Iron oxide core oil-in-water emulsions as a multifunctional nanoparticle platform for tumor targeting and imaging

Combination of nanotechnology, biochemistry, chemistry and biotechnology provides the opportunity to design unique nanoparticles for tumor targeting, drug delivery, medical imaging and biosensing. Nanoparticles conjugated with biomolecules such as antibodies, peptides, vitamins and aptamer can resolve current challenges including low accumulation, internalization and retention at the target site in cancer diagnosis and therapy through active targeting. In this review, we focus on different strategies for conjugation of biomolecules to nanoparticles such as inorganic nanoparticles (iron oxide, gold, silica and carbon nanoparticles), liposomes, lipid and polymeric nanoparticles and their application in tumor targeting.

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Magnetic properties of FeCo-iron oxide core–shell nanoparticles investigated through first order reversal studies

Applied Physics A ◽

10.1007/s00339-020-04176-z ◽

2021 ◽

Vol 127 (1) ◽

Author(s):

G. Antilen Jacob ◽

R. Justin Joseyphus

Keyword(s):

Magnetic Properties ◽

Iron Oxide ◽

Core Shell ◽

Shell Nanoparticles ◽

First Order ◽

Iron Oxide Core ◽

Core Shell Nanoparticles

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Determining the size of nanoparticles in the example of magnetic iron oxide core-shell systems

Journal of Physics Conference Series ◽

10.1088/1742-6596/885/1/012007 ◽

2017 ◽

Vol 885 ◽

pp. 012007 ◽

Cited By ~ 3

Author(s):

Maciej Jarzębski ◽

Mikołaj Kościński ◽

Tomasz Białopiotrowicz

Keyword(s):

Iron Oxide ◽

Core Shell ◽

Magnetic Iron Oxide ◽

Iron Oxide Core

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Synthesis of Monodisperse Iron Oxide and Iron/Iron Oxide Core/Shell Nanoparticles via Iron-Oleylamine Complex

Journal of Nanoscience and Nanotechnology ◽

10.1166/jnn.2006.338 ◽

2006 ◽

Vol 6 (7) ◽

pp. 2135-2140 ◽

Cited By ~ 8

Author(s):

S. Yu ◽

G. M. Chow

Keyword(s):

Iron Oxide ◽

Core Shell ◽

Shell Nanoparticles ◽

Iron Iron ◽

Iron Oxide Core ◽

Core Shell Nanoparticles

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The Effect of Nanoparticle Coating on the Thermal Conductivity of Nanofluids

MRS Proceedings ◽

10.1557/proc-1207-n07-05 ◽

2009 ◽

Vol 1207 ◽

Author(s):

Michael John Fornasiero ◽

Diana-Andra Borca-Tasciuc

Keyword(s):

Thermal Conductivity ◽

Iron Oxide ◽

Effective Thermal Conductivity ◽

Colloidal Suspensions ◽

Maxwell Model ◽

Carrier Fluid ◽

Coated Nanoparticles ◽

Transient Hot Wire Technique ◽

Potential Applications ◽

Iron Oxide Core

AbstractNanofluids are engineered colloidal suspensions of nanometer-sized particles in a carrier fluid and are receiving significant attention because of their potential applications in heat transfer area. Theoretical investigations have shown that the enhanced thermal conductivity observed in nanofluids is due to nanoparticle clustering and networking. This provides a low resistance path to the heat flowing through the fluid. However, the surface coating of the nanoparticles, which is often used to provide stable dispersion over the long term, may act as a thermal barrier, reducing the effective thermal conductivity of the nanofluid. Moreover, nanofluids with the same type of nanoparticles may exhibit different effective thermal conductivities, depending upon the thermal properties and thickness of the coating. In this context, thermal conductivity characterization of well dispersed iron oxide nanoparticles with two different surface coatings was carried out employing the transient hot wire technique. The diameter of the iron oxide core was 35 nm and the coatings used were aminosilane and carboxymethyl-dextran (CMX) of 7nm in thickness. Preliminary results suggest that effective thermal conductivity of CMX coated nanoparticle suspensions is slightly higher than that of aminosilane coated nanoparticles. In both cases, the effective thermal conductivity is higher than that predicted by the Maxwell model for composite media.

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