Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

Biochemical Pharmacology ◽

10.1016/j.bcp.2010.03.012 ◽

2010 ◽

Vol 80 (5) ◽

pp. 683-689 ◽

Author(s):

Chunling Yi ◽

Jasna Maksimoska ◽

Ronen Marmorstein ◽

Joseph L. Kissil

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Therapeutic Targets ◽

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Discovery of selective, small-molecule inhibitors of RNA complexes—II. Self-splicing group I intron ribozyme

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(97)00065-5 ◽

1997 ◽

Vol 5 (6) ◽

pp. 1185-1195 ◽

Author(s):

Houng-Yau Mei ◽

Mei Cui ◽

Shannon M. Lemrow ◽

Anthony W. Czarnik

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Group I Intron ◽

Group I ◽

Rna Complexes ◽

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Exploring the biological space of FOXO regulation: discovery of therapeutic targets and small molecule inhibitors for anticancer therapy

New Biotechnology ◽

10.1016/j.nbt.2009.06.010 ◽

2009 ◽

Vol 25 ◽

pp. S3

Author(s):

W. Link

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Therapeutic Targets ◽

Anticancer Therapy

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Abstract 3843: Rational selection of combinatorial therapeutic targets for melanoma identified by synthetic lethal screening with small molecule inhibitors

10.1158/1538-7445.am10-3843 ◽

2010 ◽

Author(s):

Devin G. Roller ◽

Kerrington R. Molhoek ◽

Craig L. Slingluff ◽

Michael J. Weber ◽

Daniel Gioeli

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Therapeutic Targets ◽

Rational Selection ◽

Synthetic Lethal ◽

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Abstract B14: Synergy of small-molecule inhibitors in cutaneous T-cell lymphoma cells: A discovery tool to define new therapeutic targets

10.1158/1535-7163.pms-b14 ◽

2013 ◽

Author(s):

Meghan Bliss-Moreau ◽

Weimin Xiao ◽

Preethi Gunaratne ◽

Nancy L. Krett ◽

Steven T. Rosen

Keyword(s):

T Cell ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Cell Lymphoma ◽

Therapeutic Targets ◽

T Cell Lymphoma ◽

Cutaneous T Cell Lymphoma ◽

Lymphoma Cells ◽

New Therapeutic Targets

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AAA ATPases as Therapeutic Targets: Structure, Functions, and Small-Molecule Inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113446 ◽

2021 ◽

pp. 113446

Author(s):

Gang Zhang ◽

Shan Li ◽

Kai-Wen Cheng ◽

Tsui-Fen Chou

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Therapeutic Targets ◽

Structure Functions ◽

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From molecular diagnostics to molecular targeted therapy with natural product small molecule inhibitors in oral squamous cell carcinoma

Planta Medica ◽

10.1055/s-2007-986722 ◽

2007 ◽

Vol 73 (09) ◽

Author(s):

VB Konkimalla ◽

VL Suhas ◽

NR Chandra ◽

E Gebhart ◽

T Efferth

Keyword(s):

Squamous Cell Carcinoma ◽

Targeted Therapy ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Natural Product ◽

Molecular Diagnostics ◽

Small Molecule ◽

Squamous Cell ◽

Molecular Targeted Therapy ◽

Small Molecule Inhibitors

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Faculty Opinions recommendation of Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004750.54854 ◽

2002 ◽

Author(s):

Carol Otey

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors

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Faculty Opinions recommendation of Identification of small molecule inhibitors of anthrax lethal factor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1016978.201559 ◽

2004 ◽

Author(s):

Kristina Downing

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Lethal Factor ◽

Anthrax Lethal Factor

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Faculty Opinions recommendation of Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017973.285766 ◽

2005 ◽

Author(s):

George Perry

Keyword(s):

Small Molecule ◽

Amyloid Beta ◽

Small Molecule Inhibitors

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Faculty Opinions recommendation of High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023153.264839 ◽

2005 ◽

Author(s):

Robert Kelley

Keyword(s):

T Cell ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

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