Fermentative utilization of coffee mucilage using Bacillus coagulans and investigation of down-stream processing of fermentation broth for optically pure l(+)-lactic acid production

2016 ◽  
Vol 211 ◽  
pp. 398-405 ◽  
Author(s):  
Anna-Katrin Neu ◽  
Daniel Pleissner ◽  
Kerstin Mehlmann ◽  
Roland Schneider ◽  
Gloria Inés Puerta-Quintero ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Acid Production ◽  
Fermentation Broth ◽  
Lactic Acid Production ◽  
Stream Processing ◽  
Bacillus Coagulans ◽  
Optically Pure

scholarly journals Major Role of NAD-Dependent Lactate Dehydrogenases in the Production of l-Lactic Acid with High Optical Purity by the Thermophile Bacillus coagulans

2014 ◽  
Vol 80 (23) ◽  
pp. 7134-7141 ◽  
Author(s):  
Limin Wang ◽  
Yumeng Cai ◽  
Lingfeng Zhu ◽  
Honglian Guo ◽  
Bo Yu
Keyword(s):  
Lactic Acid ◽  
Lactate Dehydrogenase ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Optical Purity ◽  
Bacillus Coagulans ◽  
Lactobacillus Delbrueckii ◽  
Content Type ◽  
High Optical Purity ◽  
Optically Pure

ABSTRACTBacillus coagulans2-6 is an excellent producer of optically purel-lactic acid. However, little is known about the mechanism of synthesis of the highly optically purel-lactic acid produced by this strain. Three enzymes responsible for lactic acid production—NAD-dependentl-lactate dehydrogenase (l-nLDH; encoded byldhL), NAD-dependentd-lactate dehydrogenase (d-nLDH; encoded byldhD), and glycolate oxidase (GOX)—were systematically investigated in order to study the relationship between these enzymes and the optical purity of lactic acid.Lactobacillus delbrueckiisubsp.bulgaricusDSM 20081 (ad-lactic acid producer) andLactobacillus plantarumsubsp.plantarumDSM 20174 (adl-lactic acid producer) were also examined in this study as comparative strains, in addition toB. coagulans. The specific activities of key enzymes for lactic acid production in the three strains were characterizedin vivoandin vitro, and the levels of transcription of theldhL,ldhD, and GOX genes during fermentation were also analyzed. The catalytic activities ofl-nLDH andd-nLDH were different inl-,d-, anddl-lactic acid producers. Onlyl-nLDH activity was detected inB. coagulans2-6 under native conditions, and the level of transcription ofldhLinB. coagulans2-6 was much higher than that ofldhDor the GOX gene at all growth phases. However, for the twoLactobacillusstrains used in this study,ldhDtranscription levels were higher than those ofldhL. The high catalytic efficiency ofl-nLDH toward pyruvate and the high transcription ratios ofldhLtoldhDandldhLto the GOX gene provide the key explanations for the high optical purity ofl-lactic acid produced byB. coagulans2-6.

Lactic acid production with the supplementation of spent cells and fish wastes for the purpose of reducing impurities in fermentation broth

2007 ◽  
Vol 36 (3) ◽  
pp. 276-280 ◽  
Author(s):  
Min-Tian Gao ◽  
Makoto Hirata ◽  
Eiichi Toorisaka ◽  
Tadashi Hano
Keyword(s):  
Lactic Acid ◽  
Acid Production ◽  
Fermentation Broth ◽  
Lactic Acid Production

scholarly journals Lactic acid production from lime-treated wheat straw by Bacillus coagulans: neutralization of acid by fed-batch addition of alkaline substrate

2008 ◽  
Vol 78 (5) ◽  
pp. 751-758 ◽  
Author(s):  
Ronald H. W. Maas ◽  
Robert R. Bakker ◽  
Mickel L. A. Jansen ◽  
Diana Visser ◽  
Ed de Jong ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Wheat Straw ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Bacillus Coagulans ◽  
Fed Batch

Polymer grade l-lactic acid production from sugarcane bagasse hemicellulosic hydrolysate using Bacillus coagulans

2019 ◽  
Vol 6 ◽  
pp. 26-31 ◽  
Author(s):  
Regiane Alves de Oliveira ◽  
Roland Schneider ◽  
Carlos Eduardo Vaz Rossell ◽  
Rubens Maciel Filho ◽  
Joachim Venus
Keyword(s):  
Lactic Acid ◽  
Sugarcane Bagasse ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Bacillus Coagulans ◽  
Hemicellulosic Hydrolysate

scholarly journals Seed culture pre-adaptation of Bacillus coagulans MA-13 improves lactic acid production in simultaneous saccharification and fermentation

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Martina Aulitto ◽  
Salvatore Fusco ◽  
David Benjamin Nickel ◽  
Simonetta Bartolucci ◽  
Patrizia Contursi ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Acid Production ◽  
Simultaneous Saccharification And Fermentation ◽  
Lactic Acid Production ◽  
Bacillus Coagulans ◽  
Seed Culture ◽  
Simultaneous Saccharification

One-pot process for lactic acid production from wheat straw by an adapted Bacillus coagulans and identification of genes related to hydrolysate-tolerance

2020 ◽  
Vol 315 ◽  
pp. 123855
Author(s):  
Shuiping Ouyang ◽  
Lihua Zou ◽  
Hui Qiao ◽  
Jinjie Shi ◽  
Zhaojuan Zheng ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Wheat Straw ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Bacillus Coagulans ◽  
One Pot
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