Early gastric cancer and Artificial Intelligence: Is it time for population screening?

Author(s):  
Julia Arribas Anta ◽  
Mario Dinis-Ribeiro
2018 ◽  
Vol 87 (6) ◽  
pp. AB176 ◽  
Author(s):  
Hong Jin Yoon ◽  
Seunghyup Kim ◽  
Jie-Hyun Kim ◽  
Ji-Soo Keum ◽  
Junik Jo ◽  
...  

2019 ◽  
Vol 89 (4) ◽  
pp. 816-817 ◽  
Author(s):  
Yuichi Mori ◽  
Tyler M. Berzin ◽  
Shin-ei Kudo

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 289-289 ◽  
Author(s):  
Tomoyuki Irino ◽  
Hirofumi Kawakubo ◽  
Satoru Matsuda ◽  
Shuhei Mayanagi ◽  
Rieko Nakamura ◽  
...  

289 Background: Early gastric cancer shows lymph node involvement in about 10-15% of patients. Despite the fact, we perform radical lymphadenectomy for all patients because predicting lymph node metastasis has yet to be successful. In this study, we hypothesize that image analysis using artificial intelligence (AI) technology may help solve the problem. Methods: We retrospectively collected 82 patients with clinical T1N0 and pathological node negative and 82 patients with clinical T1N0 and pathological node positives and then divided the 164 patients into a training:validation set in ratio of 9:1. Endoscopic images of the early tumors were analyzed by transfer learning using AlexNet, a deep neural network containing 5 convolutional layers and 3 fully-connected layers. The model was validated with newly-collected 40 images from 20 clinical T1N0 and pathological node negative and 20 patients with clinical T1N0 and pathological node positives as a test set. For comparison, three methods of prediction were implemented: prediction at random, by logistic regression, and by skilled endoscopists. Results: The AI predicted LNM with accuracy of 80.9% in the validation set and 66.9% in the test set. (48.3% for node negative cancers and 85.4% for node positive cancers) On the other hand, prediction at random, by logistic regression, and by 2 endoscopists resulted in 50.3%, 50.0%, and 47.5%, respectively. Conclusions: Although the accuracy still needs to be improved, image analysis using the AI technology resulted in the best prediction of lymph node metastasis, indicating that AI is a promising technology for the diagnosis of lymph node metastasis in early gastric cancer.


2021 ◽  
Vol 8 ◽  
Author(s):  
Jiang Kailin ◽  
Jiang Xiaotao ◽  
Pan Jinglin ◽  
Wen Yi ◽  
Huang Yuanchen ◽  
...  

Background & Aims: Gastric cancer is the common malignancies from cancer worldwide. Endoscopy is currently the most effective method to detect early gastric cancer (EGC). However, endoscopy is not infallible and EGC can be missed during endoscopy. Artificial intelligence (AI)-assisted endoscopic diagnosis is a recent hot spot of research. We aimed to quantify the diagnostic value of AI-assisted endoscopy in diagnosing EGC.Method: The PubMed, MEDLINE, Embase and the Cochrane Library Databases were searched for articles on AI-assisted endoscopy application in EGC diagnosis. The pooled sensitivity, specificity, and area under the curve (AUC) were calculated, and the endoscopists' diagnostic value was evaluated for comparison. The subgroup was set according to endoscopy modality, and number of training images. A funnel plot was delineated to estimate the publication bias.Result: 16 studies were included in this study. We indicated that the application of AI in endoscopic detection of EGC achieved an AUC of 0.96 (95% CI, 0.94–0.97), a sensitivity of 86% (95% CI, 77–92%), and a specificity of 93% (95% CI, 89–96%). In AI-assisted EGC depth diagnosis, the AUC was 0.82(95% CI, 0.78–0.85), and the pooled sensitivity and specificity was 0.72(95% CI, 0.58–0.82) and 0.79(95% CI, 0.56–0.92). The funnel plot showed no publication bias.Conclusion: The AI applications for EGC diagnosis seemed to be more accurate than the endoscopists. AI assisted EGC diagnosis was more accurate than experts. More prospective studies are needed to make AI-aided EGC diagnosis universal in clinical practice.


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