Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents

2005 ◽  
Vol 13 (8) ◽  
pp. 2749-2757 ◽  
Author(s):  
Carlos Velázquez ◽  
P.N. Praveen Rao ◽  
Robert McDonald ◽  
Edward E. Knaus
Keyword(s):  
Nitric Oxide ◽  
Biological Evaluation ◽  
Nitric Oxide Donor ◽  
Cox 2 ◽  
Synthesis And Biological Evaluation

Selective COX-2 inhibitors. Part 2: Synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides

2008 ◽  
Vol 16 (5) ◽  
pp. 2697-2706 ◽  
Author(s):  
Shwu-Jiuan Lin ◽  
Wei-Jern Tsai ◽  
Wen-Fei Chiou ◽  
Tsang-Hsiung Yang ◽  
Li-Ming Yang
Keyword(s):  
Biological Evaluation ◽  
Cox 2 ◽  
Cox 2 Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment

2014 ◽  
Vol 22 (2) ◽  
pp. 756-761 ◽  
Author(s):  
Andrew Nortcliffe ◽  
Alexander G. Ekstrom ◽  
James R. Black ◽  
James A. Ross ◽  
Fouad K. Habib ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Nitric Oxide ◽  
Cancer Treatment ◽  
Biological Evaluation ◽  
Prostate Cancer Treatment ◽  
Synthesis And Biological Evaluation

Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors

2006 ◽  
Vol 14 (8) ◽  
pp. 2507-2517 ◽  
Author(s):  
Latifeh Navidpour ◽  
Hamed Shafaroodi ◽  
Khosrou Abdi ◽  
Mohsen Amini ◽  
Mohammad H. Ghahremani ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Cox 2 ◽  
Cox 2 Inhibitors ◽  
Synthesis And Biological Evaluation

Structure-Based Design, Synthesis, and Biological Evaluation of Indomethacin Derivatives as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors§

2007 ◽  
Vol 50 (25) ◽  
pp. 6367-6382 ◽  
Author(s):  
Shiow-Jyi Wey ◽  
Michael E. Augustyniak ◽  
Edward D. Cochran ◽  
James L. Ellis ◽  
Xinqin Fang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Biological Evaluation ◽  
Cyclooxygenase 2 ◽  
Nitric Oxide Donors ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation
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