Protective effect of Myrcia pubipetala Miq. against the alteration s in oxidative stress parameters in an animal model of depression induced by corticosterone

2021 ◽  
pp. 147725
Author(s):  
Anna Lydia Shuster ◽  
Fernanda Emilia Rocha ◽  
Sheila Wayszceyka ◽  
Daniela Delwing de Lima ◽  
Sara Cristiane Barauna ◽  
...  
2020 ◽  
Vol 25 (270) ◽  
pp. 128-141
Author(s):  
Victória Branca Moron ◽  
Aline Belem Machado ◽  
Samanta Cristina Siebel de Moraes ◽  
Kalinkaluei Aparecida Rigo ◽  
Micaela da Silva Constante ◽  
...  

Introduction: Particulate matter (PM) is an atmospheric pollutant associated with many deleterious health effects. Oxidative stress is among these effects, that can result from a local inflammatory response to systemic damage to the organism. Studies indicate that when an individual is submitted to aerobic physical training, it generates an antioxidant protective effect that overcomes the damages caused by PM. Objective: Therefore, the aim of this study was to evaluate the influence of the particulate matter PM2.5 and PM10 on the oxidative stress parameters. Methods: The evaluation of the influence of PM on oxidative stress parameters was performed by the dosages of superoxide dismutase, catalase, glutathione peroxidase, and total antioxidant power in male Wistar rats not exposed to the particulate matter, with and without aerobic physical training, and exposed to PM2.5 and PM10, with and without aerobic physical training. This protocol lasted five weeks. Results: The antioxidant enzymes analyzed that presented significant differences were catalase, and glutathione peroxidase. Conclusions: From this research, it was possible to perceive that PM influences negatively on the oxidative stress and in the weight of the rats and that the aerobic exercise generates a protective effect against these damages.


PLoS ONE ◽  
2011 ◽  
Vol 6 (11) ◽  
pp. e27452 ◽  
Author(s):  
Barbara Ambruosi ◽  
Manuel Filioli Uranio ◽  
Anna Maria Sardanelli ◽  
Paola Pocar ◽  
Nicola Antonio Martino ◽  
...  

2019 ◽  
Vol 36 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Özgür Fırat ◽  
Özlem Kaya

In this research, to determine toxicity of mercury (Hg) and whether selenium (Se) has any role in protection of this toxicity, it was investigated the alterations in oxidative stress parameters in tissues of Oreochromis niloticus. For this purpose, fish were exposed to 0.01 and 0.05 ppm Hg and 0.01 ppm Hg+0.01 ppm Se and 0.05 ppm Hg+0.05 ppm Se for 4 and 21 days and activities of superoxide dismutase (SOD) and catalase (CAT) and levels of malondialdehyde (MDA) in gill and liver were determined. It was observed significant changes in all analyzed parameters due to tissue, medium concentration and exposure period in the exposure of mercury alone and Hg+Se mixtures. In Hg alone, and in combination with Se especially in their higher medium concentrations, activities of SOD and CAT in the gill and liver significantly increased at 4 days (P˂0.05), while they significantly decreased at 21 days (P˂0.05). In the exposure of Hg and Hg+Se and in the both tissues, it not determined significant alteration in the MDA levels at 4 days (P˃0.05), while they elevated in their higher concentrations at 21 days (P˂0.05). In conclusion, it was determined the increases or decreases in activities of SOD and CAT and levels of MDA in O. niloticus were higher in the Hg alone than Hg+Se mixtures and selenium has a protective effect on oxidative toxicity of mercury.


2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
K. Buschmann ◽  
Y. Gramlich ◽  
M. Oelze ◽  
A. Daiber ◽  
T. Münzel ◽  
...  

2019 ◽  
Author(s):  
Murat Dağdeviren ◽  
Arzu Or Koca ◽  
Tolga Akkan ◽  
İhsan Ateş ◽  
Salim Neşelioğlu ◽  
...  

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