Effects of the novel vascular targeting agent MDS-11P on tumor vascularity and its antitumor activity

Biochemical Pharmacology ◽

10.1016/j.bcp.2011.08.024 ◽

2011 ◽

Vol 82 (12) ◽

pp. 1832-1842 ◽

Author(s):

Zhi-Ting Deng ◽

Teng Feng ◽

Peng Wang ◽

Xin Qi ◽

Xue-Hong Chen ◽

...

Keyword(s):

Antitumor Activity ◽

Vascular Targeting ◽

The Novel ◽

Tumor Vascularity ◽

Vascular Targeting Agent

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Preclinical evaluation of the antitumour activity of the novel vascular targeting agent Oxi 4503

European Journal of Cancer ◽

10.1016/s0959-8049(02)80764-x ◽

2002 ◽

Vol 38 ◽

pp. S39

Keyword(s):

Antitumour Activity ◽

Vascular Targeting ◽

The Novel ◽

Preclinical Evaluation ◽

Vascular Targeting Agent

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Abstract 4381: The novel direct-acting vascular targeting agent NGR-TNF exertsin vivoantitumor activity by inducing endothelial and tumor cell death in the absence of proangiogenic bone-marrow derived cell recruitment

10.1158/1538-7445.am2012-4381 ◽

2012 ◽

Author(s):

Paola Di Matteo ◽

Christina Hackl ◽

Christopher Jedeszko ◽

Simona Porcellini ◽

Barbara Valentinis ◽

...

Keyword(s):

Bone Marrow ◽

Vascular Targeting ◽

The Novel ◽

Tumor Cell Death ◽

Cell Recruitment ◽

Direct Acting ◽

Vascular Targeting Agent

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A phase I safety and PK study of the novel vascular targeting agent (VTA), Exherin, in patients with refractory solid tumors stratified according to N-cadherin expression

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3078 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3078-3078

Author(s):

D. J. Jonker ◽

L. Avruch ◽

D. J. Stewart ◽

R. Goel ◽

G. Goss ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Vascular Targeting ◽

The Novel ◽

Vascular Targeting Agent

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A phase I safety and PK study of the novel vascular targeting agent (VTA), Exherin, in patients with refractory solid tumors stratified according to N-cadherin expression

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3078 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3078-3078

Author(s):

D. J. Jonker ◽

L. Avruch ◽

D. J. Stewart ◽

R. Goel ◽

G. Goss ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Vascular Targeting ◽

The Novel ◽

Vascular Targeting Agent

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A phase I study of the novel molecularly targeted vascular targeting agent, Exherin (ADH-1), shows activity in some patients with refractory solid tumors stratified according to N-cadherin expression

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3038 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3038-3038 ◽

Author(s):

D. J. Jonker ◽

D. J. Stewart ◽

R. Goel ◽

L. Avruch ◽

G. Goss ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Phase I Study ◽

Vascular Targeting ◽

The Novel ◽

Vascular Targeting Agent

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OXI 4503 a novel vascular targeting agent: Effects on bloodflow and antitumor activity in comparison to Combretastatin A-4 phosphate

European Journal of Cancer ◽

10.1016/s0959-8049(02)80778-x ◽

2002 ◽

Vol 38 ◽

pp. S43

Keyword(s):

Antitumor Activity ◽

Vascular Targeting ◽

Vascular Targeting Agent

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Sensitization of Tumor-Associated Endothelial Cell Apoptosis by the Novel Vascular-Targeting Agent ZD6126 in Combination with Cisplatin

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-04-1171 ◽

2004 ◽

Vol 10 (22) ◽

pp. 7671-7676 ◽

Author(s):

Hisatsugu Goto ◽

Seiji Yano ◽

Yuka Matsumori ◽

Hirohisa Ogawa ◽

David C. Blakey ◽

...

Keyword(s):

Endothelial Cell ◽

Cell Apoptosis ◽

Vascular Targeting ◽

The Novel ◽

Endothelial Cell Apoptosis ◽

Vascular Targeting Agent

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Enhancement of radiation therapy by the novel vascular targeting agent ZD6126

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/s0360-3016(02)02742-6 ◽

2002 ◽

Vol 53 (1) ◽

pp. 164-171 ◽

Author(s):

Dietmar W Siemann ◽

Amyn M Rojiani

Keyword(s):

Radiation Therapy ◽

Vascular Targeting ◽

The Novel ◽

Vascular Targeting Agent

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The novel vascular-targeting agent ZD6126 shows enhanced anti-tumour efficacy in large, bulky tumours

European Journal of Cancer ◽

10.1016/s0959-8049(02)80769-9 ◽

2002 ◽

Vol 38 ◽

pp. S40

Keyword(s):

Vascular Targeting ◽

The Novel ◽

Vascular Targeting Agent

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Faculty Opinions recommendation of Phase I clinical evaluation of weekly administration of the novel vascular-targeting agent, ZD6126, in patients with solid tumors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13790.471274 ◽

2006 ◽

Author(s):

Jeffrey Evans

Keyword(s):

Phase I ◽

Solid Tumors ◽

Clinical Evaluation ◽

Vascular Targeting ◽

The Novel ◽

Weekly Administration ◽

Vascular Targeting Agent

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