site in Mitochondrial NADH−Ubiquinone Oxidoreductase by Photoaffinity Labeling Using a Quinazoline-Type Inhibitor†

Biochemistry ◽

10.1021/bi8019977 ◽

2009 ◽

Vol 48 (4) ◽

pp. 688-698 ◽

Author(s):

Masatoshi Murai ◽

Koji Sekiguchi ◽

Takaaki Nishioka ◽

Hideto Miyoshi

Keyword(s):

Binding Site ◽

Photoaffinity Labeling ◽

Inhibitor Binding ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Synthesis and Characterization of New Piperazine-Type Inhibitors for Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)†

Biochemistry ◽

10.1021/bi8010362 ◽

2008 ◽

Vol 47 (40) ◽

pp. 10816-10826 ◽

Author(s):

Naoya Ichimaru ◽

Masatoshi Murai ◽

Nobuyuki Kakutani ◽

Junko Kako ◽

Atsushi Ishihara ◽

...

Keyword(s):

Complex I ◽

Synthesis And Characterization ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Characterization of assembly intermediates of NADH: Ubiquinone oxidoreductase (complex I) accumulated in Neurospora mitochondria by gene disruption

Journal of Molecular Biology ◽

10.1016/0022-2836(92)90519-p ◽

1992 ◽

Vol 227 (4) ◽

pp. 1032-1042 ◽

Author(s):

Uwe Nehls ◽

Thorsten Friedrich ◽

Andreas Schmiede ◽

Tomoko Ohnishi ◽

Hanns Weiss

Keyword(s):

Complex I ◽

Gene Disruption ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Characterization of the 25-kilodalton subunit of the energy-transducing NADH-ubiquinone oxidoreductase of Paracoccus denitrificans: sequence similarity to the 24-kilodalton subunit of the flavoprotein fraction of mammalian complex I

Biochemistry ◽

10.1021/bi00099a027 ◽

1991 ◽

Vol 30 (35) ◽

pp. 8678-8684 ◽

Author(s):

Xuemin Xu ◽

Akemi Matsuno-Yagi ◽

Takao Yagi

Keyword(s):

Complex I ◽

Paracoccus Denitrificans ◽

Sequence Similarity ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Immunocytochemical Characterization of the Mitochondrially Encoded ND1 Subunit of Complex I (NADH : Ubiquinone Oxidoreductase) in Rat Brain

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2000.0750383.x ◽

2000 ◽

Vol 75 (1) ◽

pp. 383-392 ◽

Author(s):

Edward H. Pettus ◽

Ranjita Betarbet ◽

Barbara Cottrell ◽

Douglas C. Wallace ◽

Vijay Madyastha ◽

...

Keyword(s):

Rat Brain ◽

Complex I ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Three-dimensional structure of bovine heart NADH: ubiquinone oxidoreductase (complex I) by electron microscopy of a single negatively stained two-dimensional crystal

10.1093/jmicro/dft082 ◽

2014 ◽

Vol 63 (2) ◽

pp. 167-174 ◽

Author(s):

Satoru Shimada ◽

Kyoko Shinzawa-Itoh ◽

Satoko Amano ◽

Yui Akira ◽

Atsuo Miyazawa ◽

...

Keyword(s):

Electron Microscopy ◽

Complex I ◽

Three Dimensional ◽

Dimensional Structure ◽

Two Dimensional ◽

Three Dimensional Structure ◽

Ubiquinone Oxidoreductase ◽

Bovine Heart ◽

Nadh Ubiquinone Oxidoreductase ◽

Dimensional Crystal

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A small isoform of NADH: ubiquinone oxidoreductase (complex I) without mitochondrially encoded subunits is made in chloramphenicol-treated Neurospora crassa

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1989.tb14629.x ◽

1989 ◽

Vol 180 (1) ◽

pp. 173-180 ◽

Author(s):

Thorsten FRIEDRICH ◽

Gotz HOFHAUS ◽

Wolfgang ISE ◽

Uwe NEHLS ◽

Beate SCHMITZ ◽

...

Keyword(s):

Neurospora Crassa ◽

Complex I ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase ◽

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[1] Generation and characterization of NADH: Ubiquinone oxidoreductase mutants in Neurospora crassa

Methods in Enzymology - Mitochondrial Biogenesis and Genetics Part A ◽

10.1016/0076-6879(95)60126-0 ◽

1995 ◽

pp. 3-14 ◽

Author(s):

Ulrich Schulte ◽

Hanns Weiss

Keyword(s):

Neurospora Crassa ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase

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Two binding sites for naturally occurring inhibitors in mitochondrial and bacterial NADH: ubiquinone oxidoreductase (Complex I)

Biochemical Society Transactions ◽

10.1042/bst0220226 ◽

1994 ◽

Vol 22 (1) ◽

pp. 226-230 ◽

Author(s):

Thorsten Friedrich ◽

Tomoko Ohnishi ◽

Edgar Forche ◽

Brigitte Kunze ◽

Rolf Jansen ◽

...

Keyword(s):

Binding Sites ◽

Complex I ◽

Ubiquinone Oxidoreductase ◽

Naturally Occurring ◽

Nadh Ubiquinone Oxidoreductase

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The respiratory complex I in yeast: Isolation of a geneNUO51 coding for the nucleotide-binding subunit of NADH: Ubiquinone oxidoreductase from the obligately aerobic yeastYarrowia lipolytica

Folia Microbiologica ◽

10.1007/bf02817616 ◽

2000 ◽

Vol 45 (5) ◽

pp. 429-433 ◽

Author(s):

A. Ryčovská ◽

R. Szabo ◽

L'. Tomáška ◽

J. Nosek

Keyword(s):

Complex I ◽

Nucleotide Binding ◽

Respiratory Complex ◽

Ubiquinone Oxidoreductase ◽

Nadh Ubiquinone Oxidoreductase ◽

Respiratory Complex I ◽

Yeast Isolation ◽

Binding Subunit

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