nonobese diabetic mouse
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Assessing Immune Responses in the Nonobese Diabetic Mouse Model of Type 1 Diabetes

2020 ◽  
pp. 269-289
Author(s):  
Terri C. Thayer ◽  
Dimitri Kakabadse ◽  
Joanne Boldison ◽  
F. Susan Wong
Keyword(s):  
Type 1 Diabetes ◽  
Mouse Model ◽  
Immune Responses ◽  
Diabetic Mouse ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic

scholarly journals The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model

2019 ◽  
Vol 21 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Janice M. Nieves-Bonilla ◽  
Badr Kiaf ◽  
Cornelia Schuster ◽  
Stephan Kissler
Keyword(s):  
Type 1 Diabetes ◽  
Mouse Model ◽  
Candidate Gene ◽  
Disease Risk ◽  
Diabetic Mouse ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic ◽  
Diabetes Candidate Gene

scholarly journals Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse

The Prostate ◽  
2019 ◽  
Vol 79 (9) ◽  
pp. 980-993 ◽  
Author(s):  
LaTayia M. Aaron‐Brooks ◽  
Takeshi Sasaki ◽  
Renee E. Vickman ◽  
Lin Wei ◽  
Omar E. Franco ◽  
...  
Keyword(s):  
T Cell ◽  
Diabetic Mouse ◽  
Prostatic Hyperplasia ◽  
Cell Infiltration ◽  
Nonobese Diabetic Mouse ◽  
T Cell Infiltration ◽  
Nonobese Diabetic

scholarly journals Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model

2019 ◽  
Vol 5 (5) ◽  
pp. 2631-2646 ◽  
Author(s):  
Jamal S. Lewis ◽  
Joshua M. Stewart ◽  
Gregory P. Marshall ◽  
Matthew R. Carstens ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Dendritic Cells ◽  
Mouse Model ◽  
Diabetic Mouse ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic

scholarly journals 2431

2017 ◽  
Vol 1 (S1) ◽  
pp. 37-37
Author(s):  
Andrea Lin ◽  
Clayton Mathews ◽  
Michael Haller ◽  
Todd Brusko ◽  
Mark Atkinson ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Type 1 Diabetes ◽  
T Regulatory Cells ◽  
Immune Cell ◽  
Diabetic Mouse ◽  
Regulatory Cells ◽  
Flow Cytometry Analysis ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic

OBJECTIVES/SPECIFIC AIMS: Understand the immunomodulatory effects of anti-thymocyte globulin (ATG) and granulocyte colony stimulating factor (G-CSF) on type 1 diabetes patients using samples and in the preclinical model, the nonobese diabetic mouse. METHODS/STUDY POPULATION: Flow cytometry analysis of phase 1 peripheral blood samples treatment of nonobese diabetic mouse with ATG and GCSF and flow cytometry analysis of immune organs (spleen, lymph nodes, blood, bone marrow). RESULTS/ANTICIPATED RESULTS: Changes in both innate and adaptive immune cell subsets including plasmacytoid dendritic cells, naive, memory, effector CD4+ and CD8+ T-cells, and CD4+ T-regulatory cells and CD8+ T-regulatory cells DISCUSSION/SIGNIFICANCE OF IMPACT: Understanding of immune cell targets for immunotherapy in new-onset type 1 diabetes patients.

scholarly journals CD8 T cells contribute to lacrimal gland pathology in the nonobese diabetic mouse model of Sjögren syndrome

2017 ◽  
Vol 95 (8) ◽  
pp. 684-694 ◽  
Author(s):  
Jennifer Y Barr ◽  
Xiaofang Wang ◽  
David K Meyerholz ◽  
Scott M Lieberman
Keyword(s):  
T Cells ◽  
Mouse Model ◽  
Lacrimal Gland ◽  
Cd8 T Cells ◽  
Diabetic Mouse ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic

scholarly journals Reg3g overexpression promotes β cell regeneration and induces immune tolerance in nonobese-diabetic mouse model

2015 ◽  
Vol 99 (6) ◽  
pp. 1131-1140 ◽  
Author(s):  
Fei Xia ◽  
Hui Cao ◽  
Jiao Du ◽  
Xiulan Liu ◽  
Yang Liu ◽  
...  
Keyword(s):  
Mouse Model ◽  
Immune Tolerance ◽  
Diabetic Mouse ◽  
Cell Regeneration ◽  
Nonobese Diabetic Mouse ◽  
Β Cell ◽  
Nonobese Diabetic
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