Gene therapy process change evaluation framework: transient transfection and stable producer cell line comparison

2021 ◽  
pp. 108202
Author(s):  
Ruxandra-Maria Comisel ◽  
Bo Kara ◽  
Frederick H Fiesser ◽  
Suzanne S Farid
Keyword(s):  
Gene Therapy ◽  
Cell Line ◽  
Transient Transfection ◽  
Evaluation Framework ◽  
Therapy Process ◽  
Process Change ◽  
Producer Cell Line ◽  
Producer Cell

A Stable Producer Cell Line for the Manufacture of a Lentiviral Vector for Gene Therapy of Parkinson's Disease

2011 ◽  
Vol 22 (3) ◽  
pp. 357-369 ◽  
Author(s):  
Hannah J. Stewart ◽  
Liang Fong-Wong ◽  
Iain Strickland ◽  
Daniel Chipchase ◽  
Michelle Kelleher ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Gene Therapy ◽  
Parkinson's Disease ◽  
Cell Line ◽  
Lentiviral Vector ◽  
Producer Cell Line ◽  
Producer Cell

scholarly journals 458. Development of a Stable Producer Cell Line for Scalable Lentiviral Vector Production for Gene Therapy of Hemoglobinopathie

2016 ◽  
Vol 24 ◽  
pp. S182
Author(s):  
Sarah Slauson ◽  
Amelia Thomas ◽  
Byoung Ryu ◽  
Melissa Bonner ◽  
Gretchen Lewis ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Cell Line ◽  
Lentiviral Vector ◽  
Producer Cell Line ◽  
Producer Cell

A Sclerostin Super-Producer Cell Line Derived from the Human Cell Line SaOS-2: A New Tool for the Study of the Molecular Mechanisms Driving Sclerostin Expression

2014 ◽  
Vol 95 (2) ◽  
pp. 194-199 ◽  
Author(s):  
Flor M. Pérez-Campo ◽  
Carolina Sañudo ◽  
Jesús Delgado-Calle ◽  
Jana Arozamena ◽  
María T. Zarrabeitia ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Cell ◽  
Molecular Mechanisms ◽  
Human Cell Line ◽  
Producer Cell Line ◽  
Producer Cell

Efficient Production of rAAV in a Perfusion Bioreactor Using an ELEVECTA® Stable Producer Cell Line

2021 ◽  
Vol 41 (S2) ◽  
pp. S23-S23
Author(s):  
Juliana Coronel ◽  
Aishwarya Patil ◽  
Ahmad Al-Dali ◽  
Thomas Braβ ◽  
Nicole Faust ◽  
...  
Keyword(s):  
Cell Line ◽  
Perfusion Bioreactor ◽  
Efficient Production ◽  
Producer Cell Line ◽  
Producer Cell

In UteroGene Delivery by Intraamniotic Injection of a Retroviral Vector Producer Cell Line in a Nonhuman Primate Model

2001 ◽  
Vol 12 (15) ◽  
pp. 1857-1865 ◽  
Author(s):  
Michael Bennett ◽  
Henry Galan ◽  
Geoffrey Owens ◽  
Rosemary Dewey ◽  
Ronald Banks ◽  
...  
Keyword(s):  
Cell Line ◽  
Nonhuman Primate ◽  
Retroviral Vector ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
Producer Cell Line ◽  
Producer Cell
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