Study on calcium net absorptivity by 41Ca labeling calcium pool of rats

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S60 ◽  
Author(s):  
H. Shen ◽  
X. Ruan ◽  
S. Jiang ◽  
M. He ◽  
S. Mi ◽  
...  
Keyword(s):  
Calcium Pool

scholarly journals Persistent intracellular calcium pool depletion by thapsigargin and its influence on cell growth.

1991 ◽  
Vol 266 (36) ◽  
pp. 24690-24697 ◽  
Author(s):  
T.K. Ghosh ◽  
J.H. Bian ◽  
A.D. Short ◽  
S.L. Rybak ◽  
D.L. Gill
Keyword(s):  
Cell Growth ◽  
Intracellular Calcium ◽  
Calcium Pool

scholarly journals Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway

Oncogene ◽  
2002 ◽  
Vol 21 (17) ◽  
pp. 2623-2633 ◽  
Author(s):  
Qin He ◽  
Dong Ik Lee ◽  
Rong Rong ◽  
Myounghee Yu ◽  
Xiuquan Luo ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Death Receptor ◽  
Death Receptor 5 ◽  
Endoplasmic Reticulum Calcium ◽  
Induced Apoptosis ◽  
Calcium Pool

scholarly journals Erythrocyte calcium metabolism. Calcium exchange in normal and sickle-cell-anaemia erythrocytes

1976 ◽  
Vol 156 (3) ◽  
pp. 577-583 ◽  
Author(s):  
B F Cameron ◽  
P E Smariga
Keyword(s):  
Sickle Cell ◽  
Calcium Metabolism ◽  
Sickle Cell Anaemia ◽  
Similar Proportion ◽  
Exchange Equilibrium ◽  
Exchangeable Calcium ◽  
Calcium Loading ◽  
Calcium Exchange ◽  
Phosphate Buffered Saline ◽  
Calcium Pool

Under exchange conditions (no net increase in calcium), erythrocytes incubated in isoosmotic phosphate-buffered saline have an exchangeable calcium pool comprising about 10% of the total erythrocyte calcium. This pool reaches exchange equilibrium, for either inward-directed or outward-directed transfer of the 45Ca-exchange label, with a half-time of about 20 min. The uptake of Ca2+ requires phosphate, even under hypo-osmotic conditions, where the calcium loading expected as the cells swell is obtained only when phosphate is present. The phosphate requirement is not due to Ca2+ transport as a phosphate salt. This exchangeable-calcium pool is also present in sickle-cell-anemia erythrocytes, and comprises a similar proportion of total cellular calcium.

scholarly journals Mitogenic stimulation transiently increases the exchangeable mitochondrial calcium pool in rat thymocytes

1987 ◽  
Vol 246 (1) ◽  
pp. 173-177 ◽  
Author(s):  
P L Lakin-Thomas ◽  
M D Brand
Keyword(s):  
Concanavalin A ◽  
Mitochondrial Calcium ◽  
Mitogenic Stimulation ◽  
Exchangeable Calcium ◽  
Selective Depletion ◽  
Significant Change ◽  
Calcium Pool

Exchangeable calcium pools were measured in rat thymocytes by 45Ca labelling and selective depletion of intracellular pools with oligomycin in the presence or absence of rotenone. The mitochondrial pool increased by 150% after 3 min of treatment with the mitogen concanavalin A, and decreased to zero 10 min after mitogen addition. No significant change in the ATP-dependent pool could be detected.

scholarly journals The influence of dietary phosphorus intake on the rate of bone metabolism in sheep

1966 ◽  
Vol 20 (4) ◽  
pp. 727-732 ◽  
Author(s):  
V. R. Young ◽  
J. R. Luick ◽  
G. P. Lofgreen
Keyword(s):  
Bone Metabolism ◽  
Turnover Rates ◽  
Isotope Techniques ◽  
Dietary Phosphorus ◽  
Exchangeable Ca ◽  
Dietary Phosphorus Intake ◽  
Phosphorus Depletion ◽  
Phosphorus Intake ◽  
P Depletion ◽  
Calcium Pool

1. A combination of balance and isotope techniques was used to determine the influence of phosphorus depletion on the size of the exchangeable calcium pool and on the rates of Ca deposition in and removal from the whole skeleton of sheep. 2. The exchangeable Ca pool was reduced in size in the depleted sheep to approximately 50% of that in the controls. 3. The rates of Ca deposition in and removal from bone were reduced by P depletion and the rate of Ca transfer from the pool was reduced slightly. 4. The turnover rates of the exchangeable Ca pool and bone Ca in sheep appear to be similar to values published for man.

scholarly journals Size of the inositol 1,4,5-trisphosphate-sensitive calcium pool in guinea-pig hepatocytes

1985 ◽  
Vol 232 (2) ◽  
pp. 435-438 ◽  
Author(s):  
C W Taylor ◽  
J W Putney
Keyword(s):  
Guinea Pig ◽  
Kinetic Analysis ◽  
Protein Phosphorylation ◽  
Previous Suggestion ◽  
Inositol 1,4,5 Trisphosphate ◽  
Calcium Pool

Permeabilized hepatocytes accumulated 45Ca2+ into a non-mitochondrial pool when provided with ATP. 45Ca2+ efflux from this pool was revealed by removal of ATP with glucose and hexokinase or by inhibiting uptake with NaVO3. The effect of inositol 1,4,5-trisphosphate (IP3) on 45Ca2+ efflux from the pool was investigated. IP3 (5 microM) evoked a rapid increase in the rate of 45Ca2+ efflux. Kinetic analysis of the effect of IP3 indicated the existence of two distinct Ca2+ fractions within the pool; only one, accounting for about one-third of the ATP-dependent Ca2+ content of the pool, was responsive to IP3. The effect of IP3 on 45Ca2+ efflux from the non-mitochondrial pool does not require ATP, a finding that is inconsistent with a previous suggestion that this effect may be mediated by protein phosphorylation.

INFLUENCE OF LOW DOSE OF STEROID THERAPY ON CALCIUM ABSORPTION

1972 ◽  
Vol 69 (3) ◽  
pp. 488-496 ◽  
Author(s):  
J. F. F. Lekkerkerker ◽  
F. van Woudenberg ◽  
H. Doorenbos
Keyword(s):  
Oral Dose ◽  
Turnover Rate ◽  
Low Dose ◽  
Oral Absorption ◽  
Calcium Absorption ◽  
Pool Size ◽  
Absorption Test ◽  
Longterm Treatment ◽  
The One ◽  
Calcium Pool

ABSTRACT The influence of longterm treatment with 15 mg of prednisolone on calcium absorption was investigated by means of an oral absorption test. Plasma-radioactivity was measured one, two and three hours after the oral dose. Sixteen patients were studied before and while on medication during three weeks, eleven of them being re-investigated after five months of treatment. This dose of steroids produced no effect on calcium absorption; two and three hours after the oral dose the plasma-radioactivity is even higher (P < 0.05) while on prednisolone. In six patients the one hour calcium pool size and turnover rate were also measured after iv 45Ca. The pool size and turnover rate were not changed during the treatment.

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