Design, synthesis, and biological activity evaluation of (-)-6-O-desmethylantofine analogues as potent anti-cancer agents

2019 ◽  
Vol 27 (14) ◽  
pp. 3070-3081 ◽  
Author(s):  
Guifang Han ◽  
Lihua Qing ◽  
Meng Wu ◽  
Yuxiang Wang ◽  
Yuxiu Liu ◽  
...  
Keyword(s):  
Biological Activity ◽  
Design Synthesis ◽  
Activity Evaluation ◽  
Anti Cancer

Design, synthesis and biological activity evaluation of novel conjugated sialic acid and pentacyclic triterpene derivatives as anti-influenza entry inhibitors

MedChemComm ◽  
2016 ◽  
Vol 7 (10) ◽  
pp. 1932-1945 ◽  
Author(s):  
Xu Han ◽  
Yongying Shi ◽  
Longlong Si ◽  
Zibo Fan ◽  
Han Wang ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Biological Activity ◽  
Sialic Acid ◽  
Virus Entry ◽  
Pentacyclic Triterpene ◽  
Design Synthesis ◽  
Entry Inhibitors ◽  
Activity Evaluation ◽  
Virus Entry Inhibitors

A total of 24 novel sialic acid–pentacyclic triterpene conjugates were synthesized and evaluated as anti-influenza virus entry inhibitors.

Design, synthesis, and biological activity evaluation of a series of pleuromutilin derivatives with novel C14 side chains

2020 ◽  
Vol 30 (7) ◽  
pp. 126969
Author(s):  
Yun-Ge Li ◽  
Ju-Xian Wang ◽  
Guo-Ning Zhang ◽  
Mei Zhu ◽  
Xue-Fu You ◽  
...  
Keyword(s):  
Biological Activity ◽  
Side Chains ◽  
Design Synthesis ◽  
Activity Evaluation

Design, Synthesis and Biological Activity Evaluation of Novel Rho Kinase Inhibitors

2018 ◽  
Vol 38 (4) ◽  
pp. 871
Author(s):  
Yangyang Yao ◽  
Xiaoyu Liu ◽  
Feilong Yang ◽  
Ying Yang ◽  
Tianyi Yuan ◽  
...  
Keyword(s):  
Biological Activity ◽  
Kinase Inhibitors ◽  
Rho Kinase ◽  
Design Synthesis ◽  
Activity Evaluation ◽  
Rho Kinase Inhibitors

Design, synthesis and biological activity evaluation of desloratadine analogues as H1 receptor antagonists

2013 ◽  
Vol 21 (14) ◽  
pp. 4178-4185 ◽  
Author(s):  
Yan Lin ◽  
Yue Wang ◽  
Li-Feng Sima ◽  
Dong-Hua Wang ◽  
Xiao-Hui Cao ◽  
...  
Keyword(s):  
Biological Activity ◽  
H1 Receptor ◽  
Receptor Antagonists ◽  
Design Synthesis ◽  
Activity Evaluation

Design, synthesis and biological activity evaluation of novel carbazole-benzylpiperidine hybrids as potential anti Alzheimer agents

2020 ◽  
Vol 1221 ◽  
pp. 128793
Author(s):  
Batool Sadeghian ◽  
Amirhossein Sakhteman ◽  
Zeinab Faghih ◽  
Hamid Nadri ◽  
Najmeh Edraki ◽  
...  
Keyword(s):  
Biological Activity ◽  
Design Synthesis ◽  
Activity Evaluation
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