Orotic acid protects pancreatic β cell by p53 inactivation in diabetic mouse model

2021 ◽  
Author(s):  
Yohei Fushimura ◽  
Atsushi Hoshino ◽  
Satoru Furukawa ◽  
Takashi Nakagawa ◽  
Tomohiro Hino ◽  
...  
Keyword(s):  
Mouse Model ◽  
Orotic Acid ◽  
Diabetic Mouse ◽  
Pancreatic Β Cell ◽  
Β Cell ◽  
P53 Inactivation

scholarly journals MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation

EBioMedicine ◽  
2017 ◽  
Vol 15 ◽  
pp. 163-172 ◽  
Author(s):  
Sohei Tsukita ◽  
Tetsuya Yamada ◽  
Kei Takahashi ◽  
Yuichiro Munakata ◽  
Shinichiro Hosaka ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Mouse Model ◽  
Pancreatic Β Cell ◽  
Β Cell

scholarly journals Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes

Diabetes ◽  
2012 ◽  
Vol 62 (1) ◽  
pp. 44-48 ◽  
Author(s):  
Patrick F. Antkowiak ◽  
Brian K. Stevens ◽  
Craig S. Nunemaker ◽  
Marcia McDuffie ◽  
Frederick H. Epstein
Keyword(s):  
Magnetic Resonance Imaging ◽  
Type 1 Diabetes ◽  
Magnetic Resonance ◽  
Mouse Model ◽  
Cell Mass ◽  
Pancreatic Β Cell ◽  
Resonance Imaging ◽  
Β Cell

scholarly journals Early administration of dapagliflozin preserves pancreatic β‐cell mass through a legacy effect in a mouse model of type 2 diabetes

2018 ◽  
Vol 10 (3) ◽  
pp. 577-590 ◽  
Author(s):  
Ayumi Kanno ◽  
Shun‐ichiro Asahara ◽  
Mao Kawamura ◽  
Ayuko Furubayashi ◽  
Shoko Tsuchiya ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Mouse Model ◽  
Cell Mass ◽  
Pancreatic Β Cell ◽  
Β Cell ◽  
Early Administration ◽  
Legacy Effect

scholarly journals Generation and Characterization of a Novel Mouse Model That Allows Spatiotemporal Quantification of Pancreatic β-Cell Proliferation

Diabetes ◽  
2020 ◽  
Vol 69 (11) ◽  
pp. 2340-2351 ◽  
Author(s):  
Shinsuke Tokumoto ◽  
Daisuke Yabe ◽  
Hisato Tatsuoka ◽  
Ryota Usui ◽  
Muhammad Fauzi ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Mouse Model ◽  
Pancreatic Β Cell ◽  
Β Cell

scholarly journals Administration of mulberry leaves maintains pancreatic β-cell mass in obese/type 2 diabetes mellitus mouse model

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Patlada Suthamwong ◽  
Manabu Minami ◽  
Toshiaki Okada ◽  
Nonomi Shiwaku ◽  
Mai Uesugi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Mouse Model ◽  
Cell Mass ◽  
Pancreatic Β Cell ◽  
Β Cell ◽  
Mulberry Leaves

scholarly journals B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic β-cell carcinogenesis

Oncogene ◽  
2008 ◽  
Vol 27 (35) ◽  
pp. 4779-4787 ◽  
Author(s):  
I Sobczak ◽  
G Galabova-Kovacs ◽  
I Sadzak ◽  
A Kren ◽  
G Christofori ◽  
...  
Keyword(s):  
Mouse Model ◽  
Tumor Progression ◽  
Pancreatic Β Cell ◽  
Β Cell ◽  
Erk Activation

scholarly journals A bioluminescent mouse model of pancreatic β-cell carcinogenesis

2010 ◽  
Vol 31 (8) ◽  
pp. 1465-1474 ◽  
Author(s):  
Adrian Zumsteg ◽  
Karin Strittmatter ◽  
Daniela Klewe-Nebenius ◽  
Helena Antoniadis ◽  
Gerhard Christofori
Keyword(s):  
Mouse Model ◽  
Pancreatic Β Cell ◽  
Β Cell

Combination of TS-021 with metformin improves hyperglycemia and synergistically increases pancreatic β-cell mass in a mouse model of type 2 diabetes

Life Sciences ◽  
2011 ◽  
Vol 89 (17-18) ◽  
pp. 662-670 ◽  
Author(s):  
Atsushi Tajima ◽  
Takashi Hirata ◽  
Kazuo Taniguchi ◽  
Yukiko Kondo ◽  
Sota Kato ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Mouse Model ◽  
Cell Mass ◽  
Pancreatic Β Cell ◽  
Β Cell

scholarly journals Intermittent Hypoxia Exacerbates Pancreatic β-Cell Dysfunction in A Mouse Model of Diabetes Mellitus

SLEEP ◽  
2013 ◽  
Vol 36 (12) ◽  
pp. 1849-1858 ◽  
Author(s):  
Shariq I. Sherwani ◽  
Carolyn Aldana ◽  
Saif Usmani ◽  
Christopher Adin ◽  
Sainath Kotha ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Mouse Model ◽  
Intermittent Hypoxia ◽  
Pancreatic Β Cell ◽  
Β Cell ◽  
Cell Dysfunction
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