Multivariate Association of Child Depression and Anxiety With Asthma Outcomes

AbstractMaternal thyroid dysfunction during pregnancy may contribute to offspring neurobehavioral disorders. In this paper, we investigate the relationship between maternal thyroid function during pregnancy and offspring depression and anxiety. Data were taken from the Avon Longitudinal Study of Parents and Children. A total of 2,920 mother-child pairs were included. Thyroid-stimulating hormone levels, free thyroxine (FT4), and thyroid peroxidase antibodies were assessed during the first trimester of pregnancy because maternal supply is the only source of thyroid hormone for the fetus during the first 12 weeks of gestation. Child symptoms of depression and anxiety were assessed using the Development and Well-Being Assessment at ages 7.5 and 15 years. The odds of presenting with depression and anxiety were estimated using the generalized estimating equation. The level of FT4 during the first trimester of pregnancy was associated with child depression combined at ages 7.5 and 15 (odds ratio = 1.21, 95% confidence interval [1.00, 1.14]. An increase of 1 standard deviation of FT4 during pregnancy increased the odds of child depression by 28% after adjustment made for potential confounders. No association was found among maternal levels of thyroid-stimulating hormone, FT4, and thyroid peroxidase antibodies and childhood anxiety. In conclusion, increased levels of FT4 during the first trimester of pregnancy appear be linked to greater risk of offspring depression.

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Group Appointments Improve Asthma Outcomes

Internal Medicine News ◽

10.1016/s1097-8690(09)70321-x ◽

2009 ◽

Vol 42 (9) ◽

pp. 25

Author(s):

KERRI WACHTER

Keyword(s):

Asthma Outcomes

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Individual Differences and Hemispheric Asymmetry While Processing Emotional Words

Journal of Individual Differences ◽

10.1027/1614-0001/a000137 ◽

2014 ◽

Vol 35 (3) ◽

pp. 137-143 ◽

Cited By ~ 1

Author(s):

Lindsay M. Niccolai ◽

Thomas Holtgraves

Keyword(s):

Individual Differences ◽

Hemispheric Asymmetry ◽

Past Research ◽

Decision Task ◽

Depression And Anxiety ◽

Hemispheric Differences ◽

Affective Valence ◽

Emotional Words ◽

Emotion Words ◽

The Right

This research examined differences in the perception of emotion words as a function of individual differences in subclinical levels of depression and anxiety. Participants completed measures of depression and anxiety and performed a lexical decision task for words varying in affective valence (but equated for arousal) that were presented briefly to the right or left visual field. Participants with a lower level of depression demonstrated hemispheric asymmetry with a bias toward words presented to the left hemisphere, but participants with a higher level of depression displayed no hemispheric differences. Participants with a lower level of depression also demonstrated a bias toward positive words, a pattern that did not occur for participants with a higher level of depression. A similar pattern occurred for anxiety. Overall, this study demonstrates how variability in levels of depression and anxiety can influence the perception of emotion words, with patterns that are consistent with past research.

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Dimensionality and Reliability Assessment of the Pain Patient Profile Questionnaire

European Journal of Psychological Assessment ◽

10.1027/1015-5759.24.1.22 ◽

2008 ◽

Vol 24 (1) ◽

pp. 22-26 ◽

Cited By ~ 1

Author(s):

Brian E. McGuire ◽

Michael J. Hogan ◽

Todd G. Morrison

Keyword(s):

Self Report ◽

Pain Patient ◽

Fit Indices ◽

Depression And Anxiety ◽

Oblique Rotation ◽

Pain Experience ◽

Patient Profile ◽

Adequate Representation ◽

Pain Patients ◽

Report Measure

Abstract. Objective: To factor analyze the Pain Patient Profile questionnaire (P3; Tollison & Langley, 1995 ), a self-report measure of emotional distress in respondents with chronic pain. Method: An unweighted least squares factor analysis with oblique rotation was conducted on the P3 scores of 160 pain patients to look for evidence of three distinct factors (i.e., Depression, Anxiety, and Somatization). Results: Fit indices suggested that three distinct factors, accounting for 32.1%, 7.0%, and 5.5% of the shared variance, provided an adequate representation of the data. However, inspection of item groupings revealed that this structure did not map onto the Depression, Anxiety, and Somatization division purportedly represented by the P3. Further, when the analysis was re-run, eliminating items that failed to meet salience criteria, a two-factor solution emerged, with Factor 1 representing a mixture of Depression and Anxiety items and Factor 2 denoting Somatization. Each of these factors correlated significantly with a subsample's assessment of pain intensity. Conclusion: Results were not congruent with the P3's suggested tripartite model of pain experience and indicate that modifications to the scale may be required.

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