Appendicular and whole body lean mass outcomes are associated with finite element analysis-derived bone strength at the distal radius and tibia in adults aged 40 years and older

Bone ◽  
2017 ◽  
Vol 103 ◽  
pp. 47-54 ◽  
Author(s):  
Jenna C. Gibbs ◽  
Lora M. Giangregorio ◽  
Andy K.O. Wong ◽  
Robert G. Josse ◽  
Angela M. Cheung
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Bone Strength ◽  
Distal Radius ◽  
Lean Mass ◽  
Whole Body ◽  
Element Analysis ◽  
Body Lean Mass

Comparison of the effect of odanacatib and vehicle treatment on HRPQCT based finite element analysis to estimate bone strength at distal radius in rhesus monkeys

Bone ◽  
2010 ◽  
Vol 47 ◽  
pp. S161
Author(s):  
A. Cabal ◽  
E.A. Phillips ◽  
S. Apreleva ◽  
R.Y. Jayakar ◽  
P.J. McCracken ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Bone Strength ◽  
Distal Radius ◽  
Rhesus Monkeys ◽  
Element Analysis ◽  
Vehicle Treatment

Assessment of bone strength through finite element analysis based on radiographs of the forearm

Bone ◽  
2007 ◽  
Vol 40 (6) ◽  
pp. S48-S48
Author(s):  
T HANGARTNER ◽  
B VARGHESE ◽  
M MILLER
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Bone Strength ◽  
Element Analysis

scholarly journals Finite element analysis of bone strength in osteogenesis imperfecta

Bone ◽  
2020 ◽  
Vol 133 ◽  
pp. 115250 ◽  
Author(s):  
Peter Varga ◽  
Bettina M. Willie ◽  
Chris Stephan ◽  
Kenneth M. Kozloff ◽  
Philippe K. Zysset
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Osteogenesis Imperfecta ◽  
Bone Strength ◽  
Element Analysis

scholarly journals Skeletal Microstructure and Estimated Bone Strength Improve Following Parathyroidectomy in Primary Hyperparathyroidism

2017 ◽  
Vol 103 (1) ◽  
pp. 196-205 ◽  
Author(s):  
Natalie E Cusano ◽  
Mishaela R Rubin ◽  
Barbara C Silva ◽  
Yu-Kwang Donovan Tay ◽  
John M Williams ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Bone Density ◽  
Primary Hyperparathyroidism ◽  
Fracture Risk ◽  
Bone Strength ◽  
Failure Load ◽  
Mineral Density ◽  
Element Analysis ◽  
Volumetric Bone Density

Abstract Context High-resolution peripheral quantitative computed tomography (HRpQCT) is a noninvasive imaging technology that can provide insight into skeletal microstructure and strength. In asymptomatic primary hyperparathyroidism (PHPT), HRpQCT imaging has demonstrated both decreased cortical and trabecular indices, consistent with evidence for increased fracture risk. There are limited data regarding changes in HRpQCT parameters postparathyroidectomy. Objective To evaluate changes in skeletal microstructure by HRpQCT in subjects with PHPT after parathyroidectomy. Design We studied 29 subjects with PHPT (21 women, 8 men) with HRpQCT at baseline and 6, 12, 18, and 24 months postparathyroidectomy. Main Outcome Measures Volumetric bone mineral density, microarchitectural indices, and finite element analysis at the distal radius and tibia. Results At both the radius and tibia, there were significant improvements in total, cortical, and trabecular volumetric bone density as early as 6 months postparathyroidectomy (24-month values for total volumetric bone density, radius: +2.8 ± 4%, tibia: +4.4 ± 4%; P < 0.0001 for both), cortical thickness (radius: +1.1 ± 2%, tibia: +2.0 ± 3%; P < 0.01 for both), and trabecular bone volume (radius: +3.8 ± 5%, tibia: +3.2 ± 4%; P < 0.0001 for both). At both sites, by finite element analysis, stiffness and failure load were improved starting at 6 months postparathyroidectomy (24-month values for failure load, radius: +6.2 ± 6%, tibia: +4.8 ± 7%; P < 0.0001 for both). Conclusions These results provide information about skeletal microarchitecture in subjects with PHPT followed through 2 years after parathyroidectomy. Estimated bone strength is improved, consistent with data showing decreased fracture risk postparathyroidectomy.

scholarly journals Finite Element Analysis-Based Vertebral Bone Strength Prediction Using MDCT Data: How Low Can We Go?

2020 ◽  
Vol 11 ◽  
Author(s):  
Nithin Manohar Rayudu ◽  
Karupppasamy Subburaj ◽  
Kai Mei ◽  
Michael Dieckmeyer ◽  
Jan S. Kirschke ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Bone Strength ◽  
Strength Prediction ◽  
Element Analysis ◽  
Vertebral Bone
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