Individual differences in cytokine concentrations and depressive-like behavior are associated with tumor onset in a mammary tumor model

2011 ◽  
Vol 25 ◽  
pp. S209
Author(s):  
L.M. Pyter ◽  
B.J. Prendergast
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Begüm Utz ◽  
Rita Turpin ◽  
Johanna Lampe ◽  
Jeroen Pouwels ◽  
Juha Klefström

Abstract Breast cancer is the most common form of cancer in women. Despite significant therapeutic advances in recent years, breast cancer also still causes the greatest number of cancer-related deaths in women, the vast majority of which (> 90%) are caused by metastases. However, very few mouse mammary cancer models exist that faithfully recapitulate the multistep metastatic process in human patients. Here we assessed the suitability of a syngrafting protocol for a Myc-driven mammary tumor model (WAP-Myc) to study autochthonous metastasis. A moderate but robust spontaneous lung metastasis rate of around 25% was attained. In addition, increased T cell infiltration was observed in metastatic tumors compared to donor and syngrafted primary tumors. Thus, the WAP-Myc syngrafting protocol is a suitable tool to study the mechanisms of metastasis in MYC-driven breast cancer.


2008 ◽  
Vol 68 (5) ◽  
pp. 1407-1416 ◽  
Author(s):  
Lionel W. Hebbard ◽  
Michèle Garlatti ◽  
Lawrence J.T. Young ◽  
Robert D. Cardiff ◽  
Robert G. Oshima ◽  
...  

2020 ◽  
Vol 55 (10) ◽  
pp. 657-665 ◽  
Author(s):  
Alexandre Helbert ◽  
Mathew Von Wronski ◽  
Delphine Colevret ◽  
Catherine Botteron ◽  
Frederic Padilla ◽  
...  

2011 ◽  
Vol 6 (4) ◽  
pp. 403-411 ◽  
Author(s):  
Franziska Kramer Birkved ◽  
Alicja Mortensen ◽  
José L. Peñalvo ◽  
Rikke H. Lindecrona ◽  
Ilona Kryspin Sørensen

2010 ◽  
Vol 289 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Melissa Mastroianni ◽  
Soyoung Kim ◽  
Young Chul Kim ◽  
Amanda Esch ◽  
Caroline Wagner ◽  
...  

2018 ◽  
Vol 213 ◽  
pp. 31-37 ◽  
Author(s):  
Hassan Muhammad Yankuzo ◽  
Yusha’u Shu’aibu Baraya ◽  
Zulkarnain Mustapha ◽  
Kah Keng Wong ◽  
Nik Soriani Yaacob

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