Unique haplotype in exon 3 of cone opsin mRNA affects splicing of its precursor, leading to congenital color vision defect

2012 ◽  
Vol 424 (1) ◽  
pp. 152-157 ◽  
Author(s):  
Hisao Ueyama ◽  
Sanae Muraki-Oda ◽  
Shinichi Yamade ◽  
Shoko Tanabe ◽  
Takahiro Yamashita ◽  
...  
2019 ◽  
Vol 9 (4) ◽  
pp. 69-71
Author(s):  
Anadi Khatri ◽  
Bal Kumar K.C ◽  
Sudhir Gautam ◽  
Muna Kharel

Background: Color vision tests are routinely performed and are mandatory in most part of the world. However, in Nepal and many other developing countries, color vision may often be overlooked. We evaluated a possible burden of color vision in a group of patients who were specifically evaluated for a color vision defects. This study evalutes the awareness of color vision defect among the patients evaluated and highlights the importance of the color vision evaluation. Methods: A sequential group of 73 people from August to September 2017 specifically evalu­ated for color vision defect for recruitment of government employment were evaluated. Ishi­harapseudo-isochromatic plates and Farnsworth-Munsell Dichotomous D-15 test were used for screening. Mean and Standard deviation were used for descriptive analysis of the data. Results: Fifty-seven were male and sixteen were female. The mean age was 23 years (SD ± 3.7). On evaluation of the color vision defect, 9 (12.3%) were found to have total color vision defect (achromatopsia), 3 (4%)-red-green defect and 1(1%) with blue red defect. None of the patients had undergone color vision test at eye hospital previously. There were 4 patients who were registered drivers who had color vision defect. Conclusions: Color vision is an important part of the vision. It should not be ignored.All of the patients evaluated were found to be unware of their condition. Early detection of color vision defects in individuals, if possible, at school level can help them to determine their careers and future endeavors at early stage.


2004 ◽  
Vol 21 (3) ◽  
pp. 449-453 ◽  
Author(s):  
JEFFERY K. HOVIS ◽  
SHANKARAN RAMASWAMY ◽  
MATTHEW ANDERSON

The repeatability of the D-15 color-vision test is considered to be excellent. However, this conclusion is based on a subject pool which contained a large percentage of color-normals. This type of sampling could bias the repeatability results because color-normals rarely fail the test. Furthermore, color-normals usually do not perform the D-15 in the clinical setting. To establish the repeatability of the D-15 for a relevant clinical population, we examined the D-15 results from two different sessions for 116 subjects who had a congenital red–green color-vision defect. The kappa coefficient for intersession agreement indicated that approximately 84% of the subjects obtained the same pass/fail results at both sessions. The type of defect was repeatable on approximately 80% of the subjects. Although the repeatability of the D-15 for color-defective subjects was good, it was lower than the near-perfect agreement reported previously. The coefficients of repeatability for the crossings show that if a person makes less than five crossings then the test should be administered again in order to ensure that the test result is repeatable.


2017 ◽  
Vol 94 (5) ◽  
pp. 626-629 ◽  
Author(s):  
Eunoo Bak ◽  
Hee Kyung Yang ◽  
Jeong-Min Hwang

1995 ◽  
Vol 39 (5) ◽  
pp. 403-408 ◽  
Author(s):  
James Ravin ◽  
James G. Ravin ◽  
Nancy Anderson ◽  
Philippe Lanthony

Author(s):  
Sudha Shakya

Humans have many types of sensations such as sight, hearing, touch, smell, taste etc. They originate from stimulants, which a person receives from their external environment, stimulate the stimulating senses i.e. eye, ear, skin, nose and tongue, and produce different sensations. According to Eiseneck (1972), "sensation is a mental process that is no longer divisible." It is produced by external stimuli that affect the senses, and its intensity depends on the stimulus, and its properties depend on the nature of the senses. Apart from these five sensations, there are other sensations such as incidental sensation, static sensation and motion sensation. मानव में कई प्रकार की संवेदनाएं होती हैं जैसे दृष्टि, श्रवण, स्पर्श, गंध, स्वाद आदि। इनकी उत्पत्ति उद्दीपकों से होती है, जिसे व्यक्ति अपने बाह्य पर्यावरण से ग्रहण करता है, यह उद्दीपक ज्ञानेन्द्रियों अर्थात आंख, कान, त्वचा, नाक और जिव्हा को उद्दीप्त करते हैं, और विभिन्न संवेदना को उत्पन्न करते हैं। आइजनेक (1972) के अनुसार ‘‘ संवेदना एक मानसिक प्रक्रम है जो आगे विभाजन योग्य नहीं होता। यह ज्ञानेन्द्रियों को प्रभावित करने वाली बाह्य उत्तेजना द्वारा उत्पादित होता है, तथा इसकी तीव्रता उत्तेजना पर निर्भर करती है, और इसके गुण ज्ञानेन्द्रिय की प्रकृति पर निर्भर करते हैं। इन पांच संवेदनाओं के अतिरिक्त अन्य संवेदना भी है जैसे आंगिक संवेदना, स्थैतिक संवेदना तथा गति संवेदना।


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