The pro-inflammatory cytokine TNF-α regulates the expression of the serotonin transporter (SERT) gene in primary astrocytes and the C6 glioma cell line

2010 ◽  
Vol 24 ◽  
pp. S70-S71 ◽  
Author(s):  
S. Malynn ◽  
A.C. Torres ◽  
P. Moynagh ◽  
J. Haase
1989 ◽  
Vol 48 (3) ◽  
pp. 359
Author(s):  
G. M. Zientek ◽  
A. Frankfurter ◽  
C. D. Katsetos ◽  
M. M. Herman

2009 ◽  
Vol 37 (2) ◽  
pp. 503-510 ◽  
Author(s):  
X-D Zhou ◽  
X-Y Wang ◽  
F-J Qu ◽  
Y-H Zhong ◽  
X-D Lu ◽  
...  

Biochemistry ◽  
2005 ◽  
Vol 44 (29) ◽  
pp. 9924-9935 ◽  
Author(s):  
Evgeny Levin ◽  
Arumugam Premkumar ◽  
Leo Veenman ◽  
Wilfried Kugler ◽  
Svetlana Leschiner ◽  
...  

1990 ◽  
Vol 72 (5) ◽  
pp. 782-785 ◽  
Author(s):  
Justin D. Cohen ◽  
H. Ian Robins ◽  
Manucher J. Javid

✓ The cytotoxic, antiproliferative, and radiosensitizing effects of thymidine (a nucleoside metabolite) were studied using the C6 glioma cell line in vitro. Radiosensitization by a combination of thymidine and 41.8°C hyperthermia was also evaluated. Thymidine concentrations above 100 µg/ml completely inhibited C6 proliferation while concentrations of 100 to 1000 µg/ml (for up to 24 hours) decreased C6 cell survival to as little as 7.4% compared to untreated control cells. Radiosensitivity was enhanced by the administration of thymidine alone (400 µg/ml × 24 hours before irradiation); sensitization by 41.8°C hyperthermia alone (1 hour ending immediately before irradiation) was less pronounced. Thymidine and hyperthermia together produced greater radiosensitization than did heat alone or thymidine alone. These data support the further investigation of thymidine as a neuro-oncology radiosensitizer.


2008 ◽  
Vol 44 (7) ◽  
pp. 280-289 ◽  
Author(s):  
Gang Shen ◽  
Fang Shen ◽  
Zhuojin Shi ◽  
Weiguo Liu ◽  
Weiwei Hu ◽  
...  

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