Nanostructured hyaluronic acid-based hydrogels encapsulating synthetic/ natural hybrid nanogels as promising wound dressings

2022 ◽  
pp. 108341
Author(s):  
Alina Gabriela Rusu ◽  
Aurica P. Chiriac ◽  
Loredana Elena Nita ◽  
Alina Ghilan ◽  
Daniela Rusu ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Wound Dressings ◽  
Natural Hybrid

Hyaluronic acid electrospinning: Challenges, applications in wound dressings and new perspectives

2021 ◽  
Vol 173 ◽  
pp. 251-266
Author(s):  
Karine Cappuccio Castro ◽  
Maria Gabriela Nogueira Campos ◽  
Lucia Helena Innocentini Mei
Keyword(s):  
Hyaluronic Acid ◽  
Wound Dressings

scholarly journals New Hyaluronic Acid/Polyethylene Oxide-Based Electrospun Nanofibers: Design, Characterization and In Vitro Biological Evaluation

Polymers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1291
Author(s):  
Oana Maria Ionescu ◽  
Arn Mignon ◽  
Andreea Teodora Iacob ◽  
Natalia Simionescu ◽  
Luminita Georgeta Confederat ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Ethylene Oxide ◽  
Transmission Rate ◽  
Biological Evaluation ◽  
Wound Dressings ◽  
Calendula Officinalis ◽  
Active Components ◽  
Poly Ethylene Oxide ◽  
Nanofiber Membranes ◽  
Poly Ethylene

Natural compounds have been used as wound-healing promoters and are also present in today’s clinical proceedings. In this research, different natural active components such as propolis, Manuka honey, insulin, L-arginine, and Calendula officinalis infusion were included into hyaluronic acid/poly(ethylene)oxide-based electrospun nanofiber membranes to design innovative wound-dressing biomaterials. Morphology and average fiber diameter were analyzed by scanning electron microscopy. Chemical composition was proved by Fourier transform infrared spectroscopy, which indicated successful incorporation of the active components. The nanofiber membranes with propolis and Calendula officinalis showed best antioxidant activity, cytocompatibility, and antimicrobial properties against pathogen strains Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa and had an average diameter of 217 ± 19 nm with smooth surface aspect. Water vapor transmission rate was in agreement with the range suitable for preventing infections or wound dehydration (~5000 g/m2 24 h). Therefore, the developed hyaluronic acid/poly(ethylene)oxide nanofibers with additional natural components showed favorable features for clinical use as wound dressings.

scholarly journals Hyaluronic Acid-Based Scaffolds as Potential Bioactive Wound Dressings

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2102
Author(s):  
Sibusiso Alven ◽  
Blessing A. Aderibigbe
Keyword(s):  
Hyaluronic Acid ◽  
Healing Process ◽  
Wound Dressings ◽  
Microbial Pathogens ◽  
Wound Healing Process ◽  
Therapeutic Outcomes ◽  
Inflammatory Drugs ◽  
Bioactive Agents ◽  
Treatment Of Wounds ◽  
Negative Factors

The negative factors that result in delayed and prolonged wound healing process include microbial pathogens, excess wound exudates, underlying conditions, smoking, obesity, etc. Most of the currently used wound dressings demonstrate an inadequate capacity to treat wounds resulting from the factors mentioned above. The commonly used wound dressings include hydrogels, films, hydrocolloids, foams, fibers, sponges, dermal patches, bandages, etc. These wound dressings can be loaded with various types of bioactive agents (e.g., antibiotics, nanoparticles, anti-inflammatory drugs, etc.) to improve their therapeutic outcomes. Biopolymers offer interesting properties suitable for the design of wound dressings. This review article will be based on hyaluronic-acid-based scaffolds loaded with therapeutic agents for the treatment of wounds.

Outcomes of the Use of Hyaluronic Acid-Based Wound Dressings for the Treatment of Partial-Thickness Facial Burns

2019 ◽  
Author(s):  
Reyyan Yildirim ◽  
Ali Guner ◽  
Arif Burak Cekic ◽  
Mehmet Arif Usta ◽  
Mehmet Ulusahin ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Wound Dressings ◽  
Partial Thickness ◽  
Facial Burns

Wound Dressings Based on Chitosans and Hyaluronic Acid for the Release of Chlorhexidine Diacetate in Skin Ulcer Therapy

2007 ◽  
Vol 12 (4) ◽  
pp. 415-422 ◽  
Author(s):  
Silvia Rossi ◽  
Marzia Marciello ◽  
Giuseppina Sandri ◽  
Franca Ferrari ◽  
Maria Cristina Bonferoni ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Skin Ulcer ◽  
Wound Dressings ◽  
Ulcer Therapy

Hyaluronic acid/Na-alginate films as topical bioactive wound dressings

2018 ◽  
Vol 109 ◽  
pp. 101-109 ◽  
Author(s):  
A. Abou-Okeil ◽  
H.M. Fahmy ◽  
M.K. El-Bisi ◽  
O.A. Ahmed-Farid
Keyword(s):  
Hyaluronic Acid ◽  
Wound Dressings

scholarly journals Hyaluronic acid in wound dressings

2020 ◽  
Vol 66 (4) ◽  
pp. 191
Author(s):  
Hernán Cortes ◽  
Isaac H. Caballero-Florán ◽  
Néstor Mendoza-Muñoz ◽  
Elva N. Córdova-Villanueva ◽  
Lidia Escutia-Guadarrama ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Wound Dressings

scholarly journals THE POSSIBILITY OF USING THE POLYMER FOR THE TREATMENT OF FULL NANOBIOCOMPOSITES SKIN DEFECTS

2017 ◽  
Vol 19 (1) ◽  
pp. 46-50
Author(s):  
Evgeniy V Zinov'ev ◽  
Marat S Asadulaev ◽  
Denis V Kostyakov ◽  
Kamil F Osmanov ◽  
Roman G Stoyanovskiy ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Reparative Regeneration ◽  
Wound Dressings ◽  
Skin Defect ◽  
Skin Wounds ◽  
Mechanical Reproduction ◽  
Significant Acceleration ◽  
Hyaluronic Acid Hydrogel ◽  
Regeneration Processes

The results of the experimental evaluation of the effectiveness of wound dressings based on chitosan nanofibres and copolyamide with treatment of full mechanical skin wounds. To develop their own original technique of mechanical reproduction all layers of the skin wounds in the experiment. It was found that application of wound dressings based on aliphatic copolyamide and chitosan can significantly optimize reparative regeneration processes in the area all layers of the skin defect, thus reducing the time stated scab rejection and wound healing, respectively, 7.5 and 11.2 days (p 0,05). It is shown that the use of coatings based on hyaluronic acid hydrogel is also accompanied by a significant acceleration in the zone histogenesis all layers of the blemishes, shortening the healing period of the final 21% (p 0,05) (4 figs, 1 table, bibliography: 14 refs).

Sign in / Sign up

Export Citation Format

Share Document