Dipeptidyl peptidase-4 inhibitor ameliorates early renal injury through its anti-inflammatory action in a rat model of type 1 diabetes

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2013.12.049 ◽

2014 ◽

Vol 443 (3) ◽

pp. 828-833 ◽

Author(s):

Ryo Kodera ◽

Kenichi Shikata ◽

Tetsuharu Takatsuka ◽

Kaori Oda ◽

Satoshi Miyamoto ◽

...

Keyword(s):

Type 1 Diabetes ◽

Rat Model ◽

Renal Injury ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Anti Inflammatory ◽

Inflammatory Action

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The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes

Life Sciences ◽

10.1016/j.lfs.2019.116738 ◽

2019 ◽

Vol 234 ◽

pp. 116738 ◽

Author(s):

Catarina Marques ◽

Andreia Gonçalves ◽

Patrícia Manuela Ribeiro Pereira ◽

Daniela Almeida ◽

Beatriz Martins ◽

...

Keyword(s):

Oxidative Stress ◽

Type 1 Diabetes ◽

Rat Model ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Glomerular Lesions

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Faculty Opinions recommendation of Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8727957.11798054 ◽

2011 ◽

Author(s):

Kyong Soo Park ◽

Soo Heon Kwak

Keyword(s):

Type 1 Diabetes ◽

Blood Glucose ◽

Blood Glucose Level ◽

Rat Model ◽

Renal Injury ◽

Receptor Agonist ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Inflammatory Action

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Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis

Hepatology Research ◽

10.1111/hepr.12860 ◽

2017 ◽

Vol 47 (12) ◽

pp. 1317-1328 ◽

Author(s):

Yasushi Okura ◽

Tadashi Namisaki ◽

Kei Moriya ◽

Mitsuteru Kitade ◽

Kosuke Takeda ◽

...

Keyword(s):

Angiotensin Ii ◽

Rat Model ◽

Combined Treatment ◽

Dipeptidyl Peptidase ◽

Receptor Blocker ◽

Diabetic Rat ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Diabetic Rat Model

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Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes

Diabetologia ◽

10.1007/s00125-010-2028-x ◽

2011 ◽

Vol 54 (4) ◽

pp. 965-978 ◽

Author(s):

R. Kodera ◽

K. Shikata ◽

H. U. Kataoka ◽

T. Takatsuka ◽

S. Miyamoto ◽

...

Keyword(s):

Type 1 Diabetes ◽

Blood Glucose ◽

Blood Glucose Level ◽

Rat Model ◽

Renal Injury ◽

Receptor Agonist ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Inflammatory Action

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Oral therapy for type 1 diabetes mellitus using a novel immunomodulator, FTY720 (fingolimod), in combination with sitagliptin, a dipeptidyl peptidase-4 inhibitor, examined in non-obese diabetic mice

Journal of Diabetes Investigation ◽

10.1111/j.2040-1124.2012.00218.x ◽

2012 ◽

Vol 3 (5) ◽

pp. 441-448 ◽

Author(s):

Takumi Tsuji ◽

Yuya Yoshida ◽

Tetsuro Fujita ◽

Takeyuki Kohno

Keyword(s):

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Type 1 Diabetes Mellitus ◽

Oral Therapy ◽

Dipeptidyl Peptidase ◽

Diabetic Mice ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Faculty Opinions recommendation of Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8727957.9242055 ◽

2011 ◽

Author(s):

Carolyn Ecelbarger

Keyword(s):

Type 1 Diabetes ◽

Blood Glucose ◽

Blood Glucose Level ◽

Rat Model ◽

Renal Injury ◽

Receptor Agonist ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Inflammatory Action

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Possible Long-Term Efficacy of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, for Slowly Progressive Type 1 Diabetes (SPIDDM) in the Stage of Non-Insulin-Dependency: An Open-Label Randomized Controlled Pilot Trial (SPAN-S)

Diabetes Therapy ◽

10.1007/s13300-017-0299-7 ◽

2017 ◽

Vol 8 (5) ◽

pp. 1123-1134 ◽

Author(s):

Takuya Awata ◽

Akira Shimada ◽

Taro Maruyama ◽

Yoichi Oikawa ◽

Nobuyuki Yasukawa ◽

...

Keyword(s):

Type 1 Diabetes ◽

Pilot Trial ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Randomized Controlled ◽

Progressive Type ◽

Dipeptidyl Peptidase 4 Inhibitor

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Abstract #292 Atypical Case of Type 1 Diabetes Mellitus Treated with Basal Insulin and Dipeptidyl Peptidase-4 Inhibitor

Endocrine Practice ◽

10.1016/s1530-891x(20)47137-x ◽

2018 ◽

Vol 24 ◽

pp. 78-79

Author(s):

Shivani Vekaria ◽

Juman Takeddin ◽

Xiangbing Wang

Keyword(s):

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Type 1 Diabetes Mellitus ◽

Basal Insulin ◽

Dipeptidyl Peptidase ◽

Atypical Case ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome

Hypertension Research ◽

10.1038/hr.2014.53 ◽

2014 ◽

Vol 37 (7) ◽

pp. 629-635 ◽

Author(s):

Hironori Nakagami ◽

Zhengda Pang ◽

Takashi Shimosato ◽

Toshinori Moritani ◽

Hitomi Kurinami ◽

...

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Endothelial Dysfunction ◽

Rat Model ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose

PLoS ONE ◽

10.1371/journal.pone.0143941 ◽

2015 ◽

Vol 10 (11) ◽

pp. e0143941 ◽

Author(s):

Salheen M. Salheen ◽

Usha Panchapakesan ◽

Carol A. Pollock ◽

Owen L. Woodman

Keyword(s):

Endothelial Function ◽

Plasma Glucose ◽

Dipeptidyl Peptidase ◽

Diabetic Rats ◽

Mesenteric Arteries ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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